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The Mechanical Basis of Morphogenesis

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If you have a question about this talk, please contact Salvatore Tesoro.

The development of an adult organism from a single cell requires complex shapes to emerge from simple ones. Such spontaneous shape formation is normally understood within Turing’s reaction diffusion framework: chemical morphogens first set up spatial patterns then couple to growth to produce shapes. In this talk I will discuss a growing body of evidence that the shapes of biological organs are often sculpted directly by mechanical forces, without preliminary chemical patterning. In particular, I will discuss recent work on how the gut loops and how villi form, and some of my own results on the folding of the eye’s ciliary muscle and the folding of the outer surface of the brain.

This talk is part of the Biological and Statistical Physics discussion group (BSDG) series.

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