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Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

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Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery

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If you have a question about this list, please contact: Marko Hyvonen; Professor Sir Tom Blundell; Ben Luisi; xyp20; Mairi Kilkenny. If you have a question about a specific talk, click on that talk to find its organiser.

0 upcoming talks and 160 talks in the archive.

tRNA Modifications and Decoding Errors

UserProfessor Eric Westhof (Institut de Biologie Moléculaire et Cellulaire du CNRS, Université de Strasbourg).

HouseJean Thomas Lecture Theatre, Sanger Biochemistry Building.

ClockWednesday 20 February 2019, 16:00-18:00

A Saposin-lipoprotein nanoparticle system for membrane proteins

UserDr Jens Frauenfeld (CEO Salipro Biotech, Sweden).

HouseJean Thomas Lecture Theatre, Sanger Biochemistry Building.

ClockMonday 03 December 2018, 15:00-17:00

Capturing the 3D Folds of Whole Mammalian Genomes in Single Cells

UserDr Tim Stevens (Cell Biology Division, LMB).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 28 November 2018, 10:15-11:15

Protein:protein recognition in the Ubiquitin Proteasome-degradation System (UPS) and Membrane Surface Complexes from the Ras-family

UserDr Andrew Byrd (Head of Macromolecular NMR, National Cancer Institute, Maryland).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 31 October 2018, 16:00-18:00

Structural studies of a DNA unwinding machine

UserDr Laura Spagnolo (University of Glasgow).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 20 June 2018, 10:15-12:00

Protein and Peptide Mass Spectrometry Analysis

UserDr Anja Andrejeva (Cambridge Centre for Proteomics).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 06 June 2018, 10:30-11:30

Fragment based inhibition of CK2α

UserDr Paul Brear (Hyvonen Group).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 16 May 2018, 10:30-11:30

Substrate reduction enabled by structural biology as therapy for metabolic disorders

UserDr Gustavo Arruda Bezerra (Structural Genomics Consortium – University of Oxford).

HousePerham Seminar Room, Sanger Biochemistry Building.

ClockWednesday 25 April 2018, 10:15-11:15

Not Too Big - Not Too Small: Fragment Antibody Drug Candidates as Alternatives to Antibodies for Solid Tumours

UserDr Gokhan Yahioglu (Director of Medicinal Chemistry, Antikor Biopharma Ltd).

HouseBiochemistry Seminar Room, Sanger Building.

ClockMonday 19 March 2018, 10:15-11:15

Mycobacterium Tuberculosis Physiology: The Intricate Interplay between Drug Tolerance and Drug Resistance

UserCaroline Pule (Faculty of Medicine, Stellenbosch University, South Africa).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 07 March 2018, 10:15-11:15

Human 2-oxoacid-dependent Oxygenases

UserDr M. S. Islam (Department of Biochemistry, University of Cambridge).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 24 January 2018, 10:30-11:15

Signalling through interleukin/interferon receptors: outside and inside of the cell

UserDr. Alexander Wlodawer (Chief, Macromolecular Crystallography Laboratory, NCI-Frederick).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 11 October 2017, 10:15-11:15

Linking Structural Biology and Clinical Genomics: Purine Nucleotidase in Relapsed Leukemia

UserDr. Aleš Hnízda (Academy of Sciences of the Czech Republic, Prague; From 1st June: Department of Biochemistry, University of Cambridge).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 31 May 2017, 10:15-11:15

Rebuilding the HDX-MS Method to Support Integrative Methods in Structural Biology

UserDr David Schriemer (University of Calgary, Alberta).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 10 May 2017, 10:15-11:15

High-Throughput Fragment-Based Drug Discovery at Diamond Synchrotron: Robots can do much of the work to screen in FBDD!

UserProf Frank von Delft (Diamond Light Source / Structural Genomics Consortium - Oxford).

HouseBiochemistry Seminar Room, Sanger Building.

ClockMonday 03 April 2017, 10:15-11:15

COSMIC Catalogue of Cancer Mutations and the 3D Proteome

UserSimon Forbes & Harry Jubb (Sanger Institute, Wellcome Genome Campus).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 29 March 2017, 10:15-11:15

Using Integrative Methods in Structural Biology to Understand Protein Structure

UserDr Daniel Saltzberg (University of California, San Francisco).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 08 March 2017, 10:15-11:15

Computational study of mutations in proteins

UserProfessor Douglas Pires (Centro de Pesquisas René Rachou, FIOCRUZ - Minas Gerais, Brazil).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 01 March 2017, 10:15-11:15

Myc and MexR: conformational selection and fuzzy complexes in transcriptional regulation

UserProf Maria Sunnerhagen (Linkoping University, Sweden).

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockTuesday 28 February 2017, 14:30-15:30

What's new at PDBe?

UserDr Deepti Gupta and Dr John Berrisford (PDBe).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 25 January 2017, 10:15-11:15

A computational framework for optimizing combination drug therapies

UserDr Michael Lyons (Colorado State University).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 26 October 2016, 10:15-11:15

Structure and Function of TIFA - A New Player in Immunity and Cancer

UserProf Ming-Daw Tsai (Academia Sinica in Taiwan).

HouseBiochemistry Seminar Room, Sanger Building.

ClockMonday 10 October 2016, 15:00-16:00

Predicting the impact of natural and disease variants on protein function

UserProfessor Rob Russell (Heidelberg University).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 13 July 2016, 10:15-11:15

Targeting Trehalose and Methylglucose Lipopolysaccharide Pathways of M. tuberculosis

UserNupur Verma (Department of Biochemistry, Cambridge).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 15 June 2016, 10:15-11:15

TBC

UserDr Owen Davies (Newcastle University).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 01 June 2016, 10:15-11:15

Pregnancy outcome prediction using placenta epigenetic data

UserDr Sung Gong (Clinical School of Medicine).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 02 March 2016, 10:15-11:15

Protein transport to the endoplasmic reticulum

UserDr Rebecca Voorhees (LMB).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 20 January 2016, 10:15-11:15

Computational approaches to investigate protein-nucleic acid and protein-protein interactions

UserDr Sony Malhotra (Department of Biochemistry).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 16 December 2015, 10:15-11:15

Mapping of ligand binding site and activation mechanism of APJ receptor

UserPrashant Kumar (Department of Biochemistry).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 02 December 2015, 10:15-11:15

Dr Paul Brear - Inhibiting CK2α from outside the active site

UserPaul Brear - Department of Biochemistry.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 25 November 2015, 10:15-11:15

Prof Song Tan - TBC

UserProfessor Song Tan (Penn State University).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 18 November 2015, 10:15-11:15

Fitting atomic structures into EM density maps

UserDr Arun Prasad Pandurangan (Department of Biochemistry).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 04 November 2015, 10:15-11:15

ARCIMBOLDO, an ab initio approach to MR phasing

UserIsabel Uson (Molecular Biology Institute of Barcelona).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 21 October 2015, 10:15-11:15

Atomic resolution cryoEM structure of bacteriophage

UserProf. Wah Chiu, Baylor College of Medicine, Texas.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 02 September 2015, 10:15-11:15

Modulating Protein-Protein Interactions

UserDr Jessica Holien - St. Vincent's Institute for Medical Research.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 26 August 2015, 15:00-16:00

Title to be confirmed

UserDr Dijana Matak-Vinkovic, Dept. Chemistry, Cambridge.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 24 June 2015, 10:15-11:15

Impact of rapid whole-genome sequencing on diagnostic and public health microbiology

UserDr Claudio U. Köser, Dept. Medicine and Wellcome Trust Genome Campus.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 03 June 2015, 10:15-11:15

Structural Mechanisms in Protein Kinase Regulation

UserProfessor John Kuriyan, Berkeley.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 20 May 2015, 10:15-11:15

Predicting drug-target binding kinetics through enhanced sampling simulations

UserProfessor Francesco Gervasio, Dept. Chemistry, University College London.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 13 May 2015, 10:15-11:15

Biodiversity and Drug Discovery

UserProfessor Glaucius Oliva, Universidade de São Paulo.

HouseBiochemistry Seminar Room, Sanger Building.

ClockThursday 07 May 2015, 16:30-17:30

Dr Meindert Lamers - Title to be confirmed

UserDr Meindert Lamers - LMB.

HouseBiochemistry Seminar Room, Sanger Building, Tennis Court Road.

ClockWednesday 25 February 2015, 10:15-11:15

Dr Isaac Westwood - Title to be Confirmed

UserDr Isaac Westwood - Institute of Cancer Research.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 18 February 2015, 10:15-11:30

Dr Christian Ottmann, Title to be confirmed

UserDr. Christian Ottmann Associate Professor, (UHD) Molecular Cell and Structural Biology, Chemical Biology, Dpt. of Biomedical Engineering and Institute for Complex Molecular Systems, Technische Universiteit, EINDHOVEN.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 04 February 2015, 10:15-11:15

Dr Takashi Ochi and Dr Qian Wu

UserDr Takashi Ochi, Department of Biochemistry, University of Cambridge, u. k.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 21 January 2015, 10:15-11:30

Identification and characterization of interaction sites with MD simulations of mixed solvents – Application to non-standard targets

UserProfessor Xavier Barril, ICREA Research Professor at Barcelona University, Spain.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 12 November 2014, 10:15-11:15

Support Science and Diamond Light Source

UserCarina Lobley, DLS.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 15 October 2014, 10:15-11:15

Professor Randy Read - title to be comfirmed

UserProfessor Randy Read, CIMR, Cambridge.

HouseSeminar Room 2, Hopkins Building.

ClockWednesday 08 October 2014, 10:15-11:15

Structures and mechanisms of macromolecular complexes involved in transcription and DNA repair

UserProfessor Xiaodong Zhang Imperial College London Department of Life Sciences.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 11 June 2014, 10:15-11:15

How insulin binds to the insulin receptor: structural biology and protein engineering

UserDr Michael Weiss, School of Medicine Cleveland, USA.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 09 April 2014, 10:15-11:15

Coot's EM Model-fitting Tools

UserDr Paul Emsley, MRC-LMB, Cambridge, U.K..

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 26 March 2014, 10:15-11:15

Small Angle X-ray Scattering: sample preparation, data collection, and data analysis.

UserDr Meindert Lamers, MRC-LMB, Cambridge, U.K.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 26 February 2014, 10:15-11:15

Cyclofluidic: Quick hit-to-lead optimization using an integrated microfluidic approach

UserDr Ronald Dorenbos, Business Development Director Europe Cyclofluidic Ltd..

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 05 February 2014, 10:15-11:15

Title to be confirmed

UserPaula de Fonseca - LMB.

HouseBiochemistry Seminar Room, Sanger Building.

ClockTuesday 28 January 2014, 10:15-11:30

Using evolutionary sequence variation to make inferences about protein structure and function

UserLucy J. Colwell, Department of Chemistry, University of Cambridge.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 22 January 2014, 10:15-11:15

Protein-Protein Interaction Networks and Diseases

UserFranca Fraternali, Randall Division of Cell and Molecular Biophysics, King's College London, UK .

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 27 November 2013, 10:15-11:15

Analysis of allosteric communication and functional local motions using a Structural Alphabe

UserAlessandro Pandini,Randall Division of Cell and Molecular Biophysics,King's College London, UK .

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 27 November 2013, 10:15-11:15

Chirality as a crossroad of chemistry and biology

UserProfessor Reiko KURODA, Tokyo University of Science (Japan).

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 13 November 2013, 10:15-11:15

Title to be confirmed

UserShaoxia Chen, MRC-LMB, cambridge.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 06 November 2013, 10:15-11:15

Evolution & dynamics of protein complexes

UserSarah Teichmann, Wellcome Trust Sanger Institute.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 30 October 2013, 10:15-11:15

Crystallisation and structure of respiratory complex I, a giant molecular proton pump

UserLeonid Sazanov, MRC Mitochondrial Biology Unit, Wellcome Trust / MRC Building, cambridge.

HouseBiochemistry Seminar Room, Sanger Building.

ClockWednesday 23 October 2013, 10:15-11:15

Open Source Drug Discovery:  Developing a Systems Level Translational Platform for Neglected Diseases

UserProf. Samir K. Brahmachari, Founder Director, Institute of Genomics and Integrative Biology,  Director General, Council of Scientific & Industrial Research,  Delhi, India.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockFriday 22 March 2013, 13:00-14:00

PHASER workshop

UserAirlie McCoy, CIMR, University of Cambridge.

HousePerham's seminar room.

ClockWednesday 27 February 2013, 10:15-11:15

OPPF-UK: a national resource centre for protein production.

UserDr Louise Bird, OPPF, UK.

HousePerham's seminar room.

ClockWednesday 13 February 2013, 10:15-11:15

Identifying hot-spots and designing small molecule inhibitors at protein-protein interfaces: taking advantage of bound water networks

UserDr David J. Huggins, Department of Oncology Hutchison/MRC Research Centre.

HousePerham's seminar room.

ClockWednesday 07 November 2012, 10:15-11:15

Title to be confirmed

UserHelen Saibil.

HousePerham's seminar room.

ClockWednesday 13 June 2012, 10:15-11:15

Structural studies of chromosome segregation

UserMartin Singleton.

HousePerham's seminar room.

ClockWednesday 02 May 2012, 10:15-11:15

SAXS studies on biological molecules at Diamond Light Source

UserInoue Katsuaki, DLS, UK.

HousePerham's seminar room.

ClockWednesday 25 April 2012, 10:15-11:15

Domain swapping in proteins

UserDr Sowdhamini, National Centre for Biological Sciences (TIFR) UAS-GKVK Campus Bellary Road Bangalore 560 065 INDIA.

HousePerham's seminar room.

ClockWednesday 21 December 2011, 10:15-11:15

To be confirmed

UserDr Bissan Al-Lazikani, Computational Biology and Chemogenomics Institute of Cancer Research, U.K.

HousePerham's seminar room.

ClockWednesday 07 December 2011, 10:15-11:15

Low Resolution Crystallography

UserDr Dima Chirgadze, Biochemistry Department, University of Cambridge.

HousePerham's seminar room.

ClockWednesday 30 November 2011, 10:15-11:15

Making candy for signal transduction research - Adventures in Willy Wonka land

UserProf Morten Grötli, Department of Chemistry, University of Gothenburg.

HousePerham's seminar room.

ClockThursday 24 November 2011, 11:00-12:00

Low resolution refinement tools in the program REFMAC

UserDr Garib N Murshudov, LMB, MRC, Cambridge, U.K.

HousePerham's seminar room.

ClockWednesday 23 November 2011, 10:15-11:15

Fuzzy complexes: ambiguity in protein-protein and protein-DNA interactions

UserProfessor Monika Fuxreiter Institute of Enzymology, Budapest, HUNGARY and LMB, MRC, Cambridge, UK.

HousePerham's seminar room.

ClockWednesday 16 November 2011, 10:15-11:15

Structural complexomics of eukaryotic gene expression.

UserDr Imre Berger, EMBL, Grenoble, France.

HouseSeminar Room, Sanger Building.

ClockWednesday 27 July 2011, 10:15-11:00

Receptor-based Drug Discovery

User Dr Jiye Shi, UCB Celltech.

HouseSeminar Room, Sanger Building.

ClockWednesday 13 July 2011, 10:15-11:00

Crystal dehydration: Experimental design with a home source and at the synchroton

User Dr Juan Sanchez Weatherby: Diamond, UK.

HouseSeminar Room, Sanger Building.

ClockWednesday 22 June 2011, 10:15-11:00

Designing Bioactive Molecules and Mode-of-Action Analyses - The Benefits of Learning From the Past.

UserDr Andreas Bender, Unilever Centre, Cambridge.

HouseSeminar Room, Sanger Building.

ClockWednesday 15 June 2011, 10:15-11:00

Drug Protein Interaction Databases

UserAdrian Schreyer, Alicia Higueruelo, Will Pitt.

HouseSeminar Room, Sanger Building.

ClockWednesday 26 January 2011, 10:15-11:00

The Ghosts of PDBe Past, Present  and Yet to Come

UserDr Gerard Kleywegt, PDB Europe, EBI, Hinxton.

HouseSeminar Room, Sanger Building.

ClockWednesday 12 January 2011, 10:15-11:00

i-SITE: An energetic approach to predict ligand-binding site on protein surface

UserDr Mizuki Morita, Laboratory of Bioinformatics, National Institute of Biomedical Innovation (NIBIO), Japan.

HouseSeminar Room, Sanger Building.

ClockMonday 10 January 2011, 11:30-12:00

The rational design of small-molecule Neuropilin-1 antagonists

UserTrevor Perrior, Research Director of Domainex.

HouseSeminar Room, Sanger Building.

ClockWednesday 14 July 2010, 10:15-11:00

Restraints on Protein Models from NMR Chemical Shifts

UserRinaldo Wander Montalvao (Chemistry, Cambridge)..

HouseSeminar Room, Sanger Building.

ClockWednesday 07 July 2010, 10:35-11:00

Software for fragment linking and growing.

UserNikolay Todorov (Molscape).

HouseSeminar Room, Sanger Building.

ClockWednesday 07 July 2010, 10:15-11:00

Using Biacore for fragment screening

UserCatherine McDonnell, GE Healthcare.

HouseSeminar Room, Sanger Building.

ClockWednesday 30 June 2010, 10:15-11:00

Targetting Protein-Protein Interactions: Synergies between NCEs and New Antibodies.

UserDr Alastair Lawson (UCB- Celltech).

HouseSeminar Room, Sanger Building.

ClockWednesday 16 June 2010, 10:15-11:00

Fragment-based drug discovery using X-ray crystallography.

UserDr Anne Cleasby (Astex).

HouseSeminar Room, Sanger Building.

ClockWednesday 02 June 2010, 10:15-11:00

Can machines understand the Scientific Literature?

UserProfessor Peter Murray Rust (Unilever Centre, Chemistry, Cambridge).

HouseSeminar Room, Sanger Building.

ClockWednesday 19 May 2010, 10:15-11:00

Engineering proteins for fragment screening

UserSpeaker to be confirmed.

HouseSeminar Room, Sanger Building.

ClockWednesday 17 March 2010, 10:15-11:00

Surface Plasmon Resonance

UserSpeaker to be confirmed.

HouseSeminar Room, Sanger Building.

ClockWednesday 10 March 2010, 10:15-11:00

STING_DB

User Dr Goran Neshi, Laboratorio de Biologia Computacional, Cidade Universitária "Zeferino Vaz" , Campinas, Brazil.

HouseSeminar Room, Sanger Building.

ClockWednesday 24 February 2010, 10:15-11:00

Drug-protein Databases: ZINC, Credo, CHEMBL

UserWill; Adrian.

HouseSeminar Room, Sanger Building.

ClockWednesday 17 February 2010, 10:15-11:00

Fragments versus traditional screening . Off-target analysis

UserSpeaker to be confirmed.

HouseSeminar Room, Sanger Building.

ClockWednesday 10 February 2010, 10:15-11:00

ITC

UserLeo and Marko.

HouseSeminar Room, Sanger Building.

ClockWednesday 03 February 2010, 10:15-11:00

X-ray single soaks or cocktails? Growing versus Linking. 

UserRound table (Tom and May to lead), Dave Huggins.

HouseSeminar Room, Sanger Building.

ClockWednesday 27 January 2010, 10:15-11:00

Targetting PPI

UserAlicia and Narcis Fernandez-Fuentes from the Leeds Institute of Molecular Medine (LIMM).

HouseSeminar Room, Sanger Building.

ClockWednesday 20 January 2010, 10:15-11:00

Recap of Experimental Fragment-based projects

UserMay, Marko, Anja, Anna, Michal, Sachin, Marcio, Leo, Noha.

HouseSeminar Room, Sanger Building.

ClockWednesday 13 January 2010, 10:15-11:00

Completely in vitro protein engineering automation

UserProf Homme Hellinga, Duke University.

HouseLecture theatre, Sanger Building.

ClockMonday 16 November 2009, 16:00-17:00

Molecular recognition - from single target to protein complexes

UserDr Agata Kranjc Pietrucci from International School of Advanced Studies, Trieste, Italy.

HouseSeminar Room, Sanger Building.

ClockThursday 15 October 2009, 11:00-12:00

HIV-1 Reverse Transcriptase: Structure, Drug Resistance, and Drug Design

UserProfessor Eddy Arnold, Rutgers University.

HouseLecture theatre, Sanger Building.

ClockThursday 11 June 2009, 16:00-17:00

Public domain medicinal chemistry data at the EBI and the use in drug discovery

UserDr John Overington, Chemogenomics and ChEMBL Databases, European Bioinformatics Institute (EMBL-EBI).

HouseSeminar Room, Sanger Building.

ClockWednesday 11 March 2009, 10:00-11:00

Protein Crystal Growth in Gels and Capillary Tubes

UserProfessor Abel Moreno.

HouseSeminar Room, Sanger Building.

ClockWednesday 04 February 2009, 10:15-11:00

Conventional and non-conventional methods of protein crystal growth

UserProfessor Abel Moreno.

HouseSeminar Room, Sanger Building.

ClockWednesday 28 January 2009, 10:15-11:00

Recent adventures in protein folding and design

UserProfessor Lynne Regan, Yale University.

HouseUnilever Lecture Theatre, Department of Chemistry.

ClockMonday 15 December 2008, 11:00-12:00

Leaving drinks for Sheena

UserDr Sheena D'Arcy.

HousePanton Arms pub, Panton Street.

ClockFriday 05 December 2008, 17:30-23:59

SPR - theory and practise

UserDr Joe Maman.

HouseMeeting Room A.

ClockThursday 04 December 2008, 13:00-14:00

Biocore

UserSpeaker to be confirmed.

HouseLecture Theatre, Department of Biochemistry, Hopkins Building (old building).

ClockWednesday 03 December 2008, 16:00-17:00

Expression systems for protein complexes

User Dr Imre Berger, EMBL, Heidelberg.

HouseLecture Theatre, Department of Biochemistry, Hopkins Building (old building).

ClockWednesday 19 November 2008, 16:00-17:00

Pathway-based analysis of genome-wide siRNA screens

UserDr. Miguel Camargo, Merck, Boston USA.

HouseSeminar Room, Sanger Building.

ClockWednesday 12 November 2008, 10:15-11:00

Party for Richard and Timo

UserAll welcome!.

HouseSeminar Room, Sanger Building.

ClockFriday 24 October 2008, 15:00-16:00

Fragment-based Screening and It's Role in Ontario Cancer Institute

UserProf Nickolay Chirgadze, Department of Pharmacology and Toxicology, University of Toronto.

HouseSeminar Room, Sanger Building ?.

ClockSunday 12 October 2008, 11:15-12:00

Molecular Puzzles: Learning About Function and Mechanism of Enzymes From their Structures

UserDr. Alex Wlodawer, Macromolecular Crystallography Laboratory, National Cancer Institute Frederick.

HouseSeminar Room, Sanger Building.

ClockFriday 10 October 2008, 13:00-14:00

test

UserSpeaker to be confirmed.

HouseSeminar Room, Sanger Building.

ClockThursday 14 August 2008, 10:30-11:30

Neurotrophic factors in Drosophila

UserDr Alicia Hidalgo, University of Birmingham.

HouseSeminar Room, Sanger Building.

ClockFriday 18 July 2008, 10:30-11:30

Small hydrogen-bonded motifs in proteins and their significance for amyloid formation

UserJames Milner-White, University of Glasgow.

HouseSeminar Room, Sanger Building.

ClockThursday 26 June 2008, 11:30-12:30

DNA site-specific recombination: Architecture of a recombinase

UserProfessor Marshall Stark University of Glasgow.

HouseSeminar Room, Sanger Building.

ClockWednesday 09 April 2008, 12:00-13:00

Mechanisms of Transmembrane Transport: towards structures of membrane protein drug targets

UserProfessor Robert Stroud, University of California, San Francisco.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockMonday 07 April 2008, 13:00-14:00

Toll like receptors - Investigating innate immunity and infection

UserDr Kathy Triantafilou, Infection and immunity Group, University of Sussex.

HouseSeminar Room, Sanger Building.

ClockFriday 28 March 2008, 10:30-11:30

High intrinsic binding specificity mediates the interactions of a yeast SH3 domain

UserDr. Elliott Stollar, Program in Molecular Structure and Function, Hospital for Sick Children, Toronto.

HouseSeminar Room, Sanger Building.

ClockFriday 14 March 2008, 12:00-13:00

Expriences in Structure-based Discovery

UserProf Rod Hubbard, Vernalis and University of York.

HouseSeminar Room, Sanger Building.

ClockMonday 03 March 2008, 09:00-10:00

Fragment based drug discovery - from crystal to clinic

UserDr David Rees, Astex Therapeutics.

HouseSeminar Room, Sanger Building.

ClockMonday 03 December 2007, 09:00-10:00

Paradoxical Features of Nicotinic Receptor

UserProfessor Stuart Edelstein, University of Geneva.

HouseSeminar Room, Sanger Building.

ClockWednesday 14 November 2007, 12:00-13:00

New protein purification columns and media from GE Healthcare

UserPenny Hamlyn, GE Healthcare.

HouseSeminar Room, Sanger Building.

ClockThursday 08 November 2007, 11:00-12:00

Structural basis of fatty acid synthesis catalyzed by giant multienzyme complexes

UserDr Nenad Ban, Professor of Structural Molecular Biology, ETH Zurich, Swiss Federal Institute of Technology.

HouseSeminar Room, Sanger Building.

ClockFriday 02 November 2007, 14:15-15:15

The long and the short: virulence proteins from Staphylococcus and Streptococcus

UserProfessor Ted Baker, Director, Centre for Molecular Biodiscovery.

HouseBiochemistry Lecture Theatre, Sanger Building.

ClockFriday 19 October 2007, 15:00-16:00

Please see above for contact details for this list.

 

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