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Molecular dissection of CLE signaling pathways in Arabidopsis

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Secreted peptide hormones, CLV3 /ESR (CLEs) consist of 12 or 13 amino acids with or without arabinosyl modification. Biochemical analyses and genetic analyses suggested at least three independent receptor complexes, CLV1 , CLV2-CRN/SOL2, and RPK2 receive CLV3 peptides to restrict SAM size. We performed comprehensive genetic screening to isolate CLE peptide insensitive mutants by using EMS treated seeds of Col, clv2, and rpk2. We have isolated around 100 mutants which showed peptide resistance, and have identified many causal genes of these mutants. Here, I will introduce about our recent work of AGB1 , PUB4, and some others as CLE signaling molecules.

This talk is part of the Sainsbury Laboratory Seminars series.

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