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Migration of neuronal and immune cells in forebrain wiring

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Forebrain functioning relies on complex circuits that begin to be established in the embryo via an integrated choreography of neuronal migration and axonal navigation. Such developmental programs can be perturbed by activation of the immune system, as illustrated by the fact that prenatal inflammation is a major risk factor for schizophrenia and autism spectrum disorders. Here, we will explore how neuronal migration and tract formation are coordinated in vivo and how cells of the immune system, microglia, contribute to normal and pathological forebrain wiring.

This talk is part of the Foster Talks series.

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