University of Cambridge > Talks.cam > Plant Sciences Research Seminars > Rapid evolution of the RNA polymerase 3 transcriptome in mammals

  Browse A-Z

Log in

Cambridge users (raven)details Other usersdetails No account?details

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

Rapid evolution of the RNA polymerase 3 transcriptome in mammals

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact ag586.

Transfer ribonucleic acids (tRNAs) are the crucial molecular adaptors that convert genetic information into proteins in every living organism. We combined computational and experimental approaches to characterize the identity, conservation, and divergence of the active tRNA loci transcribed by RNA polymerase 3 in livers of five mammalian species. A core set of tRNA loci was active in all mammals that together encompassed all known 46 tRNA isoacceptor classes. We further confirmed the transcription of tRNAs by sequencing the actual tRNAs. Unexpectedly, we further discovered that specific tRNAs give rise to a large number of small RNA that show hallmarks of a highly specific, nucleolytic processing mechanism. Since these tRNA derived small RNAs originate from distinct loci in each species the regulatory roles of these small RNAs play must be highly species-specific.

This talk is part of the Plant Sciences Research Seminars series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Cambridge Climate Anglia Ruskin University - Community Engagement Graduate and internship applications

Other talks

The role of myosin VI in connexin 43 gap junction accretion CANCELLED - Methodology Masterclass: Exploring the pedagogic possibilities of new diaspora formations and transnationalism. Developing an optimisation algorithm to supervise active learning in drug discovery Renationalisation of the Railways. A CU Railway Club Public Debate. Sacred Mountains as Flood Refuge Sites in Northwest North America An exploration of grain growth & deformation in zirconium TBC 100 Problems around Scalar Curvature Speculations about homological mirror symmetry for affine hypersurfaces Computing High Resolution Health(care) BP KEYNOTE LECTURE: Importance of C-O Bond Activation for CO2/COUtilization - An Approach to Energy Conversion and Storage
 

© 2006-2024 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity