University of Cambridge > Talks.cam > Foster Talks > "Diabetes, Obesity & Metabolic Disease: Is It All In Our Head?": Elucidating Mechanisms of Central Metabolic Control

"Diabetes, Obesity & Metabolic Disease: Is It All In Our Head?": Elucidating Mechanisms of Central Metabolic Control

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“Work in our laboratory is concerned with the role of the brain and particularly the autonomic nervous system, in diabetes mellitus and obesity. Early experiments on rabbits by Claude Bernard almost 150 years ago have linked lesions in the dorsal vagal complex of the brainstem with diabetes. Similarly, many diabetic patients present with autonomic imbalance, and particularly a loss of vagal activity. We are using rodent models combined with pharmacogenetics, and a combination of molecular, optical, immunocytochemical and electrophysiological techniques to elucidate the role of the autonomic nervous system in metabolic control in vitro and in vivo.”

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http://iris.ucl.ac.uk/iris/browse/profile?upi=STRAP42

http://www.imperial.ac.uk/AP/faces/pages/read/Home.jsp?person=s.trapp&_adf.ctrl-state=1asswpfzgt_3

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