One becomes two: assemblies that split cells across evolution

Add to your list(s) Download to your calendar using vCal

• Dr Anđela Šarić, IST Austria
• Wednesday 09 March 2022, 14:30-15:30
• Zoom and Dept of Chemistry, Wolfson Lecture Theatre.

If you have a question about this talk, please contact Lisa Masters.

https://zoom.us/j/92220720173?pwd=WWVpVzVRY3dGRlhCRnFJZE81enRlUT09 Meeting ID: 922 2072 0173 Passcode: 070083

The molecular machinery of life is largely created via self-organisation of individual molecules into functional larger-scaled assemblies. Such processes are multi-scale in nature and constantly driven far from thermodynamic equilibrium. Our group develops minimal coarse-grained models to investigate how driven macromolecular assemblies result in living machines, and how such processes can fail, leading to diseases.

Today I will present our research on computational modelling of active elastic protein filaments that dynamically change their conformations to reshape and cut cells. I will present the comparison of our simulation results to live cell data on reshaping processes across evolution — from cellular trafficking to cell division. I will finish with our recent efforts in computationally evolving assemblies that perform a desired function. Beyond their biological context, our models can help guide the design of artificial structures that are able to mimic life at the nanoscale.

This talk is part of the Theory - Chemistry Research Interest Group series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Department of Chemistry
• Featured lists
• Lennard-Jones Centre external
• School of Physical Sciences
• Zoom and Dept of Chemistry, Wolfson Lecture Theatre

Note that ex-directory lists are not shown.