The ins and outs of mitochondrial protein quality control

Professor Dr Christian Münch.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 10 April 2024, 15:00-16:00

Targeting liver mitochondria to treat MASLD/MASH and cardiometabolic disease

Professor Gerald Shulman.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 20 March 2024, 15:00-16:00

Unravelling the impact of membrane transporters in cancer drug uptake and efficacy

Dr Louise Fets MRC Investigator CRUK Career Establishment Awardee Drug Transport and Tumour Metabolism Lab Medical Research Council Laboratory of Medical Sciences (LMS).

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 07 February 2024, 15:00-16:00

Mitochondria dynamics and metabolism regulate species-specific features of human brain development

Professor Pierre Vanderhaeghen | VIB-KU Leuven Center for Brain & Disease Research, Belgium.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 13 December 2023, 15:00-16:00

Focusing on mitochondria with super-resolution microscopy

Professor Stefan Jakobs | Max Planck Institute, Germany.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 15 November 2023, 15:00-16:00

The (in)fidelity of human mitochondrial gene expression

Professor Brendan Battersby, University of Helsinki, Finland.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Tuesday 14 November 2023, 15:00-16:00

Biological energy transduction in action - deciphering the molecular mechanism of the remarkable Complex I

Professor Ville Kaila | Stockholm University.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 01 November 2023, 15:00-16:00

Mitochondrial fusion in neural stem cell differentiation in Drosophila development

Professor Richa Rikhy, Indian Institute of Science Education and Research (IISER), Pune, India.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 18 October 2023, 15:00-16:00

Selective autophagy as a mechanism of oxidative stress response

Dr Viktor Korolchuk | Faculty of Medical Sciences, Newcastle University.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 04 October 2023, 15:00-16:00

From Bench to Patients; Decanoic/Octanoic Acid & Brain Energy Metabolism

Professor Simon Heales | University College London .

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 13 September 2023, 15:00-16:00

Unbiased Genetic Screening to find Modifiers of Mitochondria in Neurons

Dr Gaynor Smith | Cardiff Univeristy.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 28 June 2023, 15:00-16:00

Signal Switches at the Mitochondrial Import Machinery

Professor Chris Meisinger | Institute for Biochemistry and Molecular Biology, University of Freiburg.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 10 May 2023, 15:00-16:00

Subcellular renovation: shaping of the mitochondrial inner-membrane

Professor Luke Chao | Havard Medical School.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 03 May 2023, 15:00-16:00

Curbing mitochondrial dysfunction in neurodegeneration: lessons from neurogenetics

Dr Derek Narendra | National Institute of Neurological Disorders and Stroke.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Tuesday 25 April 2023, 15:00-16:00

Remodeling of Mitochondria during Microbial Infection

Dr Lena Pernas | MPI, Cologne.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 05 April 2023, 15:00-16:00

ER stress and mitochondria 

Professor Giovanna Mallucci | Founding Principal Investigator, Altos Labs Cambridge Institute of Science, Cambridge UK.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 01 March 2023, 15:00-16:00

The Wonders of Small Molecule Transport

Professor David Drew | Stockholm University .

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 15 February 2023, 15:00-16:00

Patterns underlying the mitochondrial life cycle

Professor Sulina Manley, Laboratory of Experimental Biophysics - EPFL .

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 07 December 2022, 15:00-16:00

The 8th Annual Sir John Walker Lecture

Nikolaus Pfanner - Professor and Chair of Biochemistry Institute of Biochemistry and Molecular Biology, University of Freiburg, Germany.

The Max Perutz Lecture Theatre, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH.

Thursday 01 December 2022, 16:00-17:00

How is mtDNA transcription regulated?

Professor Nils-Göran Larsson, Karolinska Institute .

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Thursday 24 November 2022, 15:00-16:00

Rescuing mitochondria in peril under oxidative stress

Professor Kostas Tokatlidis | University of Glasgow.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 23 November 2022, 15:00-16:00

Dual transport function of mitochondrial uncoupling proteins

Professor Elena Pohl | University of Veterinary Medicine, Vienna .

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 16 November 2022, 15:00-16:00

The Parkinson’s disease protein LRRK2 regulates the transition from innate to adaptive immunity by modulating the unfolded protein response

Professor Michel Desjardins, University of Montreal.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Monday 31 October 2022, 15:00-16:00

Identifying the network of bactericidal interactions between mycobacterial respiratory chain complexes to develop fast-acting drugs for tuberculosis

Professor Gregory M. Cook, University of Otago, New Zealand.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Tuesday 11 October 2022, 15:00-16:00

POSTPONED - Cdk12 maintains the axon initial segment through actin remodelling

POSTPONED - new date tbc

Dr Gaynor Smith | Cardiff University.

MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

Wednesday 05 October 2022, 15:00-16:00

Does mitochondria metabolism regulate apoptosis?

Professor Atan Gross, Weizmann Institute.

Contact organiser for details.

Wednesday 03 August 2022, 15:00-16:00

Phenotype-based approaches to rare disease diagnostics and discovery in the 100,000 Genomes Project & Whole genome sequencing in suspected mitochondrial disorders

Professor Damian Smedley & Dr Katherine Schon.

Contact organiser for details.

Wednesday 13 July 2022, 15:00-16:00

Mitochondrial Na+ import by the Na+/Ca2+ exchanger NCLX regulates the electron transport chain and ROS production

Dr Antonio Martínez-Ruiz, Hospital Univ. Santa Cristina, Instituto de Investigación Sanitaria Princesa (IIS Princesa), Madrid.

Contact organiser for details.

Tuesday 05 July 2022, 15:00-16:00

Mitochondria: portrait of an inflammatory killer

Professor Stephen Tait | Beatson Institute.

Online (Zoom) - contact organiser for details.

Wednesday 22 June 2022, 15:00-16:00

Mitochatting - new insights into mitochondrial contact sites uncovered from systematic analysis of contact site proteomes

Professor Maya Schuldiner | Weizmann Institute of Sciences, Israel.

Online (Zoom) - contact organiser for details.

Wednesday 25 May 2022, 15:00-16:00

How mycobacteria subvert mitochondrial biology to casue TB

Professor Lalita Ramakrishnan | MRC Laboratory of Molecular Biology .

Online (Zoom) - contact organiser for details.

Wednesday 04 May 2022, 15:00-16:00

Building a Culture of Research Integrity

Dr Rhys Morgan | Head of Research Policy, Governance and Integrity, University of Cambridge.

Online (Zoom).

Wednesday 20 April 2022, 15:00-16:00

Exploring the role of mitochondria in Parkinson’s disease

Professor Sonia Gandhi | UCL.

Online (Zoom).

Wednesday 09 March 2022, 15:00-16:00

Science Publishing and Publishing in Science

Dr Stella M Hurtley | Deputy Editor, Science .

Online (Zoom).

Wednesday 23 February 2022, 15:00-16:00

Enhancing recombinant protein production in Escherichia coli

Professor Jan-Willem de Gier | Stockholm University.

Online (Zoom) - details tbc.

Wednesday 19 January 2022, 15:00-16:00

“How mitochondria control immune T cell killing"

Professor Gillian Griffiths | Cambridge Institute for Medical Research.

Online (Zoom) - details tbc.

Wednesday 12 January 2022, 15:00-16:00

Title to be confirmed

Dr Stephen Tait | CRUK Beatson Institute / University of Glasgow .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 21 October 2020, 15:00-16:00

Title to be confirmed

Dr Kostas Tokatlidis | University of Glasgow .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 07 October 2020, 15:00-16:00

Title to be confirmed

Professor Chris Meisinger | Institute for Biochemistry and Molecular Biology, Germany.

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 24 June 2020, 15:00-16:00

Title to be confirmed

Professor Antonio Zorzano | Institute for Research in Biomedicine, Barcelona.

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 10 June 2020, 15:00-16:00

Title to be confirmed

Professor Leonid Sazanov | Institute of Science and Technology, Austria.

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 13 May 2020, 15:00-16:00

Arterial redox signalling in the control of bood pressure under inflammatory conditions

Professor Roland Stocker | Victor Chang Cardiac Research Institute, Australia .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Thursday 13 February 2020, 15:30-16:30

Viscosity and macromolecular crowding affects size-dependent protein diffusion and conformation in the mitochondrial matrix

Dr Werner Koopman | Radbound Centre for Mitochondrial Medicine .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 27 November 2019, 15:00-16:00

Mutation-free cells prevent transmission of mtDNA disease and enable new treatment options

Professor Bert Smeets | Maastricht University.

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 20 November 2019, 15:00-16:00

Molecular basis of mitochondrial DNA replication in mammalian cells

Prof Maria Falkenberg | University of Gothenburg .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Tuesday 12 November 2019, 16:00-17:00

Fitness selection in the early mouse embryo: how differences in mitochondrial activity trigger cell competition

Dr Tristan Rodriguez | Imperial College London .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 30 October 2019, 15:00-16:00

Mitochondrial DNA maintenance in non-standard model systems

Professor Torsten Ochsenreiter | University of Bern .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 16 October 2019, 15:00-16:00

The fidelity of human mitochondrial gene expression

Dr Brendan Battersby | University of Helsinki.

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Thursday 10 October 2019, 15:00-16:00

How PINK1- and Parkin-mediated Mitophagy Prevents Neurodegeneration

Dr Richard J. Youle | National Institute of Neurological Disorders and Stroke .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 02 October 2019, 15:00-16:00

Paracoccus denitrificans oxidative phosphorylation, retentions, gains, losses, and lessons en route to mitochondria

Professor Stuart Ferguson | University of Oxford .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 25 September 2019, 15:00-16:00

Achieving Redox Signalling specificity through Spatiotemporal and Chemical approaches

Dr Tobias Dansen | UMC Utrecht .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 11 September 2019, 15:00-16:00

Nutrition sensing pathways regulate transmission of mutant mitochondrial genomes

Dr Maulik Patel | Vanderbilt University .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Monday 29 July 2019, 14:00-15:00

Mitochondrial membrane musings

Dr Steven Claypool | John Hopkins University, Baltimore USA.

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 17 July 2019, 15:00-16:00

Mitochondrial dynamics in muscle physiopathology

Professor Marco Sandri | University of Padova, Italy .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 03 July 2019, 15:00-16:00

A 'proton ratchet' couples the membrane potential to protein secretion (and perhaps also mitochondrial protein import)

Professor Ian Collinson | University of Bristol .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 19 June 2019, 15:00-16:00

Mitochondria and Hypoxia Signalling

Professor Margaret Ashcroft | Dept. of Medicine, University of Cambridge.

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Tuesday 11 June 2019, 15:00-16:00

Mitochondria and acute oxygen sensing by arterial chemoreceptors

Professor José López Barneo | Instituto de biomedicina de Sevilla .

Sackler Lecture Theatre (Level 7) The Keith Peters Building, Cambridge Biomedical Campus.

Wednesday 29 May 2019, 15:00-16:00

Exploring new roles for ER-mitochondria organelle contacts in neurons

Professor Franck Polleux | Columbia University .

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Thursday 11 April 2019, 15:00-16:00

Proteomic exploration of the scope, dynamics, and stoichiometry of lysine acetylation

Prof. Chunaram Choudhary | University of Copenhagen .

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 10 April 2019, 15:00-16:00

Mitochondrial Disease in Australian Children – genomics, epidemiology and functional validation

Professor David Thorburn | MCRI .

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Tuesday 26 March 2019, 15:00-16:00

Haplogroup context is a key element to deciding if an mtDNA variant is a mutation or population polymorphism, complete study of mitochondrial tRNA’s across multiple taxa

http://www.newcastle-mitochondria.com/joanna-elson/

Dr Joanna Elson | Wellcome Centre for Mitochondrial Research, Newcastle University.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 20 March 2019, 15:00-16:00

Sex, Heterochromatin and Disease

Professor Richard Festenstein - Imperial College London .

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 27 February 2019, 15:00-16:00

From dyfunction of the PINK1/Parkin pathway to Parkinson’s disease

Dr Olga Corti | ICM, Paris .

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 06 February 2019, 15:00-16:00

Mitochondrial biogenesis: dynamic complexes for a dynamic organelle

Professor Mike Ryan | Monash Biomedicine Discovery Institute .

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Thursday 31 January 2019, 15:00-16:00

Management of mitochondrial proteins: sort or destroy

Professor Agnieszka Chacinska.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Thursday 17 January 2019, 15:00-16:00

Origin of Native Americans: a paradigmatic case in human population studies

Antonio Torroni, University of Pavia.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 28 November 2018, 15:00-16:00

Mito-nuclear interactions and mitochondrial replacement therapy: an evolutionary perspective

Professor Adam Eyre-Walker, University of Sussex.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 21 November 2018, 15:00-16:00

Cross-Species Genetic Mapping of Targets in Mitochondria, Metabolism and Aging

Professor Johan Auwerx, EPFL, Lausanne.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 07 November 2018, 11:00-12:00

Understanding the molecular basis for drug and nutrient transport across the membrane.

Professor Simon Newstead, University of Oxford.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Tuesday 16 October 2018, 15:00-16:00

Title to be confirmed

Dr Erika L Pearce, Max Planck Institute of Immunology and Epigenetics, Freiburg.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 03 October 2018, 15:00-16:00

Cryo-EM structures of the mitochondrial calcium uniporters

Rozbeh Baradaran, Sloan Kettering Institute .

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Tuesday 18 September 2018, 15:00-16:00

Thyroid hormone regulation of autophagy: A therapeutic strategy for NAFLD

Professor Paul M Yen, Duke-NUS Medical School, Singapore.

Seminar room 3.37, Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Monday 17 September 2018, 12:00-13:00

Mitochondrial dysfunction and signalling in the nervous system

Dr Joseph Bateman, Kings College London.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 12 September 2018, 11:00-12:00

Molecular mechanisms of reversible infantile mitochondrial diseases

Professor Rita Horvath, Newcastle University.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Friday 27 July 2018, 15:00-16:00

Tissue-specific aspects of heteroplasmy in human mitochondrial DNA

Professor Mark Stoneking, Max Planck Institute for Evolutionary Anthropology, Leipzig.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 18 July 2018, 15:00-16:00

Spatial organisation of mitochondrial gene expression: the role of mitochondrial RNA granules

Professor Jean-Claude Martinou, University of Geneva.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 04 July 2018, 15:00-16:00

Title to be confirmed

Professor Heidi McBride, McGill University, Montreal, Canada.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Friday 29 June 2018, 15:00-16:00

Revealing mitochondrial function by reading mtDNA mutation patterns

Dr James Stewart, Max Planck Institute for Biology of Ageing, Cologne, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 20 June 2018, 15:00-16:00

Whole genome sequencing for diagnosis and discovery of mitochondrial diseases

Professor Anna Wedell, Karolinska Institute, Sweden.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Tuesday 05 June 2018, 15:00-16:00

Organelle-specific subcellular delivery using miothcondria-penetrating peptides

Professor Shana Kelly, University of Toronto.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 30 May 2018, 15:00-16:00

Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production

Professor Andrew Larner, Virginia Commonwealth University.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 02 May 2018, 15:00-16:00

Title to be confirmed

Professor Thomas Meier, Imperial College London.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 18 April 2018, 15:00-16:00

A role for actin in mitochondrial division: effects across two membranes

Professor Henry Higgs, Geisel School of Medicine, Dartmouth College, NH.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Tuesday 17 April 2018, 15:00-16:00

Drosophila models of mitochondrial toxic signals

Dr L Miguel Martins, MRC Toxicology Unit, Leicester.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 14 March 2018, 15:00-16:00

The 6th Annual Sir John Walker Lecture, 'Genomics approaches to mitochondrial physiology and disease'

There will be a reception at 17:30.

Vamsi K Mootha MD, HHMI and Harvard Medical School, USA.

Max Perutz Lecture Theatre, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus.

Thursday 22 February 2018, 16:30-17:30

m1A modification of nuclear- and mitochondria-encoded mRNA: Rare, dynamic and potent

Dr Schragi Schwartz, Weizmann Institute, Israel.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 24 January 2018, 15:00-16:00

Molecular wiring of a mitochondrial translation feedback loop

Professor Martin Ott, Stockholm University.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Tuesday 12 December 2017, 15:00-16:00

Isotope tracing, flux analysis and the metabolic phenotypes of transformed cells

Professor Roland Nilsson, Karolinska Institute.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 29 November 2017, 15:00-16:00

Title to be confirmed

Professor William Martin, Institute of Molecular Evolution, Duesseldorf.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 22 November 2017, 15:00-16:00

AMPK - a sensor of cellular energy and glucose availability, and a key interface between mitochondria and their host cell

Professor Grahame Hardie, University of Dundee.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 15 November 2017, 15:00-16:00

Exploring molecular mechanisms in biological energy conversion

Professor Ville Kaila, Technical University of Munich.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 01 November 2017, 15:00-16:00

Title to be confirmed

Professor Jean Claude Martinou, University of Geneva.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 06 September 2017, 15:00-16:00

Title to be confirmed

Professor David Thorburn, Murdochs Childrens Research Institute, Victoria, Australia.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Friday 16 June 2017, 15:00-16:00

Title to be confirmed

Professor Aleksandra Filipovska, University of Western Australia.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Tuesday 06 June 2017, 15:00-16:00

Oxidative stress, ROS and free radicals - using nitroxide antioxidants for detection and protection

Professor Steve Bottle, University of Queensland, Australia.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 31 May 2017, 15:00-16:00

The 5th Annual Sir John Walker Lecture, "The mitochondrial calcium uniporter: molecular identity and physiological role"

Professor Rosario Rizzuto, University of Padova, Italy.

Max Perutz Lecture Theatre, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus.

Thursday 11 May 2017, 16:30-17:30

Eating your mitochondria: why, when and where?

Dr Ian Ganley, The MRC Protein Phosphorylation and Ubiquitylation Unit, Dundee University.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 26 April 2017, 15:00-16:00

Title to be confirmed

Dr Atan Gross, Weizmann Institute of Science, Rehovot, Israel.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 19 April 2017, 15:00-16:00

"There's something wrong with my MAM; the ER-mitochondria axis and neurodegenerative diseases"

Professor Christopher Miller, King's College London.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Cambridge Biomedical Campus.

Wednesday 05 April 2017, 15:00-16:00

Title to be confirmed

Professor Dame Linda Partridge, Institute of Healthy Ageing, UCL.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 07 December 2016, 15:00-16:00

Mitochondrial disease research at Queen Square - past, present and future

Dr Robert Pitceathley, UCL London.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Tuesday 22 November 2016, 15:00-16:00

Title to be confirmed

Professor Claes Gustafsson, University of Gothenburg.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 19 October 2016, 15:00-16:00

Title to be confirmed

Dr Nick Jones, UCL London.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 12 October 2016, 15:00-16:00

Title to be confirmed

Dr Henna Tyynisma, University of Helsinki.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 05 October 2016, 15:00-16:00

Structure, Biology and Therapeutic Potential of Novel ER Located Growth Factors

Professor Mart Saarma, Institute of Biotechnology, Helsinki.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 28 September 2016, 15:00-16:00

Using electron microscopy to study mitochondrial ribosomes

The 4th Annual Sir John Walker Lecture

Sir Venkatraman Ramakrishnan, MRC LMB.

Max Perutz Lecture Theatre, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus.

Thursday 15 September 2016, 16:30-17:30

Biogenesis of iron-sulfur proteins in eukaryotes: Mitochondria, mitoses, mechanisms, DNA maintenance, and maladies

Professor Roland Lill, Institute for Cytobiology and Cytopathology, Marburg.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 14 September 2016, 15:00-16:00

Adaptations mediated by a mitochondrial UPR

Dr Cole Haynes, Memorial Sloan Kettering Cancer Center, New York.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Thursday 08 September 2016, 15:00-16:00

Title to be confirmed

Dr Miratul Muqit, MRC Protein Phosphorylation and Ubiquitylation Unit, Dundee.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 07 September 2016, 15:00-16:00

Title to be confirmed

Professro Luca Scorrano, The Venetian Institute of Molecular Medicine.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 20 July 2016, 15:00-16:00

Evolution and coordination of the mitochondrial protein synthesis machinery

Professor Lluis Ribas, Institute for Research in Biomedicine, Barcelona.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 13 July 2016, 15:00-16:00

The transparent editorial process, data reproducibility and research integrity at EMBO Press

Dr Roberto Buccione, EMBO.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 29 June 2016, 15:00-16:00

Natural and engineered redox signaling relays inside and outside mitochondria

Professor Tobias Dick, German Cancer Research Center.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 15 June 2016, 15:00-16:00

Regulation of mitochondrial function by stearic acid

Professor Aurelio Teleman, German Cancer Research Center.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 08 June 2016, 15:00-16:00

Mitochondrial optic neuropathies and beyond: the common theme of mitochondrial dynamics and mechanistic insights

Dr Valerio Carelli, Department of Biomedical and Neuromotor Sciences, University of Bologna.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 01 June 2016, 15:00-16:00

The Wanderings of a Free Radical

Professor Barry Halliwell, National University of Singapore.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 25 May 2016, 15:00-16:00

Mitochondrial Proteases and Neurodegeneration

Dr Thomas Langer, Institute for Genetics, University of Cologne.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 11 May 2016, 15:00-16:00

Title to be confirmed

Professor Martin Picard, Columbia University, New York.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 27 April 2016, 15:00-16:00

Intermediate steps of the respirasome assembly pathway: Gaining insight into the structural interdependences among respiratory chain complexes

Dr Christine Ugalde, Instituto de Investigacion Sanitaria, Madrid, Spain.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 20 April 2016, 15:00-16:00

The exome sequencing identified the mutation in YARS2 Nuclear modifier genes for the phenotypic manifestation of Leber's hereditary optic neuropathy-associated mitochondrial DNA mutation

Professor Min Xin Guan, Director, Institute of Genetics, Zhejiang University, China.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 06 April 2016, 15:00-16:00

ROS produced via Reverse Electron Transport at respiratory complex I regulates mitochondrial turnover and lifespan

Dr Alberto Sanz, Ageing Research Laboratories, Newcastle University.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 16 March 2016, 15:00-16:00

Our journey towards mouse models of mitochondrial DNA disease

Dr James Stewart, Max Planck Institute for Biology of Ageing.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 09 March 2016, 15:00-16:00

CoQ Redox Status is a Metabolic Sensor

Dr Jose Antonio Enriquez, Fundacion CNIC, Spain.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 24 February 2016, 15:00-16:00

Between life and death: A dual function for the mitochondrial F-ATP synthase

Professor Paolo Bernardi, University of Padova, Italy.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Tuesday 02 February 2016, 15:00-16:00

Mitigating mitochondrial mutational meltdown

Professor Patrick Chinnery, University of Cambridge and MRC MBU.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 28 October 2015, 15:00-16:00

Mitochondria at work: Regulation of skeletal muscle mitochondria function during exercise

Jorgen Jensen, School of Clinical Medicine, University of Cambridge.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 21 October 2015, 15:30-16:30

The Third Annual Sir John Walker Lecture: "HUMAN OBESITY: CAUSES AND CONSEQUENCES"

Professor Stephen O'Rahilly, University of Cambridge.

Max Perutz Lecture Theatre, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus.

Monday 28 September 2015, 16:30-17:30

Mitochondrial remodelling during embryonal cancer stem cell differentiation

Dr Paulo Jorge Silva Oliveira, University of Coimbre, Portugal.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 15 July 2015, 15:00-16:00

Molecular and pharmacological regulation of cell mitophagy

Dr Michelangelo Campanella, Royal Veterinary College, UCL.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 01 July 2015, 15:00-16:00

Molecular regulation of receptor-mediated mitochondrial autophagy and its role in aging related diseases

Professor Quan Chen, The State Key Laboratory of Membrane Biology, Chinese Academy of Sciences.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Monday 29 June 2015, 15:00-16:00

TBA

Professor Dr Wolfram Kunz, University of Bonn, Germany.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 17 June 2015, 15:00-16:00

TBA

Dr Alexander Galkin, Queens University, Belfast.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 03 June 2015, 15:00-16:00

The alternative oxidase: a novel therapeutic target for the treatment of trypanosomiasis, cryptosporidiosis and candidiasis

Professor Anthony Moore, University of Sussex.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 27 May 2015, 15:00-16:00

The structure and mechanism of mitochondrial complex I

Professor Ulricht Brandt, Radboud University, Nijmegen, NL.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 20 May 2015, 15:00-16:00

Molecular strategies for monitoring and controlling mitochondria

Dr Richard Hartley, University of Glasgow.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 13 May 2015, 15:00-16:00

Targeted nanoparticles for mitochondrial medicine

Dr Shanta Dhar, University of Georgia, USA.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 29 April 2015, 15:00-16:00

Markus: From its origins to the modern metabolic network. Jakob: Overcoming the yeast ‘petite’ phenotype: Insights into metabolic adaptations to mitochondrial genome loss

Dr Markus Raiser and Dr Jakob Vowinckel, University of Cambridge.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 22 April 2015, 15:00-16:00

tRNase ZL (ELAC 2) is central to eukaryotic pre-tRNA 3' end maturation

Professor Louis Levinger, City University New York, USA.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 08 April 2015, 15:00-16:00

Mitochondrial evolution: genome vs proteome

Professor Michael Gray, Dalhousie University, Canada.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Friday 27 March 2015, 15:00-16:00

Structure and mechanism of mitochondrial cytochrome c oxidases

Professor Peter Rich, University College London.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 25 March 2015, 15:00-16:00

Tracking proton pathways in the heme-copper oxidase superfamily: Insights from all-atom simulations

Dr Andrei Pisliakov, University of Dundee.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 11 March 2015, 15:00-16:00

The role of mammalian CLpP protease beyond mitochondrial unfolded protein response

Professor Aleksandra Trifunovic, CECAD Research Centre, Cologne, Germany.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 04 March 2015, 15:00-16:00

Biogenesis of mitochondrial membrane protein complexes

Professor Peter Rehling, Max Planck Institute for Biophysical Chemistry, Gottingen, Germany.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 25 February 2015, 15:00-16:00

Who is talking with who in hte OXPHOS system, and how?

Dr Jose Antonio Enriquez Dominguez, CNIC, Madrid.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 11 February 2015, 15:00-16:00

Mitochondrial complex I assembly; regulating the metabolic regulator

Dr Leo Nijtmans, Nijmegen Centre for Mitochondrial Disorders.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 04 February 2015, 15:00-16:00

Title to be confirmed

Professor Juan Bolanos, University of Salamanca-CSIC, Spain.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 10 December 2014, 15:00-16:00

Mitochondrial optic neuropathies as a multifaceted model for neurodegeneration: a reappraisal

Dr Valerio Carelli, University of Bologna, Italy.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Thursday 27 November 2014, 15:00-16:00

Translation machinery in mitochondria – from structure towards clinic

Dr Alexey Amunts, MRC Laboratory of Molecular Biology, Cambridge.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 26 November 2014, 15:00-16:00

The 2nd Annual Sir John Walker Lecture: "Bioenergetic constraints on the evolution of cells"

Dr Nick Lane, University College London.

Max Perutz Lecture Theatre, MRC LMB.

Monday 24 November 2014, 16:30-17:30

Mitochondria and hypoxia/HIF signalling

Professor Margaret Ashcroft, University of Cambridge.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Tuesday 18 November 2014, 15:00-16:00

UCP2 regulates the oxidation of glucose and glutamine by exporting C4 metabolites out of mitochondria

Professor Giuseppe Fiermonte, University of Bari, Italy.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 29 October 2014, 15:00-16:00

Exome sequencing in the paediatric mitochondrial clinic

Dr Shamima Rahman, UCL Institute of Child Health.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 10 September 2014, 15:00-16:00

Modeling GBA1-associated Parkinson's disease using engineered pluripotent stem cells

Michela Deleidi, University of Tuebingen, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Tuesday 10 June 2014, 15:00-16:00

Translational bioenergetics in diabetes; from the beta cell to chronic kidney disease

Victor M Darley-Usmar, PhD, University of Alabama at Birmingham.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 04 June 2014, 15:00-16:00

Metabolite damage and its repair or pre-emption

Professor Andrew Hanson, University fo Florida, USA.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Tuesday 20 May 2014, 15:00-16:00

'Coping with cellular stress: the mitochondrial way'

Dr Gyorgy Szabadkai, UCL.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Thursday 24 April 2014, 15:00-16:00

Mitochondrial gene expression in humans: a tale of two tails

Professor Robert Lightowlers, Newcastle University.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 23 April 2014, 15:00-16:00

p73 regulates cancer cell survival and metabolism

Professor Gerry Melino, University of Leicester.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 16 April 2014, 15:00-16:00

Molecular mechanisms and therapeutic approaches to childhood mitochondrial diseases

Professor Rita Horvath,Institute of Human Genetics - Newcastle University.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 09 April 2014, 15:00-16:00

Alternative respiratory enzymes: a route to therapy for mitochondrial disorders

Professor Howy Jacobs, University of Tampere, Finland.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 12 March 2014, 15:00-16:00

Insights into mitochondrial disease using polymerase gamma disease as a paradigm

Professor Laurence Bindoff, University of Bergen, Norway.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 19 February 2014, 15:00-16:00

Physiological and pharmacological activation of AMP-activated protein kinase

Professor David Carling, MRC Clinical Sciences Centre.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 29 January 2014, 15:00-16:00

Analysis of Parkinson's disease genes using Drosophila: mitophagy and axonal transport

Professor Alex Whitworth, University of Sheffield.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 22 January 2014, 15:00-16:00

Molecular mechanisms of mitochondrial genetic disease

Professor Robert Taylor, Newcastle University.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 15 January 2014, 15:00-16:00

The mitochondrial m-AAA protease and neurodegeneration

Professor Elena Rugarli, University of Cologne.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 11 December 2013, 15:00-16:00

TBA

Dr Elizabeth Murchison, Wellcome Trust Sanger Institute, Cambridge UK.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 27 November 2013, 15:00-16:00

TBA

Professor Brendan Battersby, University of Helsinki, Finland.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 13 November 2013, 15:00-16:00

Reading the (mitochondrial) signals to understand tissue-specific pathology

Dr Nuno Raimundo, PhD Institute for Cellular Biochemistry Universitatsmedizin, Goettingen, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 23 October 2013, 15:00-16:00

THE INAUGURAL SIR JOHN WALKER LECTURE: 'A Mitochondrial Etiology of Metabolic and Degenerative Diseases, Cancer and Aging'

Dr Douglas Wallace, Center for Mitochondrial and Epigenomic Medicine (CMEM), Children's Hospital of Philadelphia, USA.

The Martin Cohen Lecture Theatre, CRUK, Cambridge Research Institute, Cambridge.

Tuesday 15 October 2013, 16:30-17:30

Posttranscriptional regulation of mitochondrial gene expression

Dr Eric Shoubridge, McGill University, Montreal, Canada.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Monday 30 September 2013, 15:00-16:00

'Mitochondria in cell fate reprogramming: from mechanisms to disease investigation'

Dr Alessandro Prigione, Max Delbrueck Center for Molecular Medicine, Berlin, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Friday 07 June 2013, 15:00-16:00

'The mitochondrial permeability transition pore: A mystery solved?'

Professor Paolo Bernardi, Venetian Institute of Molecular Medicine, Padova, Italy.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Tuesday 28 May 2013, 15:30-16:30

'Pantothenate kinase-associated neurodegeneration: investigations of a Pank2 KO mouse model and development of new neuronal cellular systems'

Dr Valeria Tiranti, IRCCS Foundation Institute of Neurology "C. Besta", Milan, Italy.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 15 May 2013, 15:00-16:00

Regulation of complex I amount: molecular mechanism

Professor José Antonio Enriquez, CNIC, Spain.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Thursday 02 May 2013, 15:00-16:00

Supercomplex assembly determines electron flux in the mitochondrial electron transport chain

Professor José Antonio Enriquez, CNIC, Spain.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 01 May 2013, 15:00-16:00

The power and limits of NGS strategies to address mitochondrial disorders

Dr Holger Prokisch, Helmholtz Zentrum Muenchen.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Tuesday 09 April 2013, 14:30-15:30

Protein structure determination using X-ray lasers

Professor Henry Chapman, University of Hamburg, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 06 March 2013, 15:00-16:00

'Mitochondrial dysfunction modifies physiological signaling and contributes to pathogenesis'

Professor Anu Somalainen-Wartiovaara, University of Helsinki, Finland.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 27 February 2013, 15:00-16:00

'Genetics and biotechnological applications at high temperature'

Professor Jose Berenguer, Universidad Autonoma de Madrid, Spain.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 30 January 2013, 15:00-16:00

'Adapting to unfolded protein load in the endoplasmic reticulum'

Professor David Ron, University of Cambridge.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 23 January 2013, 15:00-16:00

Mitochondrial transcription and its regulation

Professor Claes Gustafsson, University of Gothenburg.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 16 January 2013, 15:00-16:00

'Mitochondria: from pyruvate import to RNA processing'

Professor Jean-Claude Martinou, University of Geneva.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 05 December 2012, 15:00-16:00

Exome sequencing in mitochondrial disorders as a tool to advance our understanding of mitochondrial physiology

Dr Holger Prokisch, Hemholtz Centre Munich, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 28 November 2012, 15:00-16:00

Metabolism and cancer: why should we care?

Professor Eyal Gottlieb, University of Glasgow.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 21 November 2012, 15:00-16:00

The metabolic transformation of cancer cell

Dr Christian Frezza, MRC Cancer Cell Unit, Cambridge.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 07 November 2012, 15:00-16:00

Physio-pathology of mitochondrial complex III assembly

Dr Erika Fernandez-Vizarra.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 17 October 2012, 15:00-16:00

Mitochondria and the cytoskeleton – matters of life and death in the face of stress

Dr Campbell Gourlay, University of Kent.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 10 October 2012, 15:00-16:00

'Co-operative switching, turnover, and mechano-chemistry in a biological macromolecular complex'

Dr Richard Berry, University of Oxford.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 20 June 2012, 15:00-16:00

'Exploitation of host mitochondria by human pathogenic Neisseria'

Professor Thomas Rudel, Biozentrum, University of Wuerzburg, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 23 May 2012, 15:00-16:00

'Neurodegenerative alpha-synucleinopathies'

Dr Maria Grazia Spillantini, University of Cambridge.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 16 May 2012, 15:00-16:00

'Parkinson's disease: is it all mitochondrial?'

Professor Nicholas Wood, UCL Institute of Human Genetics and Health.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 09 May 2012, 15:00-16:00

'Coupling of Na+/H+ transfer to the rotary mechanism of ATP synthase'

Dr Thomas Meier, Max-Planck Institute of Biophysics, Frankfurt, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 25 April 2012, 15:00-16:00

'The making of mitochondrial complex I: regulation of the biogenesis of a key metabolic enzyme'

Dr Leo Nijtmans, NCMLS, Radboud University, Nijmegen, The Netherlands.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 04 April 2012, 15:00-16:00

'Clustering of Alpers disease mutations and catalytic defects in biochemical variants'

Professor Laurie Kaguni, Michigan State University, USA.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 21 March 2012, 15:00-16:00

'Atomic structures of the eukaryotic ribosome and implications for the initiation of protein synthesis'

Professor Nenad Ban, Institute of Molecular Biology & Biophysics, ETH Zurich.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 14 March 2012, 15:00-16:00

‘Multiscale simulations of membrane proteins and their interactions’

Professor Mark Sansom, University of Oxford.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 08 February 2012, 15:00-16:00

'Neurodegenerative tauopathies'

Dr Michel Goedert, MRC Laboratory of Molecular Biology, Cambridge, UK.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 25 January 2012, 15:00-16:00

'Evolutionary and functional relationships between eukaryotes and mitochondria'

Professor Martin Embley, Newcastle University.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 18 January 2012, 15:00-16:00

'Metabolic clocks'

Dr Akhilesh Reddy, University of Cambridge.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 14 December 2011, 15:00-16:00

'Synaptic damage in neurodegeneration'

Professor Perluigi Nicotera, The German Centre for Neurodegeneration (DZNE), Bonn, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 07 December 2011, 15:00-16:00

'Three-dimensional electron microscopy of cells and viruses at molecular resolution: From structure to mechanism'

Professor Sriram Subramaniam, National Cancer institute Center for Cancer Research, Bethesda, MD, USA.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 07 December 2011, 12:00-13:00

'The respiratory complex I: substrate binding sites and mechanism of proton translocation'

Professor Thorsten Friedrich, University of Freiburg, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 16 November 2011, 15:00-16:00

'PGC-1α in muscular and neurodegenerative disorders'

Dr Tina Wenz, University of Cologne, Germany.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 09 November 2011, 15:00-16:00

'ATP-sensitive potassium channels and neonatal diabetes: a treatable channelopathy'

Professor Frances Ashcroft, University of Oxford.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 02 November 2011, 15:00-16:00

'Molecular characterization of the mitochondrial calcium uniporter'

Professor Vamsi Mootha, Harvard Medical School, USA.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Friday 21 October 2011, 15:00-16:00

'UCP1 and the other "uncoupling proteins": regulation and significance'

Professor Barbara Cannon, Stockholm University, Sweden.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 12 October 2011, 15:00-16:00

'The mitochondria's role in autophagy and cell cycle control'

Professor Jennifer Lippincott-Schwartz, National Institutes of Health, Bethesda, USA.

Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

Thursday 29 September 2011, 15:00-16:00

'L-form bacteria, mitochondria, and the origins of cellular life'

9th Annual Sir William Dunn Lecture

Professor Jeff Errington, University of Newcastle.

Max Perutz Lecture Theatre, MRC Laboratory of Molecular Biology (Addenbrooke's Site).

Monday 13 June 2011, 16:30-17:30

Mitochondrial Reactive Oxygen Species: Signals or Stresses?

Professor Paul Schumacker, Northwestern University, Chicago, USA.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 23 March 2011, 15:00-16:00

Mitochondrial optic neuropathies as a multifaced model for neurodegeneration

Professor Valerio Carelli, University of Bologna, Italy.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 16 March 2011, 15:00-16:00

'Mitochondrial release factors: a family or just good friends?'

Dr Zofia Chrzanowska-Lightowlers, University of Newcastel.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 02 February 2011, 15:00-16:00

'Imaging mitochondrial function in the intact heart'

Dr Alexander Lyon, National Heart and Lung Institute, Imperial College.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Thursday 27 January 2011, 15:00-16:00

'What mitochondria learned from their bacterial ancestors: Oxidation-driven protein folding'

Professor Johannes Herrmann, University of Kaiserslautern, Germany.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 19 January 2011, 15:00-16:00

'Disulfide bond formation in biogenesis of mitochondrial proteins'

Professor Agnieszka Chacinska, International Institute of Molecular and Cell Biology, Poland.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 15 December 2010, 15:00-16:00

'Modelling and analysis of diabetes-related metabolic processes'

Dr John Hancock, MRC Harwell.

Sackler Lecture Theatre (Level 7), Wellcome Trust/MRC Building, Addenbrooke's Site.

Wednesday 08 December 2010, 15:00-16:00