Biochemical Calculations 

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Renal Calculations 
Creatinine Clearance Calculated Creatinine Clearance (Cockcroft & Gault) Online Calculator (umol/L) Calculated Creatinine Clearance (Lean Body Mass est'd from height) Online Calculator (umol/L) Fractional Excretion of Sodium (FENA) Creatinine Clearance  correction for body surface area


General Calculations 
LDL Cholesterol Transferrin Saturation Indirect Bilirubin Calcium corrected for albumin 
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Renal Calculations

Creatinine Clearance (calculated from creatinine measured in 24 hours urine and plasma collections) Creatinine Clearance (mL/s) = {U Creat x Vol x 1000} / {Pl Creat x Time x 60 x 60} Urine and plasma creatinine concentrations in mmol/L; Volume in mL For serum creatinine measurements in umol/L: Creatinine Clearance (mL/s) = {U Creat x Vol x 1000 x 1000} / {Pl Creat x Time x 60 x 60} Urine creatinine concentration in mmol/L and serum creatinine concentrations in umol/L; Volume in mL
Notes: Calculated Creatinine Clearance (Cockcroft and Gault) (estimated from plasma creatinine, age, wt and sex) Creatinine Clearance (mL/s) = {(140  Age)} x Wt x F}/ {P CREAT x 48816} F= 1 (males); F=0.85 (females) For serum creatinine measurements in umol/L: Creatinine Clearance (mL/s) = {(140  Age)} x Wt x F}/ {P CREAT x 48.816} F= 1 (males); F=0.85 (females)
Notes: (estimated from plasma creatinine, age, height and sex) Creatinine Clearance (mL/s) = {(140  Age)} x Wt x F}/ {P CREAT x 48816} F= 1 (males); F=0.85 (females) For serum creatinine measurements in umol/L: Creatinine Clearance (mL/s) = {(140  Age)} x Wt x F}/ {P CREAT x 48.816} F= 1 (males); F=0.85 (females)
Estimated Lean Body Mass from patient's height: Notes: Fractional Excretion Of Sodium (FENA) FENA(%) = {U Na / Pl Na x 100} / {U Cr / Pl Cr} All concentrations in mmol/L Interpretation: Creatinine Clearance Per M^{2} Body Surface Area (BSA) BSA(m^{2}) = 0.0235 x Ht(cm)^{0.42246} x wt(kg)^{0.51456} CrCl(mL/s/1.73m^{2}) = U CRCL(mL/s) x 1.73/BSA(m^{2}) 

General Calculations 
LDLC (mmol/L) = Total Cholesterol  HDLCholesterol  (Triglycerides / 2.2) All values in mmol/L Notes: %SAT = 3.982 x Iron (umol/L) / Transferrin (g/L) Indirect Bilirubin (umol/L) = Total Bilirubin (umol/L)  Direct Bilirubin (umol/L) Indirect bilirubin is a measure of unconjugated bilirubin Used to correct plasma total calcium measurements for effects of changes in albumin concentration. Corrected calcium can then be compared with usual reference intervals. Calcium (corrected, mmol/L) = Calcium (measured, mmol/L) + {(40  albumin (g/L)) x 0.02} Notes:


Last Updated 16/12/2004 
