Rho GTPases in pulmonary vascular remodelling

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• Dr Beata Wojciak-Stothard, Imperial College London
• Thursday 18 April 2013, 13:00-14:00
• Seminar room 3, Clinical School, Addenbrookes.

If you have a question about this talk, please contact Eve Dillon.

Rho GTPases, best known for their regulatory role in actin dynamics, stimulate a variety of processes important in control of vascular function, including morphogenesis, migration, cell proliferation and adhesion, cell survival, gene expression, vesicle transport and microparticle formation. Recent data implicate Rho GTPase RhoB in the regulation of pulmonary vascular remodelling in pulmonary hypertension. This lecture will discuss signalling mechanisms involved in Rho-induced pulmonary vascular dysfunction and identify potential targets for pharmacological intervention.

This talk is part of the Vascular Biology Research Seminars series.

This talk is included in these lists:

• Seminar room 3, Clinical School, Addenbrookes
• Vascular Biology Research Seminars

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