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Can yeast and a Robot Scientist help us design therapies for diseases like cancers and malaria?

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We are dependent on the budding yeast Saccharomyces cerevisiae for our daily bread, beer, and wine. Yeast is also a major organism in modern biotechnology, as well as an important experimental model with which to understand the biology of human cells. In this talk, I will explain that yeast provides important lessons concerning how loss of gene copies may lead to cells becoming cancerous. I will also show how we can engineer yeast to mimic human parasites that are difficult or impossible to grow in culture. The use of these yeast mimics, in conjunction with a Robot Scientist, to screen for novel antiparasite compounds will be demonstrated.

This talk is part of the Wolfson College Science Society talks series.

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