University of Cambridge > > Cancer Metabolism Interest Group Seminars > Oncogenes and Tumour Metabolism

Oncogenes and Tumour Metabolism

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If you have a question about this talk, please contact Dr Ireena Dutta.

Glucose and glutamine are two major nutrients that provide cells with ATP and intermediates for various biosynthetic processes. Glucose and glutamine metabolism can interact in various metabolic pathways required for cell proliferation and survival. This interaction varies among proliferation and differentiation states and can be affected by multiple factors, including oncogenes. We are using mouse models of tissue-specific tumourigenesis to evaluate the relationship between distinct tumour-initiating lesions and changes in main pathways of glucose and glutamine metabolism in vivo. This approach should help to design more effective therapeutic strategies tailored to specific types of tumours.

This talk is part of the Cancer Metabolism Interest Group Seminars series.

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