University of Cambridge > Talks.cam > Trinity College Science Society (TCSS) > Tracking proteins inside cells

Tracking proteins inside cells

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact .

In biology, localisation is function. Cells display a complex sub-cellular structure with numerous distinct niches responsible for specific biological processes. Consequently, not only must proteins be present to accomplish their biological functions, but they must be localised at their intended sub-cellular locations. In contrast, mislocalised proteins can have serious advert consequences. We will review and understand how contemporary experimental and computational technologies can be used to create sub-cellular localisation maps for thousands of proteins.

Suggested reading

General background: 1. Wikipedia cell article, in particular the subcellular components section 2. Wikpedia protein article, in particular the cellular localization section

Relevant reviews: 3. Yan et al. 2009 4. Gatto et al. 2010

Software: 5. pRoloc – A unifying bioinformatics framework for organelle proteomics

[1] http://en.wikipedia.org/wiki/Cell_(biology) [2] http://en.wikipedia.org/wiki/Protein [3] http://www.ncbi.nlm.nih.gov/pubmed/19110081 [4] http://www.ncbi.nlm.nih.gov/pubmed/21080489 [5] http://www.bioconductor.org/packages/devel/bioc/html/pRoloc.html

This talk is part of the Trinity College Science Society (TCSS) series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.

 

© 2006-2021 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity