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Systems Biology: from models (and model organisms) to medicines

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If you have a question about this talk, please contact Duncan Simpson.

Systems Biology aims at an integrative view of biological processes. To achieve such a view, comprehensive data sets are required concerning the levels of macromolecules and metabolites within cells and tissues, together with information about the dynamic interactions between the different classes of molecules. Integration is achieved by building computer models of the systems studied such that predictions of systems behaviour may be made and tested by further experiments in the laboratory. At present, all of this is most readily achieved using model organisms and the Cambridge Systems Biology Centre (CSBC) concentrates on two such organisms – the fruit fly and yeast. These model organisms have real, and immediate, relevance to how we can discover new medicines and drug targets, deliver drugs to their targets, minimise side-effects, and optimise the production of pharmaceuticals. The talk will illustrate the exploitation of systems biology approaches with examples from the work of CSBC

This talk is part of the Horizon: Bioengineering series.

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