University of Cambridge > Talks.cam > BTRU Seminar Series > Insights into iron metabolism and iron deficiency from studies of blood donors

Insights into iron metabolism and iron deficiency from studies of blood donors

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Blood donation can be viewed as a large clinical study to examine the effects of repeated phlebotomy of approximately 10% of blood volume in otherwise healthy individuals. In the United States about 40,000 people per day donate blood. Donors are from all racial/ethnic backgrounds, range in age from 16 to over 80 years old. In addition, they are altruistic by nature and willing to participate in research studies. This rich population has been used for studies on iron metabolism and red blood cell biology that will be presented. These include a large study of the demographics of anemia, the identification and characterization of “superdonors” and associated genetic variants, a study detailing the recovery of hemoglobin and iron stores following donation and a clinical trial investigating different methods to mitigate iron deficiency in frequent blood donors.

This talk is part of the BTRU Seminar Series series.

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