University of Cambridge > Talks.cam > Isaac Newton Institute Seminar Series > Species identification from medical metagenomic sequence data

Species identification from medical metagenomic sequence data

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact Mustapha Amrani.

Mathematical, Statistical and Computational Aspects of the New Science of Metagenomics

Species identification from metagenomic sequence data has attracted considerable attention recently, and a number of software solutions are now available, based on whoe-genome assemblies, mapping to references, or informative kmers. In this talk I focus on a small corner of this area, that of species identification from medical samples, where we have an idea from the patient’s condition (and perhaps from inspection of culture) what genus of bacterium we expect to find, but we do not know if there is a mixture. I specifically look at the case of Staphylococcus aureus, a commensal organism which lives in the noses of ~30% of us, and yet which can be a pathogen. Many assemblies of S. aureus strains are present, but generally only one assembly per species for other Staphylococcus species (some of which can cause illness). I’ll talk about how we can address the issues which arise when we want confident answers in the face of such a biased set of prior information.

This talk is part of the Isaac Newton Institute Seminar Series series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.

 

© 2006-2024 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity