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Neurofibromatosis: identification of therapies for peripheral nervous system tumors targeting RAS-GTP and Purinergic signalling

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CRUK Cambridge Institute Scientists Society Biannual Seminar Series proudly presents Dr. Nancy Ratner

Dr. Ratner is interested in the brain in Neurofibromatosis type 1 and Rasopathies, and in peripheral nerve tumors that occur in the Neurofibromatoses, NF1 and NF2 . She uses genomics, animal, and cell culture models to study neurofibroma formation and neurofibroma therapeutics. Ratner received her bachelor’s degree from Brown University, her doctorate from Indiana University, Bloomington (during which time she was a student in the Neurobiology Course at MBL ), and was a postdoctoral fellow at Washington University in St. Louis. A member of the faculty at the University of Cincinnati from 1987 – 2004, she is currently a Professor in the Department of Pediatrics, Cincinnati Children’s Hospital, University of Cincinnati, and the Program Leader for Cancer Biology and Neural Tumors Program in the Cancer and Blood Disorders Institute where she also co-Leads the Rasopathy Program and holds the Beatrice C. Lampkin Endowed Chair in Cancer Biology. She has served on numerous national and international review panels and authored over 100 peer-reviewed manuscripts and 30 reviews. She was awarded the von Recklinghausen Award in 2010, and received a Jacob K. Javits NIH Neuroscience Investigator Award in 2014.

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