Probing the dynamics of chronic disease using stable isotopes and mass spectrometry

Add to your list(s) Download to your calendar using vCal

• Dr Robert Busch, ARC Senior Research Fellow, Department of Medicine, University of Cambridge
• Wednesday 28 April 2010, 11:30-12:30
• Seminar Room, Centre for Physics of Medicine (PoM).

If you have a question about this talk, please contact Duncan Simpson.

Chronic disease is characterised by insidious or intermittent homeostatic dysregulation, leading to persistent disruption of normal organ function. Its course is often difficult to predict, in part because underlying causal networks or disease-critical pathways are difficult to probe on relevant time scales. One approach to this problem is to measure homeostatic dysregulation of critical pathways directly to uncover incipient change. This talk will highlight the use of macromolecular biosynthetic labelling with heavy water to probe normal and pathologically altered homeostasis. Methodological developments and challenges will be discussed, as well as applications in the study of autoimmune diseases.

This talk is part of the Physics of Medicine (PoM) Seminar Series series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Biology
• CamBridgeSens
• Cambridge talks
• Life Science Interface Seminars
• Life Sciences
• Life Sciences
• ME Seminar
• Physics of Living Matter - PLM
• Physics of Medicine (PoM) Seminar Series
• School of Physical Sciences
• Seminar Room, Centre for Physics of Medicine (PoM)
• Trust & Technology Initiative - interesting events
• my_list
• other talks

Note that ex-directory lists are not shown.