University of Cambridge > Talks.cam > Computational and Systems Biology > Monkeys on Trees: A Bayesian Approach to Inferring Primate Divergence Times

Monkeys on Trees: A Bayesian Approach to Inferring Primate Divergence Times

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In order to estimate the age of the primates, it is necessary to use the fossil record. The fossil record, however, is incomplete and so the age of the oldest primate fossil can only give a lower bound on the age of the primates. In this talk I give a modelling approach to estimating species divergence times, concentrating on the primates.

Due to the nature of the branching process model that we use, we are unable to compute the likelihood function and are thus unable to use standard inference techniques such as Markov chain Monte Carlo (MCMC). Instead, I will present a simple likelihood free method known as Approximate Bayesian Computation (ABC) and an extension where I embedded ABC into an MCMC framework.

This talk is part of the Computational and Systems Biology series.

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