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University of Cambridge > Talks.cam > Isaac Newton Institute Seminar Series > Simulation of ancestral histories of genes
Simulation of ancestral histories of genesAdd to your list(s) Download to your calendar using vCal
If you have a question about this talk, please contact Mustapha Amrani. This talk has been canceled/deleted An empirical distribution of the stochastic history of a sample of genes, conditional on their types, can be found by an advanced simulation technique of sequential importance sampling (SIS) on coalescent histories. If the sample data are DNA sequences, then the pattern of mutations provides information about the ancestral tree of the data. For example, empirical distributions of the time to the most recent common ancestor of the genes and ages of mutations, conditional on the tree topology, can be found. Coalescent processes looking back in time are dual processes to diffusion process models of how gene frequencies evolve forward in time. Proposal distributions for SIS in coalescent histories can be constructed from the generator of the diffusion process. This talk will sketch the SIS technique and present examples of ancestral inference. This talk is part of the Isaac Newton Institute Seminar Series series. This talk is included in these lists:This talk is not included in any other list Note that ex-directory lists are not shown. |
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