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LMB Seminar Series - Pathogen restriction and host specificity: insights from the human pathogen Salmonella Typhi

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Salmonella Typhi continues to be a serious global health concern, resulting in more than 200,000 annual deaths. A distinguishing feature of S. Typhi is that it only infects humans, causing a life-threatening systemic infection known as “typhoid fever”. This is in sharp contrast to most other Salmonellae, which can infect a variety of hosts and are usually associated with self-limiting gastroenteritis (i. e. “food poisoning”). The molecular bases for Salmonella Typhi’s unique pathogenesis and host specificity will be discussed.

This talk is part of the MRC LMB Seminar list series.

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