University of Cambridge > Talks.cam > Plant Sciences Departmental Seminars > Sustainable bioenergy and biofuels from microalgae: a systems biology perspective

Sustainable bioenergy and biofuels from microalgae: a systems biology perspective

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Microalgae have great potential as a biofuel feedstock, and the conditions that stimulate lipid biosynthesis (the precursors of biofuels) have been investigated extensively in the last few decades. One of the widely used triggers for microalgal lipid production is Nitrogen limitation/starvation in the culture medium. However, the use of this trigger is associated with a reduction in cell growth which leads to lipid productivities lower than those necessary for the development of efficient industrial exploitations. In the BBSRC -funded India-UK project “Sustainable bioenergy and biofuels from microalgae: a systems biology perspective (SuBB)” we aimed to overcome this caveat through a systems biology study. In this presentation, results from two of the research lines developed during the project will be discussed. On the one hand, I will talk about the optimization of lipid productivity in industrially relevant microalgal species by manipulating culture conditions following approaches from the industrial engineering field. On the other hand, I will present results from the study of the metabolic regulatory mechanisms involved in the lipid biosynthesis of the microalgae Phaeodactylum tricornutum. To address this we focused on investigating the cascade of changes of the metabolic response at the transcriptomic, proteomic and metabolic levels during the early stages of nitrogen deprivation, and how these were related to later changes in microalgal physiology.

This talk is part of the Plant Sciences Departmental Seminars series.

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