University of Cambridge > Talks.cam > The Anatomical Basis of Disease (2nd February 2009, Hinxton)

The Anatomical Basis of Disease (2nd February 2009, Hinxton)

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INTRODUCTION

In the study of human biology and in clinical practice, the concept of anatomy unifies a number of scientific, engineering and biomedical disciplines.

This meeting will present efforts by the Virtual Physiological Human (VPH) community, as well as other specialities, to model human structure and its function. This event also aims to advance the computational unification of anatomy in biological and pharmacological databases, physiological models, radiological images and clinical records.

Updates on key research in academia and industry will include the modelling of concepts (e.g. disease ontologies), structures (e.g. biochemical compartments, volumetric data) and processes (e.g. pharmacokinetics, blood pressure regulation). Ways to foster the interoperability of such modelling methods will also be explored, together with approaches to improve access to clinical phenotypic data for basic research.

This event sets the stage for establishing a community toolkit for the rigorous representation of human anatomy and the close study of its dynamic change in physiology, its orchestrated moulding in development, and its distortion in disease.

The meeting is divided into four sessions: 1) Concepts of Anatomy and Disease (chair: Lynn Schriml, University of Maryland). 2) Organizing anatomical models (chair: Bernard de Bono, EMBL -EBI). 3) Modeling anatomical physiology (chair: Dan Cook, University of Washington School of Medicine). 4) Bridging across anatomical scales (chair: Jesper Tenger, Karolinska Institute).

VENUE AND REGISTRATION

The venue for this meeting is the Francis Crick Auditorium at the Wellcome Trust Conference Centre (http://www.wtconference.org.uk/).

This meeting is hosted by EMBL -EBI and sponsored by EMBL -EBI (Industry Programme) and VPH Network of Excellence (http://www.vph-noe.eu/) with funding from the European Commission. There is no charge for attendance, howewer, delegates must register in advance.

If you would like to attend please email Liz Ford (ford@ebi.ac.uk) stating your name, affiliation and whether you would use transport between Cambridge and Hinxton on the day, if available. CLOSING DATE FOR REGISTRATIONS IS 21st JANUARY 2009 .

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Closing remarks

UserBernard de Bono (EMBL-EBI).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 17:30-18:00

Achieving multi-scale interoperability of VPH data and models

UserBernard de Bono (EMBL-EBI).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 17:00-17:30

Towards global pharmacodynamics - predicting the compartmental location of proteins

UserThomas Skot-Jensen (Technical University of Denmark, DTU).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 16:30-17:00

Interoperability across resources via anatomy

UserJonathan Bard (Weatherall Institute, Oxford).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 16:00-16:30

Multi-scale modelling in musculoskeletal mechanics

UserMarco Viceconti (Rizzoli Institute).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 14:00-14:30

FieldML - a standard for anatomically based physiological modelling

UserPeter Hunter (University of Auckland).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 12:30-13:00

Volumetric annotation of mouse anatomy

UserDuncan Davidson (MRC, Edinburgh).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 12:00-12:30

Statistical models of radiological anatomy

UserAlex Frangi (University Pompeu Fabra).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 11:30-12:00

Integrating data and models using the Disease Ontology

UserWarren Kibbe (NorthWestern University).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 10:30-11:00

Connecting to clinical data - mapping SNOMED to anatomy

UserKent Spackman (IHTSDO).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 10:00-10:30

The Foundational Model of Anatomy

UserOnard Mejino (University of Washington School of Medicine).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 09:30-10:00

Welcome and Introductions

UserDominic Clark (EMBL-EBI), Janet Thornton (EMBL-EBI), Peter Coveney (UCL), Bernard de Bono (EMBL-EBI).

HouseFrancis Crick Auditorium, WTGC.

ClockMonday 02 February 2009, 09:00-09:30

Registration and Tea/Coffee

UserWellcome Trust Conference Centre.

Househttp://www.wtconference.org.uk/.

ClockMonday 02 February 2009, 08:30-09:00

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