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The Anatomical Basis of Disease (2nd February 2009, Hinxton)
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INTRODUCTION In the study of human biology and in clinical practice, the concept of anatomy unifies a number of scientific, engineering and biomedical disciplines. This meeting will present efforts by the Virtual Physiological Human (VPH) community, as well as other specialities, to model human structure and its function. This event also aims to advance the computational unification of anatomy in biological and pharmacological databases, physiological models, radiological images and clinical records. Updates on key research in academia and industry will include the modelling of concepts (e.g. disease ontologies), structures (e.g. biochemical compartments, volumetric data) and processes (e.g. pharmacokinetics, blood pressure regulation). Ways to foster the interoperability of such modelling methods will also be explored, together with approaches to improve access to clinical phenotypic data for basic research. This event sets the stage for establishing a community toolkit for the rigorous representation of human anatomy and the close study of its dynamic change in physiology, its orchestrated moulding in development, and its distortion in disease. The meeting is divided into four sessions: 1) Concepts of Anatomy and Disease (chair: Lynn Schriml, University of Maryland). 2) Organizing anatomical models (chair: Bernard de Bono, EMBL -EBI). 3) Modeling anatomical physiology (chair: Dan Cook, University of Washington School of Medicine). 4) Bridging across anatomical scales (chair: Jesper Tenger, Karolinska Institute). VENUE AND REGISTRATION The venue for this meeting is the Francis Crick Auditorium at the Wellcome Trust Conference Centre (http://www.wtconference.org.uk/). This meeting is hosted by EMBL -EBI and sponsored by EMBL -EBI (Industry Programme) and VPH Network of Excellence (http://www.vph-noe.eu/) with funding from the European Commission. There is no charge for attendance, howewer, delegates must register in advance. If you would like to attend please email Liz Ford (ford@ebi.ac.uk) stating your name, affiliation and whether you would use transport between Cambridge and Hinxton on the day, if available. CLOSING DATE FOR REGISTRATIONS IS 21st JANUARY 2009 . If you have a question about this list, please contact: Dominic Clark. If you have a question about a specific talk, click on that talk to find its organiser. 0 upcoming talks and 15 talks in the archive. Closing remarksBernard de Bono (EMBL-EBI). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 17:30-18:00 Achieving multi-scale interoperability of VPH data and modelsBernard de Bono (EMBL-EBI). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 17:00-17:30 Towards global pharmacodynamics - predicting the compartmental location of proteinsThomas Skot-Jensen (Technical University of Denmark, DTU). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 16:30-17:00 Interoperability across resources via anatomyJonathan Bard (Weatherall Institute, Oxford). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 16:00-16:30 Virtual organisms in the prediction of pharmacokinetics – principles and applicationsSimon Thomas (Cyprotex Ltd). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 15:00-15:30 Multi-scale modelling of kidney function in the context of blood pressure regulation and fluid homeostasisRandy Thomas (CNRS). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 14:30-15:00 Multi-scale modelling in musculoskeletal mechanicsMarco Viceconti (Rizzoli Institute). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 14:00-14:30 FieldML - a standard for anatomically based physiological modellingPeter Hunter (University of Auckland). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 12:30-13:00 Volumetric annotation of mouse anatomyDuncan Davidson (MRC, Edinburgh). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 12:00-12:30 Statistical models of radiological anatomyAlex Frangi (University Pompeu Fabra). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 11:30-12:00 Integrating data and models using the Disease OntologyWarren Kibbe (NorthWestern University). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 10:30-11:00 Connecting to clinical data - mapping SNOMED to anatomyKent Spackman (IHTSDO). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 10:00-10:30 The Foundational Model of AnatomyOnard Mejino (University of Washington School of Medicine). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 09:30-10:00 Welcome and IntroductionsDominic Clark (EMBL-EBI), Janet Thornton (EMBL-EBI), Peter Coveney (UCL), Bernard de Bono (EMBL-EBI). Francis Crick Auditorium, WTGC. Monday 02 February 2009, 09:00-09:30 Registration and Tea/CoffeeWellcome Trust Conference Centre. http://www.wtconference.org.uk/. Monday 02 February 2009, 08:30-09:00 Please see above for contact details for this list. |
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