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The Evolution of Long ncRNAs and Prdm9, a Speciation Gene

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Dobzhansky famously argued that “Nothing in biology makes sense except in the light of evolution”. In this talk I’ll describe the results of two projects that have taken his advice. First, I’ll show how we have used evolutionary approaches to investigate whether long noncoding RNA loci are likely to be functional. Then, I’ll describe what might be the fastest evolving human gene which now appears to be critical for specifying sites of recombination.

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