Estimating the global burden of disease attributable to excess sodium within the GBD2010 study

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• Dr John Powles, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge.
• Thursday 04 February 2016, 11:00-12:00
• Meeting rooms, Level 4 Institute of Metabolic Sciences, Addenbrooke’s Treatment Centre (ATC).

If you have a question about this talk, please contact Paul Browne.

Sodium intake increases blood pressure, a risk factor for cardiovascular disease. In Global Burden of Disease (GBD) study we carried out a study to model the estimated effect of sodium consumption on mortality. We quantified global sodium intake, by age, sex, and country, based on urinary and dietary surveys from 66 countries representing 74.1% of the world population. We quantified blood pressure effects of sodium, by age, race, and hypertension, in a new meta-analysis of 107 trials; and blood pressure effects on cardiovascular mortality, by age, from meta-analysis of cohorts. Cause-specific mortality was derived from the 2010 Global Burden of Diseases Study. We estimated cardiovascular impacts of current sodium intake, compared with reference intake of 2.0 g/d, using comparative risk assessment, by age, sex, and country. In this modelling study, 1.65 million cardiovascular deaths were attributed to sodium consumption above a reference level of 2.0 g/d.

This talk is part of the MRC Epidemiology and CEDAR Seminars series.

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