University of Cambridge > Talks.cam > Three-dimensional cell culture: Innovations in tissue scaffolds and biomimetic systems > Advanced Membrane Bioartificial Systems for the Development of Tissues and Organs

Advanced Membrane Bioartificial Systems for the Development of Tissues and Organs

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  • UserDr. Loredana De Bartolo, National Research Council of italy Institute on Membrane Technology, CNR-ITM, Rende, Italy
  • ClockWednesday 08 February 2017, 11:15-11:45
  • HouseOnline.

If you have a question about this talk, please contact Ilana Spilka.

Micro- and nano-structured membranes designed and operated according to well-defined engineering criteria are able to sustain cellular specific functions, to provide adequate mass transfer of molecules throughout the cellular compartment and to supply appropriate biomechanical stimuli of the developing tissue. In this paper the author shows bioinspired approaches such as those related to the use of different tailor-made bioengineered membrane systems using liver cells, stem cells, neuronal cells, and keratinocytes. Membrane bioreactors may simulate the in vivo complex physiological environment ensuring an adequate mass transfer of nutrients and metabolites and the molecular and mechanical regulatory signals. Membrane bioreactors developed to create a liver organotypic system and a neuronal network with defined functional, geometric and neuroanatomical features will be presented.

This talk is part of the Three-dimensional cell culture: Innovations in tissue scaffolds and biomimetic systems series.

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