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Anomalous diffusion in biological membranes and their mathematical description

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SDB - Stochastic Dynamical Systems in Biology: Numerical Methods and Applications

I will present results from Molecular Dynamics simulations of pure andcrowded lipid bilayer systems, giving evidence of anomalous diffusion.While in the pure lipid bilayer this anomaly is very short ranged, theaddition of colesterols or the passage to the gel phase leads to exten-ded anomalous diffusion.  The character of the dynamics corresponds tothat of the fractional Brownian motion in the dilute bilayer, changingto non-Gaussian motion when the bilayer is crowded with proteins. Realbiological membranes show macroscopic anomalous diffusion, which is ev-idenced from superresolution microscopy experiments. In particular themotion becomes non-ergodic and ageing.

This talk is part of the Isaac Newton Institute Seminar Series series.

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