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A Pint of Knowledge: The Chemistry of Peptides: "small proteins" fighting "big diseases"

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If you have a question about this talk, please contact Dr. Maria Jimenez-Sanchez.

A Pint of Knowledge is a series of informal research seminars in the pub where members of the society of Spanish Researchers in the UK (SRUK) explain their research to a general audience. It takes place every 2 months and is open to the general public.

Peptides are short chains of amino acids that can be found in places as far apart as the depths of the Caribbean Sea, the African and Asian deserts and our body. Peptides have great potential as medicines, having the same components as proteins they can selectively interact with the protein causing a disease or modulate protein-protein interactions. Historically, the major limitations of peptides have been poor stability in our body and lack of cell permeability which prevented them from reaching their target proteins and have a therapeutic effect. Recently, chemists have found ways of obtaining peptides that are stable and cell permeable and the approvals of new peptidic medicines are increasing year after year. I will introduce you to the peptide world, discussing how we can make them in the lab using from tea-bags to “Breaking Bad-type” chemistry, what properties make them interesting to the pharmaceutical industry and how they can cure big diseases.

This talk is part of the Spanish Researchers in UK (SRUK)-Cambridge series.

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