cri


2007-03-08 16:15: Structural variation in the human genome (Matthew Hurles, Wellcome Trust Sanger Institute, Cambridge)

2007-03-13 16:15: Quantitative proteomics of organelles of the early secretory pathway (John Bergeron, McGill University, Montreal, Canada)

2007-03-21 14:15: Receptor-recruitment by a natively disordered protein (Colin Kleanthous, University of York)

2007-03-29 16:15: Ubiquitin signalling networks (Ivan Dikic, Goethe University Medical School, Frankfurt)

2007-04-03 13:00: Title to be confirmed (Speaker to be confirmed)

2007-04-12 16:15: The molecular mechanics of eukaryotic translation initiation (Jon Lorsch, John Hopkins, Baltimore)

2007-04-17 12:00: Title to be confirmed (Michael Wakelam, Babraham Institute)

2007-04-19 13:00: Breast Cancer (Daniel Birnbaum, Départment d'Oncologie Moléculaire, Institut de Cancérologie de Marseille)

2007-04-24 12:00: RNAi Functional Analysis of Drug Resistance Pathways (Charlie Swanton, Cancer Research UK London Research Institute)

2007-04-24 16:15: LepA, one of the most conserved proteins known and present in all bacteria and mitochondriae, is a ribosomal elongation factor with a new function (Knud Nierhaus, Max Planck Institute for Molecular Genetics, Berlin)

2007-05-01 12:00: Dimethyl sulfoxide to vorinostat-targeted histone deacetylase inhibitor – mechanisms of action as an anti-cancer drug (Paul Marks, Sloan-Kettering Institute, New York)

2007-05-08 12:00: Germline genetic predictors of prognosis in breast cancer (Paul Pharoah, Department of Oncology, Strangeways Research Laboratories)

2007-05-10 16:15: Neural Processing of Optic Flow in the Fly (Alex Borst, MPI of Neurobiology, Martinsried)

2007-05-15 12:00: Experimental cancer medicine at the Dana Farber Cancer Institute (Lee Nadler, Dana Farber Cancer Institute, Boston, USA)

2007-05-16 16:15: Optogenetic control of neuronal function, and molecular analysis of nicotinic acetylcholine receptor associated proteins in Caenorhabditis elegens (Alex Gottschalk, Universit of Frankfurt)

2007-05-17 13:00: Lymphocyte Development (Amanda Fisher, MRC Clinical Sciences Centre, London)

2007-05-17 16:15: Centrosomes: organizers of cell division in C.elegans embryos (Tony Hyman, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden)

2007-05-22 16:15: Structural Analysis of Glutamate receptor gating and allosteric regulation (Mark Mayer, NIH, Bethesda)

2007-05-29 12:00: Molecular heterogeneity of breast cancer - biological and clinical implications (Carlos Caldas, CRUK Cambridge Research Institute)

2007-05-31 16:15: Mechanisms of epigenetic reprogramming in mammalian development (Wolf Reik, Babraham Institute, Cambridge)

2007-06-04 16:15: Evolution of the Pathological process underlying sporadic Parkinson's Disease (Heiko Braak, University of Frankfurt)

2007-06-05 12:00: Novel mechanisms of clinical drug resistance in ovarian cancer (James Brenton, CRUK Cambridge Research Institute)

2007-06-12 12:00: Towards a fuller understanding of inherited susceptibility to colorectal cancer (Richard Houlston, Institute of Cancer Research, Sutton)

2007-06-13 09:30: A tool of developmental biology for understanding tumorigenesis (Shin-ichi Ohnuma, Hutchison/MRC Research Centre, Dept of Oncology.)

2007-06-19 12:00: Exploiting senescence and anoikis in function-based oncogenomic screens (Daniel Peeper, Netherlands Cancer Institute)

2007-06-19 16:15: Organising Microtubules in Space and Time (Damien Brunner, EMBL Heidelberg)

2007-06-21 13:00: Human Sarcomas - Prostate and Bladder Cancers (Colin Cooper, Male Urological Cancer Research Centre Institute of Cancer Research)

2007-06-26 12:00: Developments in radiotherapy: new treatments for today and tomorrow (Neil Burnet, Deptartment of Oncology)

2007-06-27 09:30: Chromatin modifying enzymes and their involvement in cancer (Luke Hughes-Davies, Department of Oncology)

2007-07-03 16:15: HIV assembly - is it the plasma membrane after all? (Mark Marsh, MRC LMCB)

2007-07-04 09:30: Introduction to chemotherapy: role of Kaplan Meier curves in clinical cancer research (Luke Hughes-Davies, Department of Oncology)

2007-07-17 12:00: Targeting RET kinase activity as a novel therapeutic strategy for medullary thyroid carcinoma (Francesca Carlomagno, University of Naples)

2007-07-19 13:00: Role of NCOA4 protein in controlling DNA replication (Francesca Carlomagno, Università di Napoli Federico II, Naples, Italy)

2007-07-26 13:00: Oncogenes and Tumor Suppressors: The Good, The Bad and The Ugly (Gerard Evan, University of California, San Fransisco Comprehensive Cancer Center)

2007-08-08 16:15: Searching for biological function and evolutionary trajectories in the protein universer (Dr L Aravind, National Center for Biotechnology Information, NIH, USA)

2007-09-04 12:00: "Targeting the Met receptor for cancer therapy" (Ermanno Gherardi) and "Preclinical efforts in Pancreatic Cancer" (Dave Tuveson) (Ermanno Gherardi (MRC Laboratory of Molecular Biology) and Dave Tuveson (CRUK Cambridge Research Institute))

2007-09-04 16:15: What structural studies tell us about amyloids and prions (Professor David Eisenberg, HHMI?UCLA-DOE Institute for Genomics and Proteomics, Los Angeles, USA)

2007-09-11 12:00: Molecular genetics of MALT lymphoma: application in diagnosis and prognosis (Prof Ming Du), tbc (Prof Robert Marcus) (Robert Marcus (Addenbrooke's Hospital) and Ming Du (University of Cambridge Department of Pathology))

2007-09-13 13:00: Centrosome cycle, cell division and chromosome segregation (Erich Nigg, Max Planck Institute of Biochemistry)

2007-09-18 12:00: Title to be confirmed (David Baulcombe, Sainsbury Lab, Norwich)

2007-09-21 12:00: Regulation of the proteasome and the dynamics of multiubiquitin chains (Prof Dan Finley, Dept. of Cell Biology, Harvard Medical School, Boston, USA)

2007-10-04 13:00: Viruses as gene therapy vectors (Inder Verma, Laboratory of Genetics, Salk Institute)

2007-10-09 12:00: Proteins that license DNA replication (Laskey) Clinical exploitation of proteins that license DNA replication (Coleman) (Ron Laskey and Nick Coleman (Hutchison-MRC Research Centre))

2007-10-23 12:00: Gain-of-function JAK2 mutations in the human myeloproliferative disorders (Linda Scott (Cambridge Institute for Medical Research))

2007-10-26 11:00: Genomics: From Humans to the Environment (Dr Craig Venter)

2007-11-01 11:15: Silence of the Genes:  DNA methylation in cancer (Dr Howard Cedar)

2007-11-01 16:15: Structural basis of interative fatty acid synthesis catalyzed by giant multienzyme complexes (Dr Nenad Ban)

2007-11-06 16:15: RNA Structure, Catalysis and the Origin of Lfe (Dr Bill Scott)

2007-11-13 12:00: "High throughput mapping of cis-regulatory DNA elements: From genomic arrays to functional biology" (George Follows) & "Rapid evolutionary turnover of transcription factor binding" (Duncan Odom) (George Follows (Cambridge Institute for Medical Research) and Duncan Odom (CRUK Cambridge Research Institute))

2007-11-13 16:15: Organisation of membrane transport by microtubule motors and plus tracking proteins (Dr Anna Akhmanova)

2007-11-15 13:00: Sequencing Mammalian Epigenomes (Tarjei Mikkelsen, Broad Institute, Massachusetts Institute of Technology)

2007-11-19 15:00: The Role of Epithelial Stem Cells in Inherited and Acquired Diseases (Dennis Roop, Charles C. Gates Chair in stem cell biology, School of Medicine, University of Colorado)

2007-11-20 12:00: Title to be confirmed (Margaret Stanley, Department of Pathology)

2007-11-20 16:15: The DNA damage problem and its impact on cancer and aging (Dr Jan Hoeijmakers)

2007-11-23 16:15: Microfluidics in Biology (Dr Ronny van't Oever)

2007-11-27 12:00: Progress in prostate cancer and the androgen receptor (David Neal and Ian Mills, CRUK Cambridge Research Institute)

2007-12-04 12:00: Searching for and confirming common breast cancer risk alleles (Dunning) Update on Diet and Breast Cancer (Bingham) (Alison Dunning & Sheila Bingham, Department of Oncology & MRC Dunn Human Nutrition Unit)

2007-12-11 16:15: ENCODE: Understanding our genome (Dr Ewan Birney)

2007-12-13 16:15: Turning LMB Science into a Half a Billion Dollar Business (Dr Ian Tomlinson)

2007-12-18 12:00: Beyond VEGF: vascular signaling targets for therapeutic manipulation (David Quinn, University of Southern California)

2008-01-22 12:00: Acute Myeloid Leukaemia: Molecular Pathogenesis, Prognostication and Targeted therapy (Brian Huntly) (Brian Huntly (Department of Haematology, Cambridge Institute of Medical Research) & Charles Crawley (Oncology Department, Addenbrookes Hospital))

2008-01-24 13:00: Mouse Model for Cancer Biology (Scott Lowe, Cold Spring Harbor Laboratory)

2008-01-29 12:00: "Computational biology and cancer: the CRI perspective" and "Lung Cancer: A New Strategy" (Simon Tavaré, CRUK Cambridge Research Institute and Tim Eisen, Medical Oncologist (Lung and Renal cancer), Addenbrooke's Hospital)

2008-01-31 09:30: Ubiquitin / proteasome mediated protein degradation (Laura Itzhaki, MRC Cancer Cell Unit, MRC-Hutchison Research Centre)

2008-01-31 16:15: Feldberg Foundation Prize Lecture: "Formation of ribonucleoprotein particles and their nuclear export through nuclear pore complexes (Dr Ed Hurt, University of Heidelberg)

2008-02-04 13:00: G-quadruplex Nucleic Acids: Non-coding Elements with Function? (Shankar Balasubramanian, University of Cambridge)

2008-02-07 16:15: Towards in vivo molecular automata (Dr Yaakov Benenson, Bauer Fellow, FAS Center for Systems Biology, Harvad University)

2008-02-12 12:00: Imaging biology in the cancer patient (K. Brindle) (Kevin Brindle (CRUK Cambridge Research Institute and Department of Biochemistry) and Athar Ahmad (Medical Oncologist, Colorectal Tumours), Addenbrooke's Hospital)

2008-02-19 12:00: Title to be confirmed (Stefanie Reichelt (CR UK Cambridge Research Institute) and Sara Booth (Palliative Care), Addenbrooke's Hospital)

2008-02-21 13:00: New Pathways of Tumour Agiogenesis and Hypoxia Response (Adrian Harris, Weatherall Institute of Molecular Medicine, Oxford)

2008-02-25 16:15: RNA catalysis: sophisticated biochemistry by a simple biopolymer (Dr Adrian Ferre D'Amare, Fred Hutchinson Cancer Research Center, Seattle)

2008-02-26 12:00: Experimental manipulation of the epidermis to study normal and cancer stem cells and The GIST of GISTS (Gastrointestinal Stromal tumours) (Fiona Watt, CRUK Cambridge Research Institute and Ramesh Bulusu, Clinical Oncologist (Lung/Upper GI/Lymphoma), Addenbrooke's Hospital)

2008-02-28 16:15: Autophagy and neurodegenerative diseases (Prof David Rubinsztein, Cambridge Institute for Medical Research)

2008-03-04 10:30: Biomarker Studies in Barrett's Esophagus and Esophageal Adenocarcinoma (Stephen Meltzer, Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center)

2008-03-06 16:15: Centrosomal delivery of secretory granules (Prof Gillian Griffiths, Cambridge Institute for Medical Research)

2008-03-07 12:00: Functional Heterogeneity of Mouse Hematopoietic Stem Cells (Brad Dykstra, University Medical Center Groningen, The Netherlands)

2008-03-07 14:15: How do miRNAs silence gene expression? (Dr Elisa Izaurralde, Department of Biochemistry, Max-Planck-Institute for Developmental Biology)

2008-03-11 12:00: Title to be confirmed (Paul Pharoah (Strangeways Research Laboratories) and Rajesh Jena (Addenbrooke's Hospital)))

2008-03-13 12:00: Understanding the self-renewal ability of mouse embryonic stem (ES) cells through single cell mRNA and microRNA profiling approach (Fuchou Tang, The Wellcome Trust/Cancer Research UK Gurdon Institute)

2008-03-14 14:15: Structure and Dynamics of the Human beta 2 Adrenergic Receptor (Professor brian Kobilka)

2008-03-18 12:00: 'Monitoring anticancer drug uptake by magnetic imaging and spectroscopy' and 'Breast cancer heterogeneity- a clinical challenge' (John Griffiths (CRUK Cambridge Research Institute) and Carlos Caldas (CRUK Cambridge Research Institute))

2008-03-18 16:15: Targeting the lipid kinases (Dr Zachary Knight)

2008-03-25 12:00: Title to be confirmed (Ermanno Gherardi (MRC Laboratory of Molecular Biology) and Helena Earl (Medical Oncologist; Sarcoma, breast and ovarian cancer), Addenbrooke's Hospital))

2008-03-27 13:00: Proteins and Pathways Involved in Tumorigenicity (Jackie Lees, Massachusetts Institute of Technology)

2008-04-03 16:15: A glimpse into the atomic structure of plant photosystem I - 3.5 billion years of perfection (Professor Nathan Nelson)

2008-04-08 10:30: Using Chemical Tools to Elucidate the Molecular Mechanism of Malaria Infection and Develop a Malaria Vaccine (Professor Peter Seeberger)

2008-04-08 12:00: Breast Cancer Heterogeneity and the Cancer Stem Cell Hypothesis (John Stingl, Cambridge Research Institute)

2008-04-10 16:15: The organization and topology of the bacterial nucleoid: steps towards a holistic theory of transcriptional regulation (Professor Georgi Muskhelishvili)

2008-04-11 16:15: Using microfluidics to ask other peoples questions in biology (Dr Mark Tracey)

2008-04-15 12:00: Title to be confirmed (Hugo Ford, Addenbrooke's Hospital)

2008-04-22 12:00: Chromosome translocations and gene fusions in breast cancer and Improving outcomes in melanoma: a fresh look (Paul Edwards (Hutchison/MRC Research Centre) and Pippa Corrie (Addenbrooke's Hosptial, Clinical Oncologist, Lung and Upper GI Cancer))

2008-04-24 13:00: Cancer Epigenetics (Peter Laird, University of Southern California)

2008-04-24 16:15: The interplay between phosphorylation and polyubiquitinatioan in regulating the innate immune system (Professor Sir Philip Cohen)

2008-04-29 12:00: Targeting Hyperactive Ras and Uncovering Mechanisms of Therapeutic Resistance in Genetically Engineered Mice (Kevin Shannon, University of California San Francisco)

2008-05-01 16:15: A "molecular sled" activates the adenovirus proteinase and carries it along tens of thousands of base pairs of viral DNA via one-dimensional diffusion to locate its substrates (Dr Walter Mangel)

2008-05-06 16:15: Transcription factories and nuclear organization of the genome (Dr Peter Fraser)

2008-05-13 12:00: TBC (Adele Murrell, CRUK Cancer Research Institute and TBC)

2008-05-20 12:00: TBC (Phil Jones, MRC Cancer Cell Unit, Hutchison-MRC Research Centre and Kate Fife, Addenbrooke's Hospital)

2008-05-27 12:00: Trials and Tribulations in the Management of Head and Neck Cancer (Sarah Jefferies, Addenbrooke's Hospital)

2008-06-09 13:00: Taming Glioblastoma -Targeting Angiogenesis (CRI Special Seminar) (Dr Steve Brem, Moffitt Cancer Center)

2008-06-09 16:15: Function of diverse transcriptional coactivators in animal cells (Professor Robert G Roeder)

2008-06-10 12:00: 'Mechanisms of tamoxifen action and resistance' and 'Cambridge  Oncology - Past, Present & Future: A tour from the 18th to 21st Century' (Jason Carroll, CRI and David Gilligan, Addenbrooke's Hospital)

2008-06-17 12:00: Using Bayesian analysis in randomised phase II clinical trials to determine the worth of proceeding to phase III (Cindy Billingham, University of Birmingham)

2008-06-24 12:00: TBC (Gill Murphy, CRI and Charles Wilson, Addenbrooke's Hospital)

2008-06-25 16:15: Structural analysis of cells and viruses at molecular resolution with 3D electron microscopy (Dr Sriram Subramaniam)

2008-07-04 16:15: Understanding and controlling cell death (Professor Jim Wells)

2008-07-10 16:15: Novel molecular switches for optical research on living cells (Dr Gerard Marriott)

2008-07-29 13:00: New Insight into the Cause(s) of Prostate Cancer (Brian E. Henderson, Keck School of Medicine, University of Southern California)

2008-08-22 11:15: Connectomics in the developing nervous system (Professor Jeff W Lichtman)

2008-09-02 12:00: Chromatin modifying enzymes: their function and role in cancer (Tony Kouzarides, WT/CRUK Gurdon Institute)

2008-09-03 12:00: Special seminar: Analysing the dynamic glycome (Lara Mahal, University of Texas, Austin)

2008-09-08 13:00: Use of cell-context-specific molecular interaction maps to identify master regulators of malignant transformations (Andrea Califano, Herbert Irving Comprehensive Cancer Center, Columbia University)

2008-09-16 12:00: Early phase clinical trials in Cambridge (Duncan Jodrell, Cambridge Research Institute and Department of Oncology)

2008-09-16 16:15: The structure of tubulin and the control of microtubule assembly (Professor Marcell Knossow)

2008-09-23 12:00: Title to be confirmed (Nick Carroll, Department of Radiology)

2008-09-25 16:15: SNAREs, Synaptotagmin, and Fusion Pores (Professor Meyer Jackson)

2008-09-30 12:00: Title to be confirmed (Richard Benson, Addenbrooke's Hospital)

2008-10-06 16:15: eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA (Dr Leos Valasek)

2008-10-10 14:30: Tackling an old enemy: new ways to target RNA (Dr Gabriele Varani)

2008-10-14 12:00: High-throughput cancer cell line screening: a tool for discovery (Ultan McDermott, Massachusetts General Hospital Cancer Center and Harvard Medical School)

2008-10-22 14:00: Fascin Protrusions in ECM-Cytoskeletal Networking and Metastasis (Josephine Adams, Lerner Research Institute, Cleveland)

2008-10-28 12:00: The role of Fam38 in integrin activation and lung cancer (Tariq Sethi, Chair of Respiratory and Lung Cancer Biology, Centre for Inflammation Research, University of Edinburgh)

2008-11-04 16:15: Identification of 20 novel breast cancer fusion genes using genome-wide massively parallel paired-end sequencing (Dr Philip Stephens)

2008-11-06 09:30: Mechanisms of DNA replication (Nick Robinson, MRC Cancer Cell Unit, Hutchison/MRC Centre)

2008-11-06 16:15: Thinking Small: Fragment-Based Drug Design (Dr Glyn Williams)

2008-11-11 12:00:  The West Anglia CLRN, TCRNs and the Coordinated System for gaining NHS Permission – How is it all going to work? (Lena Pettersson, Lead RM and G Manager, West Anglia NIHR CLRN)

2008-11-13 13:00: The Editorial Process Demystified (Andrew Sugden, International Managing Editor, Science Magazine)

2008-11-18 12:00: Colorectal neoplasia: what we know and don't know about genes and environment (John Potter, Fred Hutchinson Cancer Research Centre)

2008-11-20 16:15: Cancerous microRNAs and regulatory binding proteins (Dr Reuven Agami)

2008-11-21 16:15: CANCELLED - Transcriptional regulation by the Polycomb system (Dr Juerg Mueller)

2008-11-24 16:15: Insights into mechanosensitive ion channels (Professor Jim Naismith)

2008-11-25 12:00: The role of developmental biology in cancer research (Anna Philpott and Shin-ichi Ohnuma, Department of Oncology, MRC-Hutchison Research Centre)

2008-12-02 12:00: Delineating the Fanconi Anaemia DNA repair defect (KJ Patel, MRC Laboratory of Molecular Biology)

2008-12-03 09:30: Tumour suppressors 1 and 2 (Ashok Venkitaraman & Dave Tuveson; Hutchison/MRC Research Centre & Cambridge Research Institute)

2008-12-09 12:00: Title to be confirmed (Rebecca Fitzgerald, Cancer Cell Unit, Hutchison/MRC Research Laboratory)

2008-12-09 16:15: Love at first light (Professor Gero Miesenboeck)

2008-12-11 13:00: Microsignalosomes: Spatially Resolved Receptor-Signalling (Facundo Batista, Cancer Research UK, London Research Institute)

2008-12-12 11:15: DNA sequence dynamics under nucleosome constraint: Form Follows Function Follows Form? (Professor Andrew Fire)

2008-12-15 11:00: IgH Class switching, Translocations, and Lymphoma (Professor Fred Alt)

2009-01-06 12:00: Patterns of stem and progenitor cell fate in adult tissues (Professor Ben Simons, Department of Physics, Cambridge University)

2009-01-20 12:00: The evidence for lifestyle after cancer to reduce relapse and survival (Robert Thomas, Addenbrooke's Hospital)

2009-01-22 13:00: Regulation of self-renewal in cancer stem cells (Pier Pelicci, Department of Experimental Oncology, European Institute of Oncology, Milan)

2009-01-26 16:15: Nuclear architecture in zebrafish: Cajal bodies are required for life and splicing during embryogenesis (Dr Karla Neugebauer)

2009-01-27 12:00: Sarcomas and the insulin-like growth factor pathway (Robert Maki, Memorial Sloan-Kettering Research Center)

2009-01-27 16:15: Multidimensional proteomics and genetic analysis reveal condensin's function in vertebrate mitotic chromosomes (Dr Bill Earnshaw)

2009-02-03 12:00: Role of the c-Myc-target gene Misu (NSun2) in regulating epidermal stem cell fate and its implications for cancer (Michaela Frye, Wellcome Trust Centre for Stem Cell Research, University of Cambridge)

2009-02-05 16:15: Indecent exposure: replication, sex and survival with unprotected telomeres (Dr Julia Cooper)

2009-02-10 12:00: Clinical potential of functional ion channel expression in cancer (Mustafa Djamgoz, Imperial College London)

2009-02-10 16:15: Disease, development, evolution and environment: insights from eyes (Professor Veronica van Heyningen)

2009-02-19 13:00: Skin Development: Making Tissues from Stem Cells (Elaine Fuchs, Howard Hughes Medical Institute, The Rockefeller University)

2009-02-19 16:15: From cell mechanics to tissue morphogenesis (Dr Thomas Lecuit)

2009-02-24 12:00: The role of cyclin-kinase inhibitors in the development of cancer (Nisar Malek, Hannover Medical School, Germany)

2009-02-24 16:15: Activation of Protein Kinases by the HSP90 Molecular Chaperone System (Dr Laurence Pearl)

2009-02-26 09:30: Genetic association studies to find common disease susceptibility alleles (Alison Dunning, Strangeways Research Laboratories)

2009-03-03 12:00: The spatial organisation of Ras signaling (Philippe Bastiaens, Max Planck Institute of Molecular Physiology, Germany)

2009-03-10 12:00: Radiation-induced bowel damage:  let's put right what is wrong (Jervoise Andreyev, Royal Marsden Hospital)

2009-03-12 09:30: Intestinal cancer models and stem cell biology (Doug Winton, CRUK Cambridge Research Institute)

2009-03-12 16:15: New work with RNase P: regulation in HeLa cells and therapeutic tools (Professor Sidney Altman)

2009-03-13 14:00: Regulators of synapse formation in C. elegans (Professor Kang Shen)

2009-03-17 12:00: Outreach chemotherapy programme (Pippa Corrie, Addenbrooke's Hospital)

2009-03-19 13:00: The adenomatous polyposis protein as a cytoskeletal architect: implications for early tumourigenesis (Inke Näthke, University of Dundee)

2009-03-24 12:00: What comes after cancer stem cells? (Doug Winton, CRUK Cambridge Research Institute)

2009-03-26 16:15: The Nature and Chemical Biology of G-quadruplex Nucleic Acids (Professor Shankar Balasubramanian)

2009-03-27 16:15: Modern synthetic biology.  Darwin from the atom up (Professor Steven A Benner)

2009-03-31 12:00: Analysis of early events after DNA damage in living cells; the HP1 paradigm (Anand Jeyasekharan, Hutchison/MRC Research Centre)

2009-03-31 16:15: X-ray tomography generates 3-D views of whole cells at better than 50 nm resolution (Dr Carolyn Larabell, University of California)

2009-04-07 12:00: Connecting Lung Epithelial Stem Cells and Lung Cancer by Stress-Activated Protein Kinases (Juan Jose Ventura, Wellcome Trust Centre for Stem Cell Research, University of Cambridge)

2009-04-21 12:00: Preservation of fertility in patients with cancer (Raj Mathur (Addenbrooke's Hospital) and Tom Mathews (Medical Director, Bourn Hall))

2009-04-23 09:30: Stem cells and cancer (epithelial cancers) (Fiona Watt, CRUK Cambridge Research Institute)

2009-04-23 11:00: Nanotubes and Synapses in Immune Cell Biology (Professor Daniel Davis, Imperial College London)

2009-04-28 12:00: OPCML in Tumour Gene Therapy in Ovarian Cancer (Hani Gabra, Faculty of Medicine, Imperial College London)

2009-04-30 12:00: Genetic analysis of Parkinson disease; from fruit flies to moving mitochondria (Alex Whitworth-Department of Biomedical Science, The University of Sheffield)

2009-05-01 14:30: Probing dynamic assembly and conformational changes of GPCR signalling complexes using bioluminescence and fluorescence resonance energy transfer approaches. (Professor Michel Bouvier-Institute for Reseach in Immunology and Cancer, Université de Montréal)

2009-05-05 12:00: Taming the tiger by the tail:  modulation of DNA damage responses by telomeres (David Lydall, Institute for Ageing and Health, Newcastle University)

2009-05-07 09:30: Assessing responses to cancer therapy using molecular imaging magnetic resonance methods (Kevin Brindle and John Griffiths, CRUK Cambridge Research Institute)

2009-05-14 09:30: Inherited susceptibility to cancer (Bruce Ponder, CRUK Cambridge Research Institute)

2009-05-19 12:00: Common germline variation and colorectal cancer (Richard Hubner, Royal Marsden Hospital)

2009-05-21 13:00: The Role of Risk Stratification in Treatment Selection for Patients with Prostate Cancer (Carlos Cordon-Cardo, Herbert Irving Comprehensive Cancer Center, Columbia University)

2009-05-21 16:15: A Mystery Solved: Why Lis1 ans NudE are important for dynein mediated nuclear migration (Dr Steven Gross-University of California, Irvine.)

2009-05-26 12:00: Using genetics to personalize melanoma therapy (Keiran Smalley, Moffitt Cancer Center)

2009-05-27 15:00: Characterisation of structural variation in 24 breast cancer genomes using paired-end sequencing on the Illumina Genome Analyser (Phil Stevens, Wellcome Trust Sanger Institute)

2009-06-02 12:00: A model for all genomes: the role of RNA polymerases fixed in factories (Peter Cook, University of Oxford)

2009-06-04 16:15: How transcription factors deal with nucleosomes (Mark Ptashne, Memorial Sloan-Kettering Cancer Centre, New York)

2009-06-09 12:00: Translational imaging studies in ovarian cancer (James Brenton, CRUK Cambridge Research Institute and Evis Sala, Department of Radiology)

2009-06-11 13:00: Breast cancer: origins and evolution (Kornelia Polyak, Dana-Farber Cancer Institute, Harvard Medical School)

2009-06-16 12:00: Is brain cancer a stem cell disease? (Colin Watts, Department of Clinical Neurosciences)

2009-06-17 15:15: Investigation of human mammary stem and progenitor subpopulations from BRCA1 mutation carriers and non-carriers (Elgene Lim, The Walter and Eliza Hall Institute of Medical Research, Victoria, Australia)

2009-06-23 12:00: Germ Cell Tumours (GCTs) of Young People: Clinical and Biological Approaches (James Nicholson and Matthew Murray, Paediatrics, Addenbrooke's Hospital)

2009-06-30 12:00: Genome scans in breast and prostate cancer - what have we learned & where next? (Doug Easton, Strangeways Research Laboratory)

2009-07-02 09:30: Prospective translational research in clinical trials (Helena Earl, Department of Oncology)

2009-07-09 16:15: Genes and Cells that Influence the Lifespan of C. elegans (Cynthia Kenyon, University of California San Francisco)

2009-09-08 12:00: Adoptive T Cell Therapy of Cancer (Cassian Yee, Fred Hutchinson Research Center, Seattle)

2009-09-08 16:15: G protein signaling in photoreceptors (Vadim Arshavsky, Duke University, USA)

2009-09-14 16:15: Biochemical Society Early Career Lecture:  Structure and specificity of deubiquitinases (David Komander, LMB)

2009-09-15 12:00: Clinical Aspects of Proton Radiotherapy (Prof Tony Lomax, Head of Medical Physics, Centre for Proton Radiation Therapy, Paul Scherrer Institute, Switzerland)

2009-09-24 16:15: Neuronal Differentiation and Mechanosensory Transduction in C. elegans. (Marty Chalfie, Columbia University, USA)

2009-09-25 12:00: Cellular quality control of protein aggregates by chaperones (Bernd Bukau, ZMBH, Universität Heidelberg, Germany)

2009-09-29 10:30: Mapping metazoan gene regulatory networks to understand transcription factor function in health and disease (Bart Deplancke,  Institute of Bio-engineering, School of Life Sciences,  Swiss Federal Institute of Technology in Lausanne (EPFL))

2009-09-29 12:00: Molecular Mechanisms of Cellular Senescence in Cancer and Ageing (Fabrizio d'Adda di Fagagna, IFORM-IEO, Milan)

2009-10-13 12:00: "Immunostimulatory antibodies in cancer treatment" (Prof. Peter Johnson, Professor of Medical Oncology, University of Southampton)

2009-10-20 12:00: "Phospholipase and lysophospholipase D signalling in cancer" (Prof. Michael Wakelam, Institute Director, The Babraham Institute)

2009-10-22 13:00: Adult stem cells: from concepts to reality (Connie Eaves, Terry Fox Laboratory, BC Cancer Research Centre, Vancouver)

2009-10-27 12:00: Steroid Hormone Receptors in Prostate Cancer: A Hard Habit to Break? (Dr Gerhardt Attard, The Institute of Cancer Research and the Royal Marsden Hospital)

2009-11-03 12:00: The irreversibility of cell cycle transitions: why the clock never turns back (Frank Uhlmann, CRUK London Research Institute)

2009-11-10 16:15:  Mass Spectrometry and it's Role in Structural Biology (Carol V Robinson)

2009-11-17 12:00: "The Arguments for and against Sentinel Node Biopsy (SNB) in Melanoma" (Prof. J Meirion Thomas, Royal Marsden Hospital & Imperial College, London)

2009-11-18 16:15:  Role of PRG-1 (plasticity related gene-1) in glutamatergic transmission (Dietmar Schmitz, Charité, Berlin)

2009-11-24 12:00: “Intensity modulated radiotherapy for children’s tumours and estimation of the carcinogenic risk” (Dr Michael Williams & Dr Gail Horan, Addenbrooke's Hospital)

2009-11-26 09:30: Cell Signalling (Ermanno Gherardi, MRC Laboratory of Molecular Biology)

2009-11-26 13:00: Lung cancer chemoprevention: the role of eicosanoids (Mark Geraci, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver)

2009-11-27 16:15: On the origin of RNA and peptide synthesis: clues from biology and prebiotic chemistry (John D Sutherland,  Manchester)

2009-12-01 12:00: Cellular senescence: molecular mechanisms and implications for cancer and aging (Peter Adams, Beatson Institute for Cancer Research, Glasgow)

2009-12-03 16:15: New genes involved in deafness from large-scale mouse screens (Karen Steel)

2009-12-15 12:00: The new LAW of microRNA-mediated gene silencing: implications for lung cancer development (Dr Tyson V. Sharp, School of Biomedical Sciences, University of Nottingham)

2010-01-06 13:00: A tumoral stromal cell that mediates immune suppression (Douglas T. Fearon, Wellcome Trust Immunology Unit, Cambridge)

2010-01-12 12:00: PREDICT: A NEW UK PROGNOSTIC MODE THAT PREDICTS SURVIVAL FOLLOWING SURGERY FOR INVASIVE BREAST CANCER (GC Wishart, EM Azzato, PDP Pharoah, DC Greenberg, J Rashbass, O Kearins, G Lawrence, C Caldas C, PM Ravdin) (Prof. Gordon Wishart, Addenbrooke's Hospital)

2010-01-14 16:15: A Ubiquitin-winnowing machine: Is there ubiquitin chain selection upstream to the proteasome? (Michael Glickman, Technion Haifa, Israel)

2010-01-19 12:00: Investigating the interaction of Radiotherapy & Temozolomidefor Glioblastoma (Dr Raj Jena, Addenbrooke's Hospital)

2010-01-21 13:00: Physical limits of cell migration (Katarina Wolf, Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences)

2010-01-21 16:15: TBC (Venki Murthy, Dept. of Molecular and Cellular Biology at Harvard University)

2010-01-26 12:00: HPV vaccines - will they do their job? (Prof. Margaret Stanley, Dept. of Pathology, University of Cambridge)

2010-02-02 12:00: Can we age in utero? Can we kill cancer cells by making them replicate faster? And other ATR stories… (Oscar Fernandez-Capetillo, Spanish National Cancer Research Centre (CNIO))

2010-02-02 16:00: Non-canonical p38 stress signaling in metabolism and inflammation (Romeo Ricci, Institute of Cell Biology, ETH Zurich)

2010-02-09 12:00: High-throughput Cancer Cell line Screens: Linking Drug Response to Molecular Signatures (Dr Ultan McDermott, Cancer Genome Project, Wellcome Trust Sanger Institute)

2010-02-11 09:30: Why computational biology is useful in the cancer world (Simon Tavaré, CRUK Cambridge Research Institute)

2010-02-16 12:00: The prognostic significance of subtypes of breast cancer classified using immunohistochemistry (Dr Paul Pharoah, Strangeways Research Laboratory/Oncology)

2010-02-18 13:00: JNK signalling in stem cells and cancer (Axel Behrens, London Research Institute, Lincoln's Inn Fields Laboratories)

2010-02-23 12:00: CANCELLED (Dr Alison Dunning, Strangeways Research Laboratory & Dept. of Oncology)

2010-03-02 12:00: The Role of the Receptor Tyrosine Kinase Antagonist, Lrig1, in Normal Tissue Homeostasis and Cancer (Kim Jensen, Anne McLaren Laboratory for Regenerative Medicine and Department of Oncology)

2010-03-08 13:00: Developing network models of disease (Jonathan M.J. Derry, Director of Research, Sage Bionetworks, Seattle)

2010-03-09 12:00: "The Fine Scale Mapping of Breast Cancer Loci found via GWAS - searching for the Causative Variants" (Dr Alison Dunning, Strangeways Research Laboratory)

2010-03-16 12:00: Deciphering the Mammary Epithelial Cell Hierarchy (Dr John Stingl, CRUK Cambridge Research Institute)

2010-03-18 16:15: The evolution of long ncRNAs and Prdm9, a special gene (Chris Pointing, University of Oxford)

2010-03-29 11:15: Unfolding pathways of endoplasmic reticulum stress response and apoptosis in Drosophilia (Don Ryoo, New York Univeristy School of Medicine, USA)

2010-03-30 12:00: "Non-Invasive Diagnosis of Brain Cancer" (Prof. John Griffiths, CRUK Cambridge Research Institute)

2010-04-01 11:15: Some like it hot: nucleosomes mediate temperature sensing (Philip Wigge, John Innes Centre, Norwich)

2010-04-02 14:00: Regulation of Alternative Splicing by Histone Modifications (Reini Luco, National Cancer Institute, National Institutes of Health, Bethesda)

2010-04-13 12:00: CANCELLED (Dr James Brenton, CRUK Cambridge Research Institute)

2010-04-20 12:00: The NCAG Report: Delivering a World Class Chemotherapy Service (Prof Roger James, Previously:  • Deputy Medical Director Maidstone and Tunbridge Wells NHS Trust   • Medical Director Kent & Medway Cancer Network)

2010-04-22 09:30: Stem cell fate (Phil Jones, MRC Cancer Cell Unit, Hutchison-MRC Research centre)

2010-04-22 13:00: In vivo quantitative proteomics to study skin cancer progression (Sara Zanivan, Department of Proteomics and Signal Transduction, Max-Planck Institute for Biochemistry)

2010-04-26 16:15: Gene punctuation: multiple roles of transcriptional termination in regulating eukaryotic gene expression (Nick Proudfoot, University of Oxford)

2010-04-27 12:00: “Macromolecular interactions in the control of chromosome instability” (Prof. Ashok Venkitaramann, (Hutchison-MRC Research Centre))

2010-04-29 09:30: Radiotherapy in the management of cancer (Neil Burnet, Department of Oncology and Addenbrooke's Hospital)

2010-04-29 11:00: The protein atlas - a dictionary of 40% of all non-redundant human proteins (Caroline Kampf, Site Director Uppsala, Human Proteome Resource program)

2010-05-04 12:00: Mechanisms regulating neural differentiation (Kate Storey, University of Dundee)

2010-05-06 16:15: Epigenetic reprogramming in transplanted nuclei (John Gurdon, Gurdon Institute, University of Cambridge)

2010-05-10 16:15: The T cells that nature didn't select (Bent Jakobsen, Immunocore Ltd, Abingdon, Oxon)

2010-05-11 12:00: "Cellular Senescence as a Tumour Suppressor Mechanism, Particular Focus will be on the Autophagy/mTOR Pathway" (Dr Masashi Narita, CRUK Cambridge Research Institute)

2010-05-14 10:30: The patterns and temporal dynamics of genomic instability in metastatic pancreatic cancer (Peter Campbell, Wellcome Trust Sanger Institute)

2010-05-17 13:00: Modelling human colon cancer initiation and progression in the mouse (Professor Alan R. Clarke, Joint Head of Research, Cardiff School of Biosciences)

2010-05-18 12:00: "Stem cell identity and mRNA export: unexpected roles of geminin and GANP" (Prof. Ron Laskey, Hutchison/MRC Research Centre)

2010-05-20 09:30: Talk Cancelled (Guillermo de la Cueva Mendez, Hutchison/MRC Research Centre Cancer Cell Unit.)

2010-05-20 16:15: The genomic code for nucleosome positioning (Jon Widom, Department of Biochemistry, Northwestern University, USA)

2010-05-25 12:00: "A New Window of Opportunity in Prostate Cancer" (Dr Danish Mazhar, Addenbrooke's Hospital)

2010-05-27 13:00: Mapping Synthetic Genetic Interaction Networks by High-throughput RNAi (Michael Boutros, Division of Signaling and Functional Genomics, German Cancer Research Center)

2010-06-03 15:00: Regulation of cell cycle progression by CDK-mediated substrate phosphorylation and ubiquitination (Boris Sarcevic, Unit Head, Cell Cycle and Cancer Unit, St Vincent's Institute, Victoria, Australia)

2010-06-10 09:30: New approaches to the clinical management of cervical cancer (Nick Coleman, MRC Cancer Cell Unit, Hutchison-MRC Research Centre)

2010-06-15 12:00: Dynamic Notch signaling in neural progenitor cells (Ryoichiro Kageyama, Kyoto University, Japan)

2010-06-17 11:30: New RNA-Seq protocol for Illumina sequencing (Chris Streck, Illumina)

2010-06-17 13:00: View of the Cancer Epigenome from Biological and Translational Perspectives (Stephen B. Baylin, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore)

2010-06-22 12:00: "Gastro Intestinal Stroma Tumours (GISTS)" (Dr Ramesh Bulusu, Addenbrooke's Hospital)

2010-06-23 09:30: Definiens Image Analysis for Translational Research and Clinical Diagnostics (Martin Baatz, Manfred Voglmeier and Oliver Lehner - Definiens AG, Munich)

2010-06-28 13:00: Translating airway gene expression into a biomarker for lung cancer (Avi Spira, School of Medicine, Boston University)

2010-06-29 12:00: "Breast Radiotherapy - Past, Present and Future" (Dr Charlotte Coles, Addenbrooke's Hospital)

2010-09-07 12:00: Unravelling cancer cell signalling networks and screening for novel drug targets (Daniel Peeper, The Netherlands Cancer Institute)

2010-09-08 11:15: Assembly and function of K11-linked ubiquitin chains (Michael Rape, University of California, Berkeley, USA)

2010-09-13 11:00: Gene Regulatory Network Guidance of Cellular Identity Choice: Stem Cells to T Cell (Ellen Rothenberg California Institute of Technology, USA)

2010-09-13 12:15: Autophagy: molecular machinery and role in diseases (Tamotsu Yoshimori Osaka University, Japan)

2010-09-14 12:00: Interactions of Epidermal Growth Factor Receptor Inhibition with DNA damage in the treatment of gastrointestinal cancer (Prof Daniel Hochhauser, University College London)

2010-09-16 13:00: Transcriptional Lego: Predictable control of gene expression by manipulating promoter building blocks (Eran Segal, Weizmann Institute of Science)

2010-09-21 12:00: Pathway Analysis of Glioblastoma Tissue After Preoperative Treatment with the EGFR Tyrosine Kinase Inhibitor Gefitinib – A Phase “0 Trial” (Dr Monika Hegi, University Hospital (CHUV), Lausanne, Switzerland)

2010-09-21 16:15: Connecting transcription with mRNA processing and chromatin (Steve Buratowski Harvard Medical School, USA)

2010-09-22 14:00: 3rd Generation Sequencing Technology (Ion Torrent)

2010-09-28 12:00: “EGFR Mutation Screening in NSCLC” (Dr David Gonzalez de Castro, The Institute of Cancer Research and Royal Marsden Hospital)

2010-09-29 16:15: Small Molecules and Light as Tools for the Regulation of Biological Proceeses (Alex Deiters, North Carolina State University, USA)

2010-10-07 16:15: Role of intrinsic Flexibility in Protein Regulatory Mechanisms (Richard Kriwacki, St Jude's Children's Research Hospital, USA)

2010-10-12 12:00: "Imaging Tumour Cell Death" (Prof. Kevin Brindle, CRUK Cambridge Research Institute)

2010-10-19 12:00: "Brain Metastases – a cross cutting theme: Review of the Brain Metastasis Service and Future Research Potential" (Dr Sarah Jefferies, Addenbrooke's Hospital)

2010-10-21 13:00: Biological lessons from presurgical studies of breast cancer (Mitch Dowsett, Institute of Cancer Research, Royal Marsden Hospital)

2010-10-25 16:15: Ion channels: Structure, modulation, and unconventional approaches (Dan Minor, University of California, San Francisco, USA)

2010-10-26 12:00: "Chromosome Translocations and Tumour Suppressors in Breast Cancer" (Dr Paul Edwards, Hutchison/MRC Research Centre)

2010-11-05 14:15: Mitosis and Meiosis in live mammalian cells: From genome wide RNAi profiling to homologous chromosome segregation (Jan Ellenberg, EMBL, Heidelberg, Germany)

2010-11-11 13:00: Inflammation, metabolism, ageing and cancer: Dangerous Liaisons (Michael Karin, University of California, San Diego)

2010-11-15 14:00: Nucleocytoplasmic Transport Machinery and Pathways: Cell Cycle Regulation and Stress Response (Naoko Imamoto, Cellular Dynamics Laboratory, RIKEN ASI)

2010-11-15 16:15: Regulation of microRNA biogenesis and function (Javier F Caceres, MRC Human Genetics Unit, Edinburgh)

2010-11-18 09:30: Oncogenes and Tumour Suppressors 1 & 2 (Ashok Venkitaraman & Dave Tuveson; Hutchison/MRC Research Centre & Cambridge Research Institute)

2010-11-18 16:15: Deconstructin oncogenesis and tumour suppression to find the best cancer drug targets (Gerard Evan, Department of Biochemistry, Unversity of Cambridge)

2010-11-22 16:15: Dehydrated but unharmed? – the mass spectrometry of protein complexes (Professor Carol Robinson, Department of Chemistry,  Oxford University)

2010-11-23 12:00: Targeting NG2 Cells in Glioblastoma (Dr Colin Watts, Cambridge Centre for Brain Repair)

2010-11-23 16:15: Femtosecond Membrane-Protein Nanodiffraction using a Hard X-Ray Laser (John Spence, Arizona State University)

2010-11-25 09:30: Tumour suppressors mechanisms and cellular senescence (Masashi Narita, CRUK Cambridge Research Institute)

2010-11-30 12:00: "Susceptibility to Cancer - What's New?" (Prof Doug Easton, Strangeways Research Laboratory)

2010-12-02 14:30: Neuroblastoma- Disordered Developmental Programs Contribute to Tumorigenesis (Prof Carol Thiele, National Cancer Institute, USA)

2010-12-06 16:15: Structural insights into the process of co-translational targeting of membrane proteins and translation initiation in eukaryotes (Nenad Ban)

2010-12-10 14:15: Protein folding homeostasis and prion-like propagation of protein aggregation in neurodegenerative disease (Ron Kopito, Stanford University, CA USA)

2010-12-13 16:15: Structural biology of bacterial secretion systems (Gabriel Waksman)

2010-12-14 12:00: RCC Cinderella comes of age (Prof. Tim Eisen, Dept. of Oncology, University of Cambridge & Addenbrooke's Hospital)

2010-12-21 12:00: “Breast MRI by  the Shutter-Speed Method: Elimination of Unnecessary Breast Biopsies" (Dr Charles S. Springer, Jr., Advanced Imaging Research Centre. Oregon Health & Science University)

2010-12-21 12:00: Breast MRI by the Shutter-Speed Method: Elimination of Unnecessary Breast Biopsies (Charles S. Springer Jr, Oregon Health and Science University, USA)

2011-01-11 16:15: The mechanism of retroviral DNA integration through X-ray structures of its key intermediates (Peter Cherepanov, Faculty of Medicine, Imperial College)

2011-01-20 09:30: Systems approaches to understanding transcriptional regulation (Duncan Odom, CRUK Cambridge Research Institute)

2011-01-20 13:00: Reverse Phenotyping: Towards an integrated (epi)genomic approach to complex phenotypes and common disease. (Stephan Beck, UCL Cancer Institute)

2011-01-25 12:00: "Leukaemia stem cells: how normal stem cell function is subverted in haematological malignancies" (Dr Brian Huntly, Department of Haematology)

2011-01-25 16:15: Interactions of Cancer Stem Cells with their Niches are Essential for Breast Cancer Metastasis (Dr Joerg Huelsken, Swiss Federal Univerity of Technology, Lausanne, Switzerland)

2011-01-27 09:30: Control of DNA Replication (Ron Laskey, MRC Cancer Cell Unit, MRC-Hutchison Research Centre)

2011-01-27 16:15: Crystal structures of bacterial and yeast ribosomes (Marat Yusupov, Illkirch, France)

2011-01-31 16:15: Off-the-shelf models of chromosomal translocations and using antibody fragments as cancer drug surrogates (Terry Rabbitts, Leeds Institute of Molecular Medicine)

2011-02-01 12:00: Application of Systems Biology Approaches to Study Cell Signalling and Transcription (Prof Mike White, University of Liverpool)

2011-02-03 16:15: Genetic approaches to understand and manipulate retinal circuit function (Botond Roska, Friedrich Miescher Institute for Biomedical Research)

2011-02-07 16:15: In vitro and in vivo single molecule studies of chromosome replication and segregation (David Sherratt, University of Oxford)

2011-02-08 16:15: Transcription and R-loops as a source of genome instability (Andrés Aguilera, University of Seville)

2011-02-15 12:00: "Targetting pre-neoplasia in the bronchus" (Dr Robert Rintoul, Papworth Hospital)

2011-02-15 16:15: Pre- and postsynaptic NMDA receptors in neocortical synaptic plasticity (Ole Paulsen, Department of Physiology, University of Cambridge)

2011-02-17 13:00: MAL: linking the actin cytoskeleton to transcriptional regulation (Richard Treisman, Cancer Research UK London Research Institute, Lincoln's Inn Fields)

2011-02-17 16:15: Transport mechanism and membrane interactions of the cation pumps (Poul Nissen, Aarhus University, Denmark)

2011-02-18 11:30: Accuracy of codon reading by transfer RNAs (Måns Ehrenberg)

2011-02-21 13:00: Analysis of Sprouty2 in human prostate carcinogenesis (Hing Leung, Beatson Institute for Cancer Research)

2011-02-22 12:00: Mesothelioma: a disease of our time (Dr David Gilligan, Addenbrooke's Hospital)

2011-03-08 12:00: "FGF-2, S6 Kinase 2 and Chemo-resistance in Lung Cancer" (Prof. Michael Seckl, Imperial College, London and Charing Cross Hospital)

2011-03-15 12:00: "The Cambridge breast cancer program- recent progress" (Dr Carlos Caldas, CRUK Cambridge Research Institute)

2011-03-17 16:15: Non-classical means for regulating small G-proteins (Shehab Ismail, Max Planck Institute Dortmund)

2011-03-21 16:15: Repeat Proteins:Versatile frameworks for understanding and engineering protein structure and function (Lynne Regan, Yale University)

2011-03-25 16:15: The Structural Basis of Ubiquitin Signalling (Cynthia Wolberger, Johns Hopkins University)

2011-03-28 16:15: The Female Side of Fertilization: Crystal Structure of Vertebrate Sperm Receptor ZP3 (Luca Jovine, Karolinska Institute)

2011-03-31 16:15: The Cellular Basis for the Cancer-Related Phenomena of Immune Suppression and Cachexia (Doug Fearon)

2011-04-06 11:30: The Chemical Biology of Large-Scale Transcriptome Analysis (Kevin Weeks, University of North Carolina)

2011-04-07 16:15: Milstein Lecture 2011: How the endoplasmic reticulum gets into shape (Tom Rapoport, Harvard Medical School)

2011-04-12 12:00: "Somatic Genetics of Human Cancer - Moving Towards Large Scale Resequencing of Cancer Genomes" (Dr Andy Futreal, The Wellcome Trust Sanger Institute, Hinxton)

2011-04-12 16:15: A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae (Anne-Claude Gavin, EMBL)

2011-04-14 09:30: Signal transduction and membrane trafficking (Ian Mills, CRUK Cambridge Research Institute)

2011-04-14 16:15: Controlling Recombination (Simon Boulton, CRUK Clare Hall Laboratories)

2011-04-15 16:15: Feldberg Prize Lecture: Biogenesis of iron-sulfur proteins in eukaryotes (Professor Roland Lill, Philipps University Marburg, Germany)

2011-04-26 12:00: CANCELLED (Dr Vincent Gnanapragasam, Hutchison/MRC Research Centre & Addenbrooke's Hospital)

2011-05-03 12:00: CANCELLED (Prof Sibylle Mittnacht, The Institute of Cancer Research)

2011-05-06 16:15: Genome-wide analysis of AID activity and AID-mediated translocations in B lymphocytes (Rafael Casellas, NIH)

2011-05-10 12:00: "Multi-site post-translational modification as a quantitative regulator of transcriptional output during neurogenesis" (Dr Anna Philpott, Department of Oncology, MRC-Hutchison Research Centre)

2011-05-12 16:15: A primer on DNA origami and why molecular biologists might care (Hendrik Dietz, TU Munich)

2011-05-17 12:00: CANCELLED (Prof. Roy Rampling, University of Glasgow and The Beatson Cancer Centre, Glasgow)

2011-05-17 16:15: Delivery Boy to Reporter: Unusual DNA’s journey through a worm-whole (Yamuna Krishnan, National Centre for Biological Sciences Bangalore)

2011-05-19 14:30: Haloplex technology: a genome capture system for next generation sequencing (Olle Ericsson, Halo Genomics)

2011-05-19 16:15: Genetic Architecture of Leukaemia (Mel Greaves, Institute of Cancer Research)

2011-05-24 12:00: “What lessons can we learn from transcriptional evolution in cancer research?” (Dr Duncan Odom, CRUK Cambridge Research Institute)

2011-05-26 09:30: Genomic Imprinting and Cancer (Adele Murrell, CRUK Cancer Research Institute)

2011-05-31 12:00: SOCCAR trial: an update (Dr Joe Maguire, Consultant Clinical Oncologist, Clatterbridge Centre for Oncology)

2011-06-01 11:30: Visualizing vesicle and virus budding by electron microscopy (John Briggs, EMBL)

2011-06-02 17:00: Metabolomic Studies of Cancer Using 13C Tracer Substrates and Model Fitting (Laszlo G Boros, Associate Professor of Paediatrics, UCLA School of Medicine, and Chief Scientist, SiDMAP LLC, Los Angeles, USA)

2011-06-07 12:00: "Developing Medicines for Pancreatic Cancer" (Dr Dave Tuveson, CRUK Cambridge Research Institute)

2011-06-14 12:00: "Advances in Head and Neck Radiotherapy" (Dr Chris Nutting, Royal Marsden Hospital)

2011-06-16 13:00: Changing Cancer Mortality (Richard Peto, Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford)

2011-06-16 16:15: Exploring and exploiting chromosome repair and segregation mechanisms in cancer (Ashok Venkitaraman, MRC Cancer Cell Unit)

2011-06-21 12:00: ‘Viral and host contributions to cervical carcinogenesis’ (Dr Nick Coleman, Department of Pathology & Hutchison/MRC Research Centre)

2011-06-22 14:30:  Autoantibodies against NMDA receptors and other neuronal targets: the widening spectrum of antibody-mediated CNS disorders (Angela Vincent, University of Oxford)

2011-06-27 13:00: Progress towards a biomarker discovery-to-development pipeline in clinical proteomics (Michael Gillette, Broad Institute of MIT and Harvard)

2011-06-28 12:00: The ATM-mediated DNA damage response: moving between the forest and the trees (Dr Yossi Shiloh, Tel Aviv University, Israel)

2011-07-01 16:00: Learnings from kinase inhibitors for cancer therapy (Gideon Bollag (Senior Vice President of Research for Plexxikon Inc., California))

2011-07-07 13:00: Integrated Solutions in Cancer Genomics (Edison Liu, Genome Institute of Singapore)

2011-07-07 16:15: Tuberculosis Treatment Dicta from the Zebrafish (Lalita Ramakrishnan, University of Washington)

2011-07-14 13:00: Modeling non-familial colon cancer susceptibility in mice (David Threadgill, Department of Genetics, North Carolina State University)

2011-07-14 16:15: PDBe - Bringing Structure to Biology (Gerard Kleywegt, EMBL-EBI)

2011-07-25 16:15: Self-assembled DNA-nanostructure tools for molecular biophysics (William Shih, Harvard Medical School)

2011-08-25 12:00: HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 Herceptin in breast cancer (Anthony Kong, Weatherall Institute of Molecular Medicine, University of Oxford)

2011-09-06 12:00: Haploid Genetic Screens in Human Cells (Dr Thijn Brummelkamp, Netherlands Cancer Institute)

2011-09-09 16:00: Genetic dissection of emotion circuits in flies and mice - Francis Crick Lecture 2011 (Dr David Anderson, California Institute of Technology, USA)

2011-09-16 16:15: Molecular and cellular mechanisms for memory allocation in neuronal networks (Alcino Silva, UCLA)

2011-09-20 12:00: DNA repair inhibitors in cancer treatment (Prof Hilary Calvert, UCL Cancer Institute)

2011-09-30 16:15: mRNA-tRNA translocation intermediates by cryo-EM: a look at the free-energy landscape from a single sample. (Joachim Frank, Columbia University)

2011-10-04 11:00: Translational Cancer Genomics Research (Affymetrix)

2011-10-04 12:00: Tumour-stroma Interactions in Breast Cancer (Prof Clare Isacke, Breakthrough Breast Cancer Research Centre, Institute of Cancer Research)

2011-10-04 13:00: So what is the real function of chromatin? (David Bazett-Jones: Senior Scientist, The Hospital for Sick Children, Professor, Department of Biochemistry, University of Toronto)

2011-10-06 16:15: DNA-dependent protein kinase is a DNA sensor for IRF-3-dependent innate immunity (Geoffrey Smith, Department of Pathology Cambridge)

2011-10-11 11:00: Regulation of tumour adaptability in endocrine resistant breast cancer (Leonie Young, Royal College of Surgeons, Dublin)

2011-10-17 16:00: Membrane protein insertion and quality control (Dr Ramanujan Hegde)

2011-10-18 12:00: ‘Genetic predisposition to cancer’ (Prof Bruce Ponder, Cancer Research UK Cambridge Research Institute)

2011-10-20 13:00: Transcriptional Regulation of Cell State (Richard Young, Whitehead Institute for Biomedical Research and M.I.T.)

2011-10-25 10:30: The use of cell lines – promises and pitfalls (Ian Freshney, Cancer Research UK Centre for Oncology and Applied Pharmacology, University of Glasgow)

2011-10-28 16:15: Neuronal plasticity: from synapses to the axon initial segment (Juan Burrone, Kings College London)

2011-10-31 16:15: Structural Studies on the Regulation of Protein Kinases: EGFR and CamK-II (John Kuriyan, HHMI, University of California, Berkeley)

2011-11-01 12:00: Cancer Gene Discovery in the Mouse (Dr David Adams, Wellcome Trust Sanger Institute)

2011-11-07 17:00: Endosomes and the control of the immune response by dendritic cells (Dr Ira Mellman, Genentech, USA)

2011-11-10 09:30: Barrett's oesophagus as a model for early cancer detection/treatment (Rebecca Fitzgerald, Hutchison/MRC Research Centre)

2011-11-10 13:00: Drug resistance and disease progression: lessons from prostate cancer (Charles Sawyers, Memorial Sloan Kettering Cancer Centre)

2011-11-15 16:15: The Evolution of Enzyme Mechanisms and Functional Diversity (Janet Thornton, EMBL-EBI)

2011-11-17 13:00: The intrinsic and extrinsic regulation of stem cells self-renewal (Sean J Morrison, Children’s Research Institute, University of Texas Southwestern Medical Center)

2011-11-21 16:00: Understanding cell shape: reconstitutions of actin polymerisation at the membrane-cytosol interface (Dr Jenny Gallop)

2011-11-21 16:00: Understanding cell shape: reconstitutions of actin polymerisation at the membrane-cytosol interface (Dr Jenny Gallop)

2011-11-24 16:15: Structural and Mechanistic Studies of the Anaphase Promoting Complex (David Barford, Institute of Cancer Research)

2011-12-01 09:30: Cancer Therapeutics (Duncan Jodrell, Cambridge Research Institute and Department of Oncology)

2011-12-01 16:00: Ultrastructural dynamics of proteins involved in endocytic budding (Dr Maribel Geli-Fernandez, Institut de Biologia Molecular de Barcelona)

2011-12-05 10:30: Novel risk biomarkers based on DNA repair for early detection and prevention of lung cancer. (Zvi Livneh, Weizmann Institute of Science)

2011-12-05 16:00: The role of clathrin in mitosis (Dr Steve Royle, University of Liverpool)

2011-12-06 12:00: Integration of Cell Growth and Cell Metabolism by Myc (Prof Martin Eilers, Theodor-Boveri-Institute, University of Würzburg, Germany)

2011-12-08 13:00: *CANCELLED* Wnt signalling, Lgr5 stem cells and cancer (Hans Clevers, Hubrecht Institute)

2011-12-13 12:00: Neo-adjuvant radiochemotherapy in breast cancer (Dr Alain Fourquet, Department of Radiation Oncology, Institut Curie, Paris)

2011-12-15 16:15: Signaling through the ubiquitin system (Wade Harper, Harvard Medical School)

2012-01-09 16:00: Regulation of integrin activity and endosomal traffic (Dr Johanna Ivaska)

2012-01-09 16:00: Regulation of integrin activity and endosomal traffic (Dr Johanna Ivaska)

2012-01-19 13:00: Inflammatory skin disease and Cancer:  Functions of AP-1 (Fos/Jun) in mice and humans (Erwin Wagner, CNIO Madrid)

2012-01-23 16:15: Functions of Dynamin A, Myosin IB and WASH in phagolysosome biogenesis, and the Exocyst in kiss-and-run exocytosis in Dictyostelium (Thierry Soldati, University of Geneva)

2012-01-24 12:00: “Imaging Biomarkers in Cancer” (Prof. Fiona Gilbert, Dept. of Radiology)

2012-02-02 09:30: MRI and MRS in cancer research and cancer treatment (John Griffiths, Cambridge Research Institute)

2012-02-02 15:00: A STAT3‐induced metabolic switch involved in tumour transformation mediates STAT3 addiction (Valeria Poli, University of Turin)

2012-02-02 16:15: New concepts in host-pathogen interactions: lessons from Listeria (Pascale Cossart, Institute Pasteur, Paris)

2012-02-06 16:00: Title to be confirmed (Dr Andrew Peden)

2012-02-06 16:00: Insights into post-Golgi trafficking from a SNARE specific siRNA screen (Dr Andrew Peden, CIMR)

2012-02-07 12:00: Transcriptional control of EMT and malignant tumor progression (Prof Gerhard Christofori, University of Basel, Switzerland)

2012-02-14 12:00: "Radiotherapy toxicity, Radiogenomics and RAPPER" (Dr Gill Barnett, Dept. of Oncology)

2012-02-15 16:15: Crick Lecture 2012: Consequences of Aneuploidy (Angelika Amon, HHMI, MIT)

2012-02-16 09:30: Imaging tumour responses to treatment (Kevin Brindle, Dept. Biochemistry and Cambridge Research Institute)

2012-02-16 13:00: Chromosome Segregation and Genome Stability (David Pellman, Dana-Farber Cancer Institute, Harvard Medical School)

2012-02-21 11:30: Structural and Biochemical Mechanisms of Synchronous Synaptic Transmission (James Rothman, Yale University)

2012-02-21 12:00: "Myeloproliferative neoplasms – JAK/STAT signalling and stem cell subversion" (Prof Tony Green, University of Cambridge Department of Haematology)

2012-02-23 09:30: Functional breast cancer genomics: from basic biology to clinical application (Carlos Caldas, CRI)

2012-02-23 10:00: Cellular senescence as both a dynamic and a static phenotype (Masashi Narita, Cambridge Research Institute)

2012-02-24 09:30: Why 90% of novel anticancer agents are ineffective in clinical trial – and what to do about it (John Hickman, Coordinator, EU Innovative Medicines Initiative PREDECT, Paris)

2012-02-28 12:00: "DICER1 and miRNA processing - a novel paradigm in  cancer predisposition" (Dr Marc Tischkowitz, Dept of Medical Genetics, University of Cambridge)

2012-03-05 16:00: Title to be confirmed (Professor Mikael Simons)

2012-03-05 16:00: Cell polarity in myelinating glia: From membrane flow to diffusion barriers (Professor Mikael Simons, Max Planck Institute for Experimental Medicine, Germany)

2012-03-06 16:15: Disruptions on the Highways of Cell Communication (Dario Alessi, MRC Protein Phosphorylation Unit, University of Dundee)

2012-03-12 16:15: A Chemicogenetic approach to DNA repair implicates TORC2 and actin in survival of DNA breaks (Susan Gasser, Friedrich Miescher Institute for Biomedical Research)

2012-03-13 12:00: "Re Service Reforms in the new Commissioning Landscape" (Hannah Farrar, Director of Strategy and System Management, NHS, London)

2012-03-15 09:30: Clinical lectures on prostate, bladder, renal and testis cancer (David Neal, Cancer Research UK Cambridge Research Institute)

2012-03-15 13:00: Pluripotency, Etc. (Ihor Lemischka, Mount Sinai Medical Centre)

2012-03-20 12:00: "Thalidomide and its analogues ; How molecules selected for anti-TNFa activity affect so many different pathways with direct binding with Cereblon mediating both anti proliferative and Immunomodulatory functions" (Jerome B. Zeldis CEO of Celgene Global Health & Angus Dalgleish, St George's Hospital London)

2012-03-27 11:30: "Exploiting ASS1 deficiency in the treatment of mesothelioma" (Dr Peter Szlosarek, Cancer Research UK Clinician Scientist, Senior Lecturer and Honorary Consultant in Medical Oncology, Barts and The London)

2012-04-03 12:00: Always on guard: p53 dynamics in single living cells (Dr Alexander Loewer, Berlin Institute for Medical Systems Biology, Max Delbrueck Center, Germany)

2012-04-03 16:15: John Kendrew Lecture 2012: Harnessing actin dynamics for endocytic trafficking events (David Drubin, Berkeley)

2012-04-04 13:00: Towards unification of genetic and hierarchy models of tumor heterogeneity (John Dick, University of Toronto)

2012-04-13 16:15: Ubiquitin flips the anaphase switch (David Morgan, UCSF)

2012-04-19 14:00: Molecular mechanisms of complement activation and regulation (Piet Gros, Utrecht University)

2012-04-19 16:15: Gene expression programs controlling ER-negative breast cancer phenotype (Alex Swarbrick, Garvan Institute, Australia)

2012-04-20 15:00: The ETS transcription factor ELF5 and breast cancer phenotype (Chris Ormandy, Garvan Institute, Australia)

2012-04-23 16:00: Microtubule depolymerisation as a cellular machine. (Professor Dick McIntosh, University of Colorado at Boulder, USA)

2012-04-24 12:00: CANCELLED (Prof Richard Sullivan, Professor, Kings College London, Director, Centre for Global OncoPolicy & Health Kings Health Partners)

2012-04-26 16:15: How end binding proteins recognise growing microtubule ends: from molecular structure to network functioning (Thomas Surrey, Cancer Research UK, London Research Institute)

2012-04-30 16:15: Local Translation at the Synapse (Erin Schuman, Max Planck Institute)

2012-05-03 15:00: Massively multi-parameter single cell data by Mass Cytometry:  the technology of its acquisition and networks for its interpretation (Scott Tanner, University of Toronto and DVS Sciences)

2012-05-03 17:00: ALK Hunting in Colorado - new drugs for lung cancer's new diseases (Dr Ross Camidge,  University of Colorado Hospital (UCH) and the University of Colorado Cancer Center,)

2012-05-08 12:00: Investigating key effectors downstream of APC (adenomatous polyposis coli)  deletion in vivo (Prof Owen Sansom, Beatson Institute, Glasgow)

2012-05-10 16:15: Monitoring protein synthesis one codon at a time through ribosome profiling (Jonathan Weissman, Howard Hughes Medical Institute, UCSF)

2012-05-14 16:00: Actin polymerization by the WASH complex promotes lateral compartmentalization of endosomes and membrane fission (Dr Alexis Gautreau, CNRS)

2012-05-15 12:00: "Strategies to enhance effectiveness of Radiotherapy in Pancreatic Cancer" (Dr Thomas Brunner, Gray Institute for Radiation Oncology and Biology, Oxford)

2012-05-17 13:00: Common and rare variants in the sequence of the human genome that affect the risk of cancers  and other diseases of man (Kari Stefansson, deCODE Genetics, Iceland)

2012-05-17 16:15: Milstein Lecture 2012: How do we sense microbes?  From LPS, TNF, and the TLRs. (Bruce Beutler, UT Southwestern Medical Centre)

2012-05-21 16:15: The structural and mechanistic basis for Rab cycling and targeting (Roger Goody, MPI Dortmund)

2012-05-29 12:00: Pancreatic cancer: Genetic models to develop novel diagnostic and therapeutic strategies (Dr Dieter Saur, The Technical University of Munich)

2012-06-11 16:00: Epigenetic Enginnering of Human Kinetochores (Professor William Earnshaw)

2012-06-11 16:00: Epigenetic Enginnering of Human Kinetochores (Professor Bill Earnshaw, University of Edinburgh)

2012-06-12 12:00: Cancer-related inflammation (Dr Thorsten Hagemann, Barts Cancer Institute, Queen Mary University of London)

2012-06-12 16:15: Shedding light on Ubiquitin Modification in Cancer. (Vishva Dixit, Genentech)

2012-06-13 13:00: The dynamic organization of the Golgi apparatus and its role in integrin regulation and tumor metastasis (Dr Frederic Bard, Institute of Molecular and Cell Biology, A*Star, Singapore)

2012-06-21 13:00: Cellular Conversations that Control Cell Fate (Thea Tlsty, University of California, San Francisco)

2012-06-21 16:00: Understanding Response & Resistance Mechanisms to Targeted Therapy (Dr Keith Flaherty, Director of Developmental Therapeutics at Massachusetts General Hospital)

2012-06-22 16:15: Mechanisms for the Selective Degradation of Ubiquitinated Proteins by the 26S Proteasome (Fred Goldberg, Harvard Medical School)

2012-07-05 16:00: The Unfolded Protein Response in Health and Disease (Professor Peter Walter, University of California San Francisco)

2012-07-11 16:15: Normal and neoplastic stem cells (Irving Weissman, Stanford School of Medicine)

2012-07-19 13:00: The role of telomeres and telomerase in stem cell biology, cancer and ageing (Maria Blasco, CNIO, Madrid)

2012-07-19 16:00: How mitotic spindles adapt to the presence/absence of centrosomes (Hélder Maiato, Universidade do Porto, Portugal)

2012-08-14 12:00: 'Circulating Tumour Cells: Biomarker Utility and Insights to Metastasis' (Professor Caroline Dive, Clinical and Experimental Pharmacology Group, Paterson Institute for Cancer Research, Manchester)

2012-09-11 13:00: Lgr5 stem cells in self-renewal and cancer (Hans Clevers, Hubrecht Institute, The Netherlands)

2012-09-11 13:00: Lgr5 Stem Cells in self-renewal and cancer (Hans Clevers, Hubrecht Institute)

2012-09-12 13:00: Niche, signaling, and epigenetic regulation of stem cells (Linheng Li, Stowers Institute for Medical Research)

2012-09-13 11:45: Functional heterogeneity in intestinal stem cells and cancer (Doug Winton, Cancer Research UK Cambridge Research Institute)

2012-09-13 16:15: Max Perutz Lecture 2012: Defective DNA strand break repair, genome instability and cancer (Steve West, CRUK LRI - Clare Hall)

2012-09-17 11:30: New insights into the role of the chromatin associated factor ATRX (Doug Higgs, MRC Molecular Haematology Unit, Oxford)

2012-09-20 13:00: Challenges in Building a Genomic Prescribing System (Mark J. Ratain, Director, Center for Personalized Therapeutics, University of Chicago)

2012-10-03 13:00: The Ras pathway in cancer therapy (Frank McCormick, UCSF Helen Diller Family Comprehensive Cancer Center)

2012-10-08 16:00: Actin dynamics and trafficking in Cancer Cell Invasion (Professor Laura Machesky, University of Glasgow  and The Beatson Institute for Cancer Research)

2012-11-05 16:00: Cell shape through the cell cycle (Dr Buzz Baum, UCL/LMCB )

2012-11-06 12:00: Signalling Networks in Cell Proliferation and Fate Control (Professor Sibylle Mittnacht, UCL Cancer Institute)

2012-11-06 16:00: A genomic Odyssey of predicting drug response: is Ulysses home yet? (Dr Federico Innocenti, UNC Institute for Pharmacogenomics and Individualized Therapy)

2012-11-07 10:30: A systems view of the cancer cell: from missing genetic variability to combination therapy (Andrea Califano, Columbia University)

2012-11-13 12:00: "Towards personalized medicine in Breast Cancer" (Prof. Dr. Sabine C. Linn, medical oncologist Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands)

2012-11-15 13:00: PLEASE NOTE THAT THIS TALK HAS BEEN CANCELLED (Danny Reinberg)

2012-11-20 12:00: Mechanisms of Estrogen Receptor Transcription in Breast Cancer (Dr Jason Carroll, CRUK Cambridge Research Institute)

2012-11-27 12:00: Cellular responses to DNA damage:  translating molecular insights towards new cancer therapies (Prof Steve Jackson, Head of Cancer Research UK Laboratories The Gurdon Institute, Cambridge)

2012-11-29 09:30: **Talk postponed** Introduction to statistics (Sarah Vowler, CRI)

2012-12-03 16:00: PREDicting the function of the unknome (Dr Tim Levine, UCL, Institute of Ophthalmology)

2012-12-03 16:15: Assembly and Dynamics of Uber Complex RNPs (Melissa Moore, University of Massachusetts Medical School)

2012-12-04 12:00: Localisation-based feedback controls during mitosis and the maintenance of chromosomal stability (Dr Adrian Saurin, University Medical Center Utrecht, The Netherlands)

2012-12-11 10:00: Molecular pathology: building the backbone of translational research and personalised medicine (Manuel Salto-Tellez, Queens's University Belfast)

2012-12-13 09:30: Microtubules: boring polymers or the Achilles heel of cancer? (Fanni Gergely, CRUK Cambridge Research Institute)

2013-01-14 16:00: Actin as a regulator of protein function (Dr Richard Treisman, London Research Institute, CRUK)

2013-01-16 11:00: Fundamentals and Applications of Mass Cytometry, using CyTOF (Jane Limer, DVS Sciences)

2013-01-17 09:30: Estrogen receptor and its role in transcription and breast cancer (Jason Carroll, CRI)

2013-01-24 09:30: Stem cells and cancer (John Stingl, Cambridge Research Institute)

2013-01-31 09:30: Proteinases and Cancer (Gill Murphy, CRUK Cambridge Research Institute)

2013-02-05 12:00: Telomeres and the challenges to chromosome integrity (Dr Julie Cooper, London Research Institute)

2013-02-19 12:00: Challenges in Implementing Personalized Cancer Medicine: the IGR experience (Professor Alexander Eggermont, Director General, Institut de Cancérologie Gustave Roussy, France)

2013-02-21 13:00: Molecular dissection and targeting of epigenetic machinery in AML stem cells (Eric So, Department of Haematological Medicine, King's College London)

2013-02-26 16:00: Expansion and spread of oncogenic K-ras mutant stem cells throughout the intestinal epithelium (Hugo Snippert (Molecular Cancer Research, University Medical Center, Utrecht))

2013-03-04 16:00: Signals from the Lysosome  (Dr Andrea Ballabio, Telethon Institute of Genetics and Medicine)

2013-03-07 09:45: Epigenetic cancer conspirators: DNA methylation, non-coding RNA and chromatin loops (Adele Murrell, CRUK Cambridge Institute)

2013-03-12 12:00: CANCELLED  (Dr Fiona Blackhall, Manchester University, Manchester Cancer Research Centre Lung Group Lead)

2013-03-13 12:30: New tools for NGS libraries: Long-Span, Mate-Pair Scaffolding and Methods for Faster Library Creation (David Mead, Founder and Chief Executive Officer of Lucigen )

2013-03-21 09:30: Computational biology (Florian Markowetz, Cancer Research UK Cambridge Research Institute)

2013-03-27 12:00: The mammalian circadian timing system: how the brain communicates with the periphery (Ueli Schibler, University of Geneva)

2013-03-28 13:00: Impact of cancer- and stroma-cell-derived lysosomal proteases on cancer invasion and metastasis (Thomas Reinheckel, University of Freiburg)

2013-04-09 15:00: The genetics of individuals: why would a mutation kill me, but not you? (Ben Lehner, CRG Barcelona)

2013-04-10 11:00: Standardising tumour tissue dissociation to increase the reliability and  reproducibility of downstream analysis (Dawn Farrar, Miltenyi Biotec)

2013-04-15 16:00: Regulating centrosome size during asymmetric stem cell divisions  (Dr Jordan Raff, Sir William Dunn School of Pathology, University of Oxford)

2013-04-16 16:15: Machinery for making coated vesicles (Margaret Scott Robinson, CIMR)

2013-04-18 13:00: The impact of cohesin on the regulation of gene expression and the organization of chromatin (Matthias Merkenschlager, Lymphocyte Development Group, MRC Clinical Sciences Centre, Imperial College London)

2013-04-23 12:00: “The identification of patients who benefit from targeted therapy in renal cancer” (Professor Thomas Powles, Barts Cancer Institute, Queen Mary University of London)

2013-04-30 14:30: Max Perutz Lecture: Five ways that viruses use to enter the animal cell  (Professor Ari Helenius, ETH Zurich, Switzerland)

2013-05-02 16:15: Selective autophagy: when being picky pays of (Ana-Maria Cuervo, Albert Einstein College of Medicine )

2013-05-07 12:00: Macrophages Into Tumor Hypoxic Areas: Should I Stay Or Should I Go? (Dr Massimiliano Mazzone, VIB Vesalius Research Center, Belgium)

2013-05-13 16:00: Cellular functions of the ESCRT Machinery  (Dr Jeremy Carlton, King's College London)

2013-05-13 16:15: Cytoskeletal Control of Leukocyte Chemotaxis (Michael Sixt, IST Austria)

2013-05-14 12:00: ‘CLL – from chemotherapy to targeted kinase inhibition’ (Dr George Follows, Consultant Haematologist, Addenbrooke's )

2013-05-16 10:30: SMARTer cDNA Synthesis for Illumina Sequencing and iDimerize Inducible Dimerization Systems (Syed Abedi, Takara-Clontech)

2013-05-28 12:00: "Renal Cancer and Oxygen Sensing" (Prof Patrick Maxwell, Regius Professor of Physic, University of Cambridge)

2013-06-03 16:00: Regulation of membrane dynamics by phosphatidylinositol 3-phosphate (Profesor Harald Stenmark, Oslo University Hospital, Norwegian Radium Hospital)

2013-06-04 12:00: Control of cytokinesis and the dark side of actomyosin forces (Dr Mark Petronczki, London Research Institute)

2013-06-05 12:00: Direct Selection for Antibodies that Control Cell Fates from Intracellular Combinatorial Antibody Libraries   (Professor Richard Lerner, The Scripps Research Institute, USA)

2013-06-11 12:00: Economics of Cancer Medicines (Professor Richard Sullivan, Guy's Hospital, London)

2013-06-11 17:00: Intrinsic biophysical diversity and connectivity of neuronal circuits (Troy Margrie, NIMR)

2013-06-20 13:00: Duplicating the Human genome: The Origin Recognition Complex et al (Bruce Stillman, FAA, FRS - Cold Spring Harbour Laboratory, New York)

2013-06-25 12:00: "Image guidance – benefits and risks" (Professor Marcel van Herk, Imaging Physicist, Project Leader, The Netherlands Cancer Institute)

2013-06-27 16:15:   The impact of systemic inflammation on the brain in health and disease (Hugh Perry, University of Southampton)

2013-07-02 13:00: Genetic modifiers and microenvironmental control of tumor invasiveness (Prof Douglas Hanahan, EPFL, Switzerland )

2013-07-08 16:00: The organelles and traffic machinery of the late endocytic pathway (Professor Paul Luzio, Cambridge Institute for Medical Research )

2013-07-16 12:00: Risk and uncertainty in radiotherapy.  Why I am the weakest link? (Dr Tom Roques, Lead of Head and Neck Cancer Multidisciplinary Team, Norfolk and Norwich Hospital)

2013-07-18 13:00: HER2 and EGFR: Signalling mechanisms and next generation cancer therapies (Yosef Yarden, Weizmann Institute of Science, Israel)

2013-07-24 16:15: Biological insights from cryo-EM studies of complex macromolecular assemblies in transcription initiation and microtubule dynamics (Eva Nogales, HHMI University of California Berkely)

2013-08-09 16:15: Watching Individual Proteins Working on Single Molecules of DNA: from Biophysics to Cancer (Steve Kowalczykowski, University of California)

2013-09-03 12:00: Insights  for the role of  tumour-related inflammation and stem cells in Drosophila (Dr Marcos Vidal, Beatson Institute, Glasgow )

2013-09-04 11:00: The Evolutionary 'Design' of Proteins (Rama Ranganathan, UT Southwestern Medical Centre)

2013-09-05 16:15: Long-distance organelle transport in the neuron: mechanisms of motor engagement and motor coordination (Erika Holzbaur, University of Pennyslvania)

2013-09-10 12:00: Advances in non-surgical treatment for cervix cancer (Dr Li Tee Tan, Addenbrooke's )

2013-09-19 13:00: Inflammation and Cancer: Reprogramming the immune microenvironment as an anti-cancer therapeutic strategy (Lisa M. Coussens. Department of Cell & Developmental Biology, Knight Cancer Institute, Oregon Health & Sciences University)

2013-09-24 12:00: CANCELLED  (Professor Charles Swanton, CRUK & UCL Trials Centre, UCL)

2013-09-24 16:15: Innate Immune Sensing and Signaling of Cytosolic DNA and RNA (Zhijan 'James' Chen, University of Texas Southwestern Medical Center)

2013-09-26 16:15: Milstein Lecture 2013:  Sorting out protein traffic: Ubiquitin-mediated endocytosis and a membrane protien’s final ESCRT (Scott Emr, Cornell University)

2013-10-01 12:00: Target-Based Approach in Early-Phase Clinical Trials in Cancer (Filip Janku, Investigational Cancer Therapeutics, (Phase I Clinical Trials Program), The University of Texas MD Anderson Cancer Center, Houston)

2013-10-03 16:15: Conformational Conversion  in Amyloid Assembly (Sheena Radford, University of Leeds)

2013-10-04 13:00: Tumor hypoxia: developing prognostic biomarkers to predict therapeutic outcome (Ralph P. Mason, The University of Texas Southwestern Medical Center)

2013-10-07 16:00: Stopping and starting of cell migrations - the role of Ephs and Ephrins during cancer invasion and wound healing (Professor Kate Nobes, University of Bristol )

2013-10-08 12:00: Spotlight on Cambridge Clinical Trials; Presentations from the American Society of Oncology (ASCO) Annual Meeting 2013 (Prof Tim Eisen, Dr Hugo Ford, Dr Pippa Corrie & Dr Kate Fife)

2013-10-10 16:15: Can structural studies of intact viruses really be useful in the search for better vaccines and antivirals? (David Stuart, University of Oxford)

2013-10-15 13:00: Chromatin and its Impact on Gene Expression and Cellular Memory (Danny Reinberg, Howard Hughes Medical Institute, NYU School of Medicine)

2013-10-17 09:30: Development (Anna Philpott, Department of Oncology)

2013-10-29 12:00: CANCELLED -   Scottish Collaboration On Translational Research into Renal Cell Cancer, developing a systems medicine approach to personalised treatment (Mr Grant Stewart, Department of Urology and Edinburgh Urological Cancer Group,Western General Hospital. Edinburgh)

2013-10-31 16:15: Embracing Complexity: A Drosophila Approach To Cancer Therapeutics (Ross Cagan, Mt. Sinai School of Medicine)

2013-11-01 16:15: John Kendrew Lecture 2013:  Noncoding RNAs: with a viral twist (Joan Steitz, Yale University)

2013-11-04 16:00: The p53 pathway: 21 years of  the "guardian of the genome" (Prof Sir David Lane, Chief Scientist, A*STAR, Singapore)

2013-11-07 17:00: Brain Power: Where does it come from and how is it used? (Professor David Attwell, University College London)

2013-11-14 09:30: Introduction to cancer in Cambridge (BP) followed by Cell cycle and checkpoints (AP) (Bruce Ponder and Anna Philpott, Department of Oncology)

2013-11-18 16:00: Molecular strategies for regulating microtubule dynamics (Dr Carolyn Moores, Birkbeck College, London )

2013-11-21 09:30: Stem cells and cancer (Phil Jones, MRC Cancer Unit)

2013-11-25 16:00: Mannose 6-phosphate-dependent and -independent transport of lysosomal enzymes’ (Professor Thomas Braulke, University of Hamburg)

2013-11-26 12:00: "The Cambridge Breast Cancer Programme" (Prof Carlos Caldas, CRUK Cambridge Research Institute)

2013-11-28 13:00: Hallmarks of Cancer: Applications to Cancer Medicine? (Douglas Hanahan, Swiss Institute for Experimental Cancer Research)

2013-12-03 12:00: The autophagy signaling network in the coordination of a cell's response (Prof Francesco Cecconi, University of Tor Vergata, Italy )

2013-12-05 09:30: Tumour metabolism (Christian Frezza, MRC Cancer Unit)

2013-12-09 13:00: Comprehensive transcriptome and epigenome sequencing of hypoxic breast cancer reveals non-coding RNAs associated with clinicopathological features (Ioannis (Jiannis) Ragoussis, McGill University, Canada and Genome Quebec Innovation Centre)

2013-12-12 09:30: Metastasis (Gill Murphy, Cancer Research UK Cambridge Institute)

2013-12-12 13:00: Harnessing Genetic Dependencies in Cancer Therapy (Alan Ashworth, The Institute of Cancer Research, London)

2013-12-12 16:15: GPCRs: From thermostabilisation to X-ray structures and Drug discovery (Fiona Marshall, Heptares Therapeutics)

2013-12-13 13:00: Detecting low-concentration compounds with water sensitivity and spectroscopic specificity using CEST-MRI (Peter van Zijl, Johns Hopkins University and Kennedy Krieger Institute)

2013-12-17 12:00: CANCELLED  (Prof Josep Tabernero, Head, Medical Oncology Department, Vall d' Hebron University Hospital, Barcelona, Spain)

2014-01-07 12:00: Chasing metabolic alterations in cancer (Dr Arkaitz Carracedo, CIC bioGUNE,  (Center for Cooperative Research in Biosciences), Derio, Spain)

2014-01-09 14:00: Systematic cell biology - Moving beyond text-book schemes (Maya Schuldiner, The Weizmann Insitute of Science)

2014-01-14 12:00: Personalized medicine initiative at Gustave Roussy ( Professor Jean-Charles SORIA - Chef de Service, Professor of Medicine and Medical Oncology, Paris University XI and cancer specialist at Institut Gustave, Roussy.)

2014-01-16 13:00: NextGen Research: Enabling distributed teams of experts and the engaged public to solve complex biomedical problems (Stephen Friend, Sage Bionetworks, Seattle)

2014-01-20 16:00: Sphingolipid biosynthesis: dammed if you do, dammed if you don't (Professor Joost Holthuis, Osnabruck University, Germany)

2014-01-23 16:15: Feldberg Prize Lecture: The mitochondrial machinery for transport and assembly of proteins (Klaus Pfanner, University of Freiburg)

2014-02-03 16:00: Spatiotemporal control of endocytosis and endosomal membrane traffic (Professor Volker Haucke, Leibniz Institute for Molecular Pharmacology, Germany)

2014-02-04 12:00: Translating Tumour Metabolism into New Diagnostics and Novel Anti-Cancer Therapeutics (Professor Michael Lisanti, Director of the Breakthrough Breast Cancer Research Unit, University of Manchester)

2014-02-06 09:30: Circulating DNA and diagnostics (Nitzan Rosenfeld, Cancer Research UK Cambridge Institute)

2014-02-10 14:00: Lighting up RNA Interactions in Living Cells (David Tollervey, WTCCB, University of Edinburgh)

2014-02-11 12:00: “What can we do to accelerate the discovery of new medicines for patients?” (Professor Chas Bountra, Head of Structural Genomics Consortium, University of Oxford, Nuffield Dept of Clinical Medicine )

2014-02-12 09:30: Transcriptional regulation and techniques (Duncan Odom, Cancer Research UK Cambridge Institute)

2014-02-24 16:00: How cells ensure chromosome segregation occurs before cytokinesis (Professor Francis Barr, University of Oxford )

2014-02-26 16:15: Type VI Secretion System: structure, function and dynamics of a multicomponent nanomachine that is evolutionarily related to a contractile phage tail (Marek Basler, University of Basel)

2014-02-27 09:30: Computational biology (Florian Markowetz, Cancer Research UK Cambridge Institute)

2014-03-04 12:00: Cell death and autophagy in response to inhibition of glycolysis (Dr Cristina Muñoz Pinedo, IDIBELL, Barcelona, Spain)

2014-03-06 09:30: Solid vs. non-solid tumours (Brian Huntly, Department of Haematology)

2014-03-10 16:00: Organelle size, shape and function: Weibel-Palade bodies of endothelial cells (Professor Dan Cutler, MRC LMCB )

2014-03-13 09:30: Genomic technologies (Jason Carroll, Cancer Research UK Cambridge Institute)

2014-03-19 13:00: Targeted Cancer Therapy: Accomplishments and Challenges (John Mendelsohn, MD Anderson Cancer Center Sheikh Khalifa Bin Zayed Al Nahyan Institute for Personalized Cancer Therapy)

2014-03-19 15:00: **CANCELLED** The role of EGFR family receptor signaling-induced NF-kB activation in human breast cancer (Debajit Biswas, Dana-Farber Cancer Institute and Harvard Medical School)

2014-03-20 09:30: In vivo models (Suzanne Turner, Department of Pathology)

2014-03-20 13:00: Clinical Systems Medicine in Acute Myeloid Leukemia and Beyond (Olli Kallioniemi, Institute for Molecular Medicine Finland)

2014-03-24 15:00: microRNAs, circular RNAs, and micropeptides (Professor Nikolaus Rajewsky, Max Delbrück Center for Molecular Medicine, Berlin)

2014-03-25 16:15: John Kendrew Lecture 2014: Birth and Future of Multi-Scale Modeling of Macromolecules  (Michael Levitt, Standford Unversity)

2014-03-26 13:00: Policing secretion: how cells regulate ER export to enforce quality control  (Professor Liz Miller, Columbia University )

2014-03-27 16:15: Building proteins de novo: better, faster, fitter (Dek Woolfson, University of Bristol)

2014-04-01 12:00: “Personalized Medicine in Oncology: The Dutch experience” (Professor Jaap Verweij, Erasmus MC Cancer Institute, Weytemaweg 80, 3105 CN Rotterdam, The Netherlands)

2014-04-03 09:30: **Postponed to 19 June** Epidemiology (Paul Pharoah, Department of Public Health and Primary Care)

2014-04-04 13:00: Imaging the contractile engine under the hood of cells (Dr Jennifer Lippincott-Schwartz, NICHD-NIH, Bethesda)

2014-04-08 12:00: Targeting bioenergetics in hypoxic and rapidly growing tumours (Dr Jacques Pouysseggur, Institute of Research on Cancer and Ageing (IRCAN), Nice, France)

2014-04-09 11:00: Centrosome changes in cancer – causes and consequences (Monica Bettencourt Dias, Instituto Gulbenkian de Ciência)

2014-04-10 09:30: **Postponed to 22 May** Drug discovery (Grahame McKenzie, MRC Cancer Unit)

2014-04-10 11:00: What can NMR tell us about how a virus enters its host cell? (Ad Bax, NIH)

2014-04-11 15:00: Francis Crick Lecture 2014: Prions Causing Neurodegeneration: A Unifying Etiology and the Quest for Therapeutics (Stanley Prusiner, University of California San Francisco )

2014-04-24 16:15: Structural basis of protein PARylation-dependent ubiquitination (Rachel Klevit, University of Washington)

2014-04-28 16:00: Systems Cell Biology of Poxvirus Infection (Dr Jason Mercer, ETH Zürich / MRC LMCB )

2014-05-01 09:30: Signal transduction  (Ian Mills, Centre for Molecular Medicine Norway)

2014-05-06 12:00: Spatio-temporal control of RhoGTPases and the cytoskeleton in invading cancer cells by integrins and endocytic trafficking (Dr Patrick Caswell, Wellcome Trust Centre for Cell-Matrix Research, University of Manchester)

2014-05-06 13:00: TALK CANCELLED (Joan S Brugge, Harvard Medical School, Cambridge)

2014-05-08 09:30: Therapeutics and clinical trials (Duncan Jodrell, Cancer Research UK Cambridge Institute)

2014-05-13 12:00: "From trials evaluating drugs to trials evaluating treatment algorithms – Focus on the SHIVA trial" (Dr Christophe Le Tourneau, Medical Oncologist, Head of the Phase I Program at the Institut Curie, Paris, France,)

2014-05-14 16:15: Engineering strategies for tuning cell surface receptor signalling (K. Christopher Garcia, Stanford University School of Medicine )

2014-05-19 16:00: Axonal signalling endosomes: trafficking, sorting and disease2 (Dr. Gipi Schiavo University College London)

2014-05-20 12:00: Personalised Cancer Medicine. How do we get there? (Dr Helena Earl, Dept. of Oncology, University of Cambridge)

2014-05-22 09:30: Drug discovery (Grahame McKenzie, MRC Cancer Unit)

2014-05-29 09:30: Metabolism, oxygen and cancer (John Griffiths, Cancer Research UK Cambridge Institute)

2014-06-03 12:00: Undermining Myc: Mitochondria Hold the Key (Dr Daniel Murphy, Institute of Cancer Sciences, University of Glasgow)

2014-06-05 09:30: Radiotherapy (Neil Burnet, Department of Oncology)

2014-06-10 12:00: Breast Imaging research in Cambridge (Professor Fiona Gilbert, Head of Department of Radiology, Cambridge)

2014-06-12 09:30: MRI and MRS in cancer research and treatment (John Griffiths, Cancer Research UK Cambridge Institute)

2014-06-16 16:00: How does the T-cell antigen receptor count to ten? (Dr John James, MRC, LMB Cambridge )

2014-06-19 09:30: Epidemiology (Paul Pharoah, Department of Public Health and Primary Care)

2014-06-24 12:00: Precision Cancer Prevention: Trying to use Genomics to Save Lives (John Hopper, Professor & Director (Research), Centre for Molecular, Environmental, Genetic and Analytic (MEGA) Epidemiology, University of Melbourne, Australia)

2014-06-24 12:30: Relaxation Workshop  (Rosemary Parkinson)

2014-06-26 09:30: Epigenetics and microRNA (Eric Miska, Wellcome Trust/Cancer Research UK Gurdon Institute)

2014-06-26 13:00: *New speaker - replaces previously advertised seminar* (Ravid Straussman, Department of Molecular Cell Biology, Weizmann Institute of Science, Israel)

2014-06-26 16:15: Exploring the final events in eukaryotic cell division (Juan Martin-Serrano, Kings College London)

2014-06-27 13:45: Noninvasive cancer genomics (Nitzan Rosenfeld, Cancer Research UK Cambridge Institute)

2014-06-27 16:15: The function and execution of RTEL1 activities at vertebrate telomeres (Dr Simon Boulton, DNA damage Response Laboratory, London Research Institute)

2014-06-30 16:15: Milstein Lecture 2014: Unfolded Protein Response in Health and Disease (Peter Walter, University of California, San Francisco )

2014-07-10 13:00: Whole-exome sequencing identifies recurrent functional mutations in melanoma  (Yardena Samuels, The Weizmann Institute of Science, Israel)

2014-07-15 11:45: Extrinsic regulation of haematopoietic stem cell self (Sean J. Morrison Investigator, Howard Hughes Medical Institute)

2014-07-22 12:00: 'Scottish Collaboration On Translational Research into Renal Cell Cancer (SCOTRRCC): a springboard for renal cancer biomarker development’.  (Mr Grant Stewart, Clinical Senior Lecturer and Honorary Consultant in Urological Surgery, University of Edinburgh )

2014-07-22 16:15: The Consequences of Whole Genome Duplications (Prof David Pellman, Professor of Cell Biology, Harvard Medical School)

2014-07-28 14:45: Cellular hierarchies in normal and malignant epithelial tissue (John Stingl, Cancer Research UK Cambridge Institute)

2014-09-05 16:15: From static structures to molecular movies: pushing the boundaries of X-ray Crystallography (Wei Yang, NIH, Bethesda, USA)

2014-09-08 14:15: Molecular Architecture and Function of the Exocyst Complex in Vesicle Trafficking (Associate Professor Mary Munson, University of Massachusetts)

2014-09-09 12:00: “Paradigm changes produced by targeted agents in Phase I trials in Oncology. Case studies of a TFbeta inhibitor and a Sonic Hedgehog inhibitor” (Dr Jordi Rodon, Head of Research Unit for Molecular Therapy of Cancer Oncology Department. Vall D’Hebron University Hospital, Barcelona, Spain)

2014-09-18 13:00: The role of macrophages in tumour progression and metastasis (Jeffrey Pollard, University of Edinburgh and Albert Einstein College of Medicine, New York)

2014-09-18 16:15: Feedback control of cell division (Andrea Musacchio, Director, Department of Mechanistic Cell Biology, Max-Planck Institute of Molecular Physiology )

2014-09-19 16:15: Crick Lecture 2014: How Aneuploidy Drives Cancer (Stephen Elledge, Gregor Mendel Professor of Genetics, Department of Genetics, Harvard Medical School)

2014-10-07 12:00: The role of stem cells in the pathogenesis of hepato-biliary cancers (Professor Nisar Malek, University of Tubingen, Germany)

2014-10-07 12:00: “CDD’s new Research Strategy” (Dr Nigel Blackburn, Director of Centre for Drug Development, Cancer Research UK)

2014-10-08 16:00: Title 'TBA' (Dr. Leo James MRC/LMB)

2014-10-14 12:00: CANCELLED -      Lung cancer, biomarkers and unanswered questions - a clinical translational perspective (Dr Fiona Blackhall, Consultant Medical Oncologist, The Christie Hospital, Manchester                    )

2014-10-16 09:30: Tumour natural history, structure and nomenclature (lecture/demonstration) (Paul Edwards,  Department of Pathology)

2014-10-16 13:00: The role of dsRNA in cellular response to genetic change  (Andrew Fire, Stanford University)

2014-10-21 12:00: "The role of epigenetic regulators and their therapeutic targeting in Acute Myeloid Leukaemia and haematological malignancies” (Dr Brian Huntly, Department of Haematology, Cambridge University)

2014-10-30 09:30: Overview of cancer theoretical framework (Paul Edwards,  Department of Pathology)

2014-11-06 16:15: Genome stability and instability during repair of a broken chromosome (Jim Haber, Director, Rosenstiel Basic Medical Sciences Research Center)

2014-11-10 16:15: The amazing hepatocyte: master of disguise and adaptation (Dr Markus Grompe)

2014-11-11 12:00: “Stratified Medicine in Cancer Therapy - a practical guide” (Professor Gary Middleton, Professor in Medical Oncology, School of Cancer Sciences, University of Birmingham)

2014-11-13 09:30: Genetic instability - observation and concepts (Paul Edwards, Department of Pathology)

2014-11-18 12:00: Tracking genomic aberrations of the androgen receptor (AR) in castration-resistant prostate cancer (CRPC) (Dr Gerhardt Attard, Royal Marsden Hospital, London)

2014-11-19 12:00: Cell fate in response to anti-mitotic chemotherapeutics (Professor Stephen Taylor, Faculty of Life Sciences, University of Manchester)

2014-11-20 09:30: Development and the cell cycle (Anna Philpott, Department of Oncology, MRC-Hutchison Research Centre)

2014-11-20 13:00: The use of recent advances in electron microscopy to study the ribosome (Venki Ramakrishnan, MRC Laboratory of Molecular Biology)

2014-11-27 09:30: Transcription (Jason Carroll, Cancer Research UK Cambridge Institute)

2014-12-02 12:00: In vivo function-based genomic approaches for cancer drug target discovery  (Professor Daniel Peeper, Head, Division of Molecular Oncology, The Netherlands Cancer Institute)

2014-12-04 09:30: Oncogenes and tumour suppressors (signalling and pathways) (Masashi Narita, Cancer Research UK Cambridge Institute)

2014-12-05 16:15: Max Perutz Lecture 2014: C. elegans surveillance of conserved cellular components to detect and defend pathogen attacks, real or imagined (Gary Ruvkun, MGH Harvard)

2014-12-08 16:00: Traffic control for immune receptors (Silke Robatzek, Sainsbury Laboratory)

2014-12-11 09:30: Tumour Metabolism (Christian Frezza, MRC Cancer Unit)

2014-12-11 13:00: Using RNA-based approaches to identify and characterise cancer genes (Reuven Agami, Netherlands Cancer Institute, Amsterdam)

2014-12-15 16:15: Local and Global Regulation of Meiotic Prophase by Post-Translational Protein Modification (Neil Hunter)

2014-12-16 12:00: Ovarian Cancer in Transition (Mr Douglas Levine, Gynecology Service, Department of Surgery)

2015-01-13 12:00: Explaining the reduction in ovarian cancer mortality 1977 to 2014 (Dr Steven Narod, Director, Familial Breast Cancer Research Unit, Women's College Research Institute, Toronto, Canada)

2015-01-15 09:30: Metastasis (Sakari Vanharanta, Department of Oncology)

2015-01-22 09:30: Senescence, cell death and apoptosis (Masashi Narita, Cancer Research UK Cambridge Institute)

2015-01-26 16:00: Protein folding homeostasis in the endoplasmic reticulum (Professor David Ron, Cambridge Institute for Medical Research (CIMR))

2015-01-27 12:00: “Optimizing Image Guided Radiotherapy for Patient Benefit” (Dr Peter Remeijer, Medical Physicist NKI /Avl, Amsterdam)

2015-01-27 16:15: Title to be confirmed (David Ron, Cambridge University)

2015-01-29 09:30: Stem cells and cancer (Phil Jones, MRC Cancer Unit)

2015-01-29 16:15: Taming a protein destruction machine (Nicolas Thoma, Friedrich Miescher Institute for Biomedical Reearch, Basel, Switzerland)

2015-02-03 12:00: MYC Oncoproteins act as Epigenetic Modifiers (Dr Frank Westermann, Research Group Neuroblastoma Genomics, DKFZ, Heidelberg)

2015-02-05 09:30: Computational biology (Florian Markowetz, Cancer Research UK Cambridge Institute)

2015-02-09 16:00: Role of lateral diffusion barriers in damage confinement and genomic immunity (Professor Dr Yves Barral, Institute of Biochemistry, ETH, Zurich)

2015-02-12 09:30: Computational Biology (Florian Markowetz, Cancer Research UK Cambridge Institute)

2015-02-19 09:30: Genomic technologies (Jason Carroll, Cancer Research UK Cambridge Institute)

2015-02-19 13:00: Cell-specific analysis of tumour-stroma signalling (Dr Claus Jorgensen (CRUK Manchester Institute))

2015-02-19 16:15: Prion propagation and neurotoxicity (Prof. John Collinge, UCL )

2015-02-23 16:00: Axonal signalling endosomes: trafficking, sorting and disease (Dr. Gipi Schiavo, University College London (UCL))

2015-02-25 09:30: in vivo models (Suzanne Turner, Department of Pathology)

2015-03-03 12:00: Systems Biology of Cancer (Professor Jussi Taipale, Department of Biosciences and Nutrition, Karolinska Institute, Sweden )

2015-03-03 16:15: Tbc (Jeff Errington)

2015-03-05 09:30: Epidemiology (Paul Pharoah, CRUK Genetic Epidemiology Unit, Strangeways Research Laboratory)

2015-03-11 16:15: Synthetic Probes for live-cell imaging (Kai Johnsson)

2015-03-16 16:00: Title 'TBA' (Professor Ilan Davis, Oxford University)

2015-03-17 16:15: Remodeling of the erythroid proteome (Dan Finley, Harvard)

2015-03-26 13:00: Towards molecular classification of uterine leiomyomas (Lauri Aaltonen, University of Helsinki, Finland)

2015-03-26 16:15: Insights from a model of breast tumor heterogeneity (Greg Hannon, CRUK, Cambridge)

2015-04-08 16:15: Chromatin unloading of the replicative DNA helicase during replication and repair (Johannes Walter)

2015-04-14 12:00: Defining treatment paradigms in prostate cancer; the UK as a dominant force - past, present, and future (Professor Malcolm Mason, NCRI Prostate Cancer Clinical Studies Group and School of Medicine, Cardiff University)

2015-04-22 13:00: Role of Extracellular Metabolites in Tumor Organization (Dr Carlos Carmona-Fontaine (Memorial Sloan Kettering Cancer Center))

2015-05-05 12:00: Metastatic Stem Cells, TGF-beta signalling and poor-prognosis in CRC (Dr Eduard Batlle (Group Leader, Institute for Research in Biomedicine, Barcelona))

2015-05-12 12:00: "Designing trials to find the right dose" (Dr Adrian Mander - Director of MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge)

2015-05-15 16:15: Regulation of proteasome function in normal and disease states (Professor Alfred Goldberg, Harvard Medical School)

2015-05-19 12:00: DNA damage response: Mechanisms and relevance for cancer development and treatment (Professor Jiri Bartek, The Danish Cancer Society Research Center Genome Integrity Unit, Denmark)

2015-05-21 13:00: New Roles for Lysine Methylation Signaling in Epigenetic and Cancer Regulation (Or Gozani, Stanford University, California)

2015-05-21 16:15: Structural Mechanisms in the Tyrosine Kinases that Initiate Immunological Signaling (Professor John Kuriyan, University of California)

2015-06-02 12:00: 'ECM remodelling during cancer progression' (Dr Janine Erler, Associate Professor - Biotech Research & Innovation Centre (BRIC),Copenhagen )

2015-06-09 12:00: 'Harnessing hypoxia signalling in cancer' (Professor Margaret Ashcroft, Cambridge Cardiovascular)

2015-06-15 16:15: Persister Cells and the Search for Sterilizing Antibiotics (Kim Lewis)

2015-06-18 13:00: From Bioinformatics to Drug Discovery and Clinical Trials:  Targeting Tumour Metabolism To Eradicate Cancer Stem Cells (Michael Lisanti, Institute of Cancer Sciences, Manchester)

2015-06-23 12:00: Interrogating the Architecture of Cancer Genomes (Dr Peter Campbell,  Head of Cancer Genome Project, Wellcome Trust Sanger Institute.)

2015-07-07 11:00: ‘Novel dual-action combination therapy enhances angiogenesis whilst reducing tumour growth and spread’ (Professor Kairbaan Hodivala-Dilke, Professor of Angiogenesis, Deputy Institute Director QMUL )

2015-09-04 16:15: Plasticity of Cancer Cells : Lessons from Glioblastoma (Inder Verma, Salk Institute for Biological Studies)

2015-09-08 12:00: CANCELLED -                                                           "Synergistic effect of radiotherapy and cis-platinum chemotherapy delivered via gold nanoparticles in glioblastoma multiforme" (Dr Sara Piccirillo, Department of Clinical Neurosciences and Alexandra Vaideanu, Deptatment of Engineering )

2015-09-15 12:00: Genomics of radiation responses and radiosensitivity (Professor Michael McKay, North Coast Cancer Institute, NSW, Australia)

2015-09-24 13:00: Genotypic Variability and the Quantitative Proteotype (Ruedi Aebersold; ETH, Zurich)

2015-10-02 15:15: Crick Lecture- The transformative CRISPR-Cas9 genome engineering technology: lessons learned from bacteria (Emmanuelle Charpentier )

2015-10-13 12:00: Melanoma and the translational cycle of innovation in cancer therapeutics (Professor Grant McArthur, Peter MacCallum Cancer Centre, Victoria, Australia)

2015-10-15 09:30: This talk has been postponed (Speaker to be confirmed)

2015-10-19 16:00: 'Do lipid transfer proteins transfer lipid' (Professor Tim Levine, University College London)

2015-10-29 09:30: Tumour natural history, structure and nomenclature (Paul Edwards, Department of Pathology)

2015-10-29 13:00: Imaging and targeting cancer; the multitasking Focal Adhesion Kinase controls cancer cell polarization and immune evasion (Margaret Frame; Edinburgh Cancer Research Centre)

2015-11-05 09:30: Overview of cancer theoretical framework (Paul Edwards, Department of Pathology)

2015-11-09 16:00: "Early endosome motility in cell organization: Insight from a fungal model system" *CANCELLED*CANCELLED*CANCELLED* (Professor Gero Steinberg - University of Exeter)

2015-11-17 11:30: Intrinsic and extrinsic determinants of pancreatic cancer stem cells (Professor Christopher Heeschen, Centre Lead, Centre for Stem Cells in Cancer and Ageing, Barts Cancer Institute, London)

2015-11-19 09:30: This talk is postponed until Dec 16 (Speaker to be confirmed)

2015-11-19 13:00: Origins and clonal evolution of childhood leukaemia (Tariq Enver; University College London)

2015-11-23 16:00: 'Mitotic membrane remodelling by the ESCRT machinery’ (Dr Jeremy Carlton)

2015-11-24 12:00: "Tumor-­induced reprogramming of hepatic metabolism disrupts anti‐tumor immunity” (Dr Tobias Janowitz, Department of Oncology)

2015-11-26 09:30: Tumour natural history, structure and nomenclature (Paul Edwards, Department of Pathology)

2015-11-26 16:15: In the beginning it was dark: Hydrothermal vents and the origin of life (real microbes)  (William Martin, Universität Düsseldorf)

2015-12-03 09:30: Title to be confirmed (Speaker to be confirmed)

2015-12-08 12:00: ‘Combine and conquer: critical pre-clinical and clinical aspects of targeted anti-cancer drugs’ (Dr Udai Banerji, Drug Development Unit, ICR)

2015-12-10 09:30: Reproducible Research (Florian Markowetz, CRUK CI)

2015-12-14 16:15: Milstein Lecture-Phosphoinositide 3-Kinase and Cancer Metabolism (Lewis Cantley, Meyer Cancer Center, Weill Cornell Medicine and New York Presbyterian Hospital, New York)

2015-12-18 13:00: RASA2 is a Novel Tumor Suppressor in Melanoma (Yardena Samuels; Weizmann Institute, Israel)

2016-01-14 09:30: Colorectal cancer and its management (Dr Simon Buczacki)

2016-01-21 09:30: Oesophageal cancer (Professor Rebecca Fitzgerald)

2016-01-21 13:00: Proteomics in cell signaling and cancer research (Matthias Mann, Max-Planck Institute of Biochemistry, Munich and Novo Nordisk Foundation Center for Protein Research, Copenhagen)

2016-01-28 09:30: Cancer metastasis (Dr Sakari Vanharanta)

2016-01-29 16:15: Protein folding homeostasis in the endoplasmic reticulum: tuning a chaperone (David Ron, University of Cambridge)

2016-02-02 16:15: A chemical approach to understanding cell division (Ulrike Eggert)

2016-02-04 09:30: Leukaemia (Dr Brian Huntly)

2016-02-11 09:30: Ovarian cancer (Dr Christine Parkinson)

2016-02-16 11:30: Crick 2016 Lecture-DNA Sequence and the Epigenome Entwined (Adrian Bird)

2016-02-18 09:30: Brain cancer (Professor Richard Gilbertson)

2016-02-18 13:00: DNMT3A in Hematopoietic Stem Cells, Cancer and Ageing (Margaret A. Goodell, Baylor College of Medicine, Houston)

2016-02-22 16:00: To be confirmed (Dr Uwa Paluch, University College London)

2016-02-23 12:00: Innate Genetics and the Tumour Microenvironment Cooperate to Drive Prostate Cancer Aggression (Prof Robert G Bristow, Senior Scientist, Princess Margaret Cancer Centre, Toronto)

2016-02-25 10:30: mRNA stability is substantially dictated by the action of the ribosome (Rachel Green, Johns Hopkins University, School of Medicine)

2016-03-03 16:15: Cell wall deficient (L-form) bacteria: from cell biology to the origins of life (Jeff Errington)

2016-03-09 17:00: “New Developments in Molecular Imaging of Prostate Cancer” (Professor Wim Oyen, Professor of Nuclear Medicine and Molecular Imaging, ICR, London)

2016-03-10 09:30: Prostate cancer (Dr Vincent Gnanapragasam)

2016-03-15 12:00: “Why Determining Pathogenicity in the Age of Precision Medicine, will Require More than Analyzing Genomic Sequences” (Dr Bruce Gottlieb, Lady Davis Institute for Medical Research, Segal Cancer Centre, Jewish General Hospital, Department of Human Genetics, Department of Medicine, McGill University, Montreal, Canada)

2016-03-16 11:00: Structure of TRP channel by single particle cryo-EM (Yifan Cheng)

2016-03-17 09:30: Breast cancer (Professor Carlos Caldas)

2016-03-18 11:00: CRISPR-Cas: origin of adaptive immunity from selfish genetic elements and the evolutionary continuum from Darwin to Lamarck (Eugene Koonin)

2016-03-22 13:00: Tumour suppressor and tumour maintenance genes (Scott Lowe, Memorial Sloan Kettering Cancer Centre, New York)

2016-04-11 16:00: "Mechanotransduction by caveolae: role in cancer"  (Dr. Christophe Lamaze, Institut Curie, France)

2016-04-12 15:00: Charting the human centrosome-cilium landscape (Dr Laurence Pelletier, Lunenfeld-Tanenbaum’s Institute)

2016-04-14 09:30: DNA damage repair (Dr Mark O'Connor, AstraZeneca)

2016-04-14 13:00: Understanding and targeting the ovarian cancer microenvironment (Fran Balkwill, Queen Mary University of London)

2016-04-21 09:30: Use of surgery in breast cancer treatment (Mr Parto Forouhi, Cambridge University Hospitals)

2016-04-25 16:00: "On the recycling of protein sorting receptors: lessons from two key-players of the secretory pathway"   (Professor Jurgen Denecke, University of Leeds)

2016-04-27 11:00: Learning and motivation toggle feed-forward inhibition in the Drosophila mushroom body (Scott Waddell)

2016-04-28 09:30: Treatment of pancreatic cancer (Professor Duncan Jodrell, CRUK CI and Cambridge University Hospitals)

2016-05-03 11:30: “Mechanisms of MYC-driven genome instability” (Jean Gautier, Professor of Genetic and Development, Institute for Cancer Genetics, Columbia University, New York (USA))

2016-05-03 12:00: Mapping cancer origins (Proffessor Richard Gilbertson, Cancer Research UK, Cambridge)

2016-05-04 16:00: Title to be confirmed (Juan Bonifacino, NIH, Bethesda, USA )

2016-05-12 09:30: Treatment of lung cancer (Dr Susan Harden, Cambridge University Hospitals)

2016-05-17 12:00: Future of medicines development: capabilities and how industry is evolving and interacting with academia and the NHS  (Andrew Hughes, Professor of Experimental Cancer Medicine,The Christie NHS Foundation Trust, Manchester)

2016-05-19 09:30: Cancer immunotherapy (Dr Robert Wilkinson, MedImmune)

2016-05-19 13:00: *Please note that this talk has been cancelled and re-scheduled for 2017* (Shelley Berger, University of Pennsylvania)

2016-05-25 15:00: Kendrew lecture- Post-translational regulation of cell signalling (Tony Hunter)

2016-06-02 09:30: Surgery and prostate cancer (Mr Adam Nelson, CRUK CI and Cambridge University Hospitals)

2016-06-02 11:00: Perutz Lecture 2016 (Ron Vale, University of California)

2016-06-06 16:00: 'Mechanics of unconventional myosin motors'  (Claudia Veigel, Department of Cellular Physiology, LMU Munich)

2016-06-09 09:30: Comparative aspects of canine cancer and therapy (Dr Jane Dobson, Dept of Veterinary Medicine, University of Cambridge)

2016-06-09 12:30: Computational Radiotherapy Symposium, 2016: personalised radiotherapy, or how computers can cure cancer (Speakers as detailed in Symposium Programme)

2016-06-10 11:00: Pathological vs Reversible Amyloid (David Eisenberg, University of California)

2016-06-10 11:00: Pathological vs Reversible Amyloid (Prof. David Eisenberg, Dept. Chemistry and Biochemistry, University of California)

2016-06-16 09:30: Common germline genetic variation and risk of cancer (Professor Paul Pharoah, Dept of Oncology, University of Cambridge)

2016-06-28 12:00: Mechanisms of lymphomagenesis: Developmental origins of a paediatric cancer (Dr Suzanne Turner, Department of Pathology)

2016-06-30 13:00: Using Mouse Models to Understand Metastatic Spread and Tumour Heterogeneity (Ben Stanger, Perelman School of Medicine, University of Pennsylvania)

2016-07-01 11:00: TBC (Richard Youle)

2016-07-05 11:30: "Mechanisms of colon cancer initiation, progression and metastasis" (Joerg Huelsken, Associate Professor, Debiopharm Chair in Signal Transduction in Oncogenesis, EPFL, Lausanne)

2016-07-11 16:00: Title to be confirmed (Dr Juan Bonifacino, NIH Intramural Research Programme)

2016-07-12 11:00: TBC (Laurence Pearl, Sussex)

2016-07-13 12:30: Title to be confirmed (Professor Joel Dacks, University of Alberta, Canada )

2016-09-15 13:00: *Please note that this talk has been cancelled* (Nancy Jenkins, Houston Methodist Centre, Texas)

2016-09-23 13:00: Studies into the biology of metastatic disease reveals tRNA-derived fragments that suppress cancer progression (Sohail Tavazoie, The Rockefeller University, New York)

2016-09-27 11:00: TBC (Amita Sehgal)

2016-10-10 16:00: "A role for ER-endosome membrane contact sites in bi-directional cholesterol transport" (Dr Emily Eden - University College London)

2016-10-13 13:00: SEMINAR CANCELLED (Bob Darnell, Rockefeller University, New York and Howard Hughes Medical Institute)

2016-10-24 11:00: Kendrew Lecture- Bacterial Quorum Sensing and its Control  (Bonnie Bassler, Princeton University, USA )

2016-11-07 16:00: 'New insights into ER morphology dysregulation in hereditary spastic paraplegias' (Dr Craig Blackstone, NINDS, USA)

2016-11-15 12:00: Molecular Chaperone Functions in Protein Folding and Quality Control (Ulrich Hartl, max Planck Institute of Biochemistry)

2016-11-17 13:00: The Cancer Cell Map Initiative (Trey Ideker, UC San Diego School of Medicine, La Jolla, CA)

2016-11-29 12:00: CANCELLED - Impact of the Microbiome on cancer and its treatment (Dr Trevor Lawley, Group Leader, Host-Microbiota Interactions Laboratory, Wellcome Trust Sanger Institute)

2016-12-05 16:00: "Drinking problems: Formation and recycling from macropinosomes" (Dr Jason King, The University of Sheffield)

2016-12-15 13:00: What can we learn from Cancer Genomes? (Gad A. Getz, Ph.D, Massachusetts General Hospital Cancer Center and Broad Institute of MIT & Harvard)

2017-01-16 16:00: ‘Functional proteomics of the late endocytic system’ (Dr Geoff Hesketh, Mount Sinai Hospital, Toronto)

2017-01-19 13:00: Overcoming Chromatin Barriers to Elicit Cell Fate Changes (Ken Zaret, Joseph Leidy Professor, Perelman School of Medicine, University of Pennsylvania)

2017-01-23 11:00: Comparative studies of intrinsically disordered proteins (Professor Jane Clarke, Department of Chemistry, University of Cambridge )

2017-01-23 16:00: 'An unexpected role for the golgin giantin in transcriptional control of glycosyltransferase expression' (Professor David Stephens,  School of Biochemistry, University of Bristol)

2017-02-07 11:30: The interaction between tumor hypoxia and DNA methylation  (Dr Bernard Thienpont, VIB-KU Leuven Center for Cancer Biology, KU Leuven, Belgium)

2017-02-09 16:00: Milstein Lecture- Molecular Mechanisms of Synaptic Transmission (Thomas Südhof, Department of Molecular and Cellular Physiology, Stanford)

2017-02-20 16:00: 'The molecular control of the positioning and transport of the endosomal pathway' (Professor Jacques Neefjes, Netherlands Cancer Institute)

2017-02-23 16:00: Epigenomic pathways in cancer and in cancer immunotherapy (Shelley Berger, Epigenetics Institute, Departments of Cell and Developmental Biology, Genetics, Biology, University of Pennsylvania)

2017-03-06 16:00: 'Organizing embryonic contractility in space and time' (François B. Robin, Institute for Biology Paris-Seine)

2017-03-07 11:00: Membrane proteins - the lipid connection (Carol Robinson, university of Oxford)

2017-03-07 11:30: ‘Non-coding RNA - new roles for old players’ (Professor Anders Lund, Biotech Research and Innovation Centre, University of Copenhagen)

2017-03-16 13:00: *PLEASE NOTE THAT THIS TALK HAS BEEN CANCELLED* (Johanna Ivaska, Turku Centre for Biotechnology, Finland)

2017-03-24 11:00: RNA methylation in development and disease  (Michaela Frye, Stem Cell Institute and Department of Genetics, Cambridge)

2017-04-27 11:00: Max Perutz Lecture- Antisense transcription and epigenetic switching (Caroline Dean, John Innes Centre, Norwich)

2017-05-02 11:30: ‘Alterations of the Polycomb machinery in cancers’ (Raphaël Margueron, Curie Institute, Paris)

2017-05-04 13:00: Switching Genes on and off in Erythropoiesis (Doug Higgs, University of Oxford)

2017-05-08 16:00: Mulitispectral imaging to uncover the organelle interactome (Jennifer Lippincott-Schwartz, National Institute of Health, Maryland, USA)

2017-05-15 11:00: Charting the response to DNA damage (Dan Durocher, University of Toronto, Faculty of Medicine)

2017-05-22 16:00: 'Elucidating the role of SNAP29 in post-Golgi trafficking: New insights in to autophagy?’ (Dr Andrew Peden - University of Sheffield)

2017-05-25 13:00: MYC and Metabolic Vulnerabilities of Cancer (Chi Van Dang, MD, PhD, Professor and Director, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine)

2017-05-25 15:00: 'Analyses for Rule-Based Models of Cellular Signalling' (Dr Jean Yang, Assistant Professor,Department of Computer Science, Carnegie Mellon University, Pittsburgh USA )

2017-06-06 11:30: ‘Exploring and exploiting aberrant self-fate programs in leukemia’ (Dr Johannes Zuber, Research Institute of Molecular Pathology (IMP), Vienna, Austria)

2017-06-15 13:00: ****CANCELLED***Mammalian SWI/SNF (BAF) complex structure and function in human cancer (Cigall Kadoch, Ph.D, Dana- Farber Cancer Institute and Harvard Medical School, Boston)

2017-06-20 11:15: LMB Seminar Series-DNA Methylation: From stem cell differentiation to chromatin organisation (Margaret Goodell)

2017-06-26 15:00: Satellite RNAs, Heterochromatin and Cancer: A Novel Mechanism of Induction of Breast Cancer by Loss of BRCA1? (Professor Inder Verma, Salk Institute, San Diego, USA )

2017-07-03 16:00: LMB Seminar Series- Title to follow (Andreas Matouschek, Northwestern University, USA)

2017-07-14 11:00: LMB Seminar Series-RNA quality control and the nuclear RNA exosome (Chris Lima)

2017-09-05 16:00: Integrated structural biology of gene transcription (Patrick Cramer, Max Planck Institute)

2017-09-07 16:00: Crick Lecture-The Surprising Chemistry of Non-enzymatic RNA Replication (Jack Szostack, Harvard, USA )

2017-09-07 16:00: “The OSBP cycle: burning off PI(4)P to transport cholesterol out of the ER” (Professor Bruno Antonny - Institut de Pharmacologie Moléculaire et Cellulaire)

2017-09-18 14:00: ‘The role of Mre11 in DNA double strand break repair  -  myth and facts’ (Professor Shunichi Takeda, Department of Radiation Genetics, Kyoto University)

2017-09-19 11:00: LMB Seminar Series- How T cells control secretion to optimise target cell killing (Gillian Griffiths)

2017-09-21 13:00: ***PLEASE NOTE THIS SEMINAR IS CANCELLED***   (Liz Jaffee, Johns Hopkins Medical Institute, USA)

2017-10-02 11:00: LMB Seminar Series- Stories from the first year of the Central Oxford Structural Microscopy and Imaging Centre - closing in on bacterial protein secretion systems. (Susan Lea)

2017-10-12 13:00: Biomolecular condensates and their implications for neurodegenerative disease (Tony Hyman, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden)

2017-11-02 09:30: Tumour structure and nomenclature (Dr Paul Edwards, Emeritus Reader in Cancer Bioloy)

2017-11-03 11:00: Genomic and cellular integration of bacterial endosymbionts into host cells (John McCutcheon)

2017-11-07 11:30: Metastasis latency: new molecular insights (Roger Gomis, ICREA Research Professor, IRB Barcelona)

2017-11-09 09:30: Overview of the core ideas in cancer research (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2017-11-16 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2017-11-16 13:00: Genomic Approaches to Cancer  (Todd Golub, Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute)

2017-11-23 09:30: Cancer metabolism - a hallmark of cancer (Dr Christian Frezza, MRC Cancer Unit)

2017-11-28 14:00: Exploring and Exploiting the Diversity of Secretory Routes in Mammalian Cells (Franck Perez)

2017-11-30 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology)

2017-12-04 11:00: Localised RNA-based mechanisms underlie neuronal wiring (Christine Holt)

2017-12-05 11:30: ‘Tracking metabolic reprogramming in cancers with PI3K/Akt activation’ (George Poulogiannis, Team Leader, Division of Cancer Biology, Institute of Cancer Research, London)

2017-12-14 09:30: DNA repair:  from mechanistic insights to therapeutic applications in cancer (Professor Steve Jackson, The Gurdon Institute)

2017-12-14 13:00: Dangerous Liaisons between platelets and cancer (Anil Sood, MD - University of Texas, MD Anderson Cancer Centre)

2018-01-15 16:00: Kendrew Lecture- Illuminating biology at the nanoscale and systems scale by imaging  (Xiaowei Zhuang )

2018-01-18 13:00: Mechanosensing and endosomal traffic – new vulnerabilities in breast cancer (Johanna Ivaska, Turku Centre for Biotechnology, University of Turku, Finland)

2018-02-06 14:30: Oxidative Stress Defences in Cancer (Professor Joan Brugge, Louise Foote Pfeiffer Professor of Cell Biology and Director of the Ludwig Centre at Harvard University)

2018-02-22 09:30: Introduction to early detection and tumour development (Professor Paul Pharoah and Dr Jamie Blundell, Early Detection Programme)

2018-03-06 11:30: ‘Instituting Molecular Precision in Localised Prostate Cancer - A Cure for All?’ (Rob Bristow, University Professor of Cancer Studies, Director of MCRC)

2018-03-08 09:30: Imaging techniques and novel tools for early detection and intervention (Dr Sarah Bohndiek and Dr Daniel Munoz-Espin, Early Detection Programme)

2018-03-15 09:30: TALK CANCELLED Targets for drug discovery: from target validation to the clinic (Dr Paul Smith, AstraZeneca)

2018-03-15 13:00: Transcription Factor/Chromatin Interactions: Integrating Genomics and Live Cell Dynamics (Gordon Hager, National Cancer Institute Centre for Cancer Research, USA)

2018-03-15 16:00: LMB Seminar Series-Title to follow (Lukas Kapitein)

2018-03-20 12:00: "Proton Beam Therapy: Current and Future Provision" (Yen-Ching Chang, Consultant in Clinical Oncology, UCHL)

2018-04-12 09:30: Breast cancer - demographics, presentation, diagnosis and patient pathway (Dr Charlotte Coles, Department of Oncology, Cambridge University Hospitals NHS Foundation Trust)

2018-04-12 13:00: RNA Genomics in Health and Disease (Robert B Darnell, MD PhD, The Rockefeller University and Howard Hughes Medical Institute)

2018-04-19 09:30: Demographics, presentation, diagnosis and patient pathway of haematological malignancies (Professor Brian Huntly, Department of Haematology)

2018-04-19 13:00: Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain (Joseph R Ecker PhD, The Salk Institute for Biological Studies, La Jolla, CA)

2018-04-26 16:00: Kendrew Lecture-Electron cryo-microscopy  (Jacques Dubochet)

2018-05-03 09:30: Translational Science: using biomarkers to guide clinical development in oncology (Dr Andy Pierce, AstraZeneca)

2018-05-03 11:00: ‘Accelerating the translation of mutational signatures' (Dr Serena Nik-Zainal, Wellcome Sanger Institute)

2018-05-17 13:00: Clonal evolution of cancer: lessons from the mouse (Allan Balmain, UCSF Helen Diller Comprehensive Family Cancer Centre)

2018-05-23 11:00: LMB Seminar Series-Title to follow (Titia De Lange Rockefeller)

2018-05-29 16:00: LMB Seminar Series-Title to follow (Michael Hall)

2018-05-31 09:30: 5 selfish reasons to work reproducibly (Dr Florian Markowetz, Group Leader, Cancer Research UK Cambridge Institute, University of Cambridge)

2018-06-05 11:00: ‘Cellular Plasticity in Cancer:  driving force and therapeutic target’ (Professor Thomas Brabletz, Department of Experimental Medicine, University Erlangen-Nuernberg)

2018-06-14 09:30: Paediatric malignancies: an overview (Dr Amos Burke, Department of Paediatric Haematology, Oncology and Palliative Care, Cambridge University Hospitals NHS Foundation Trust)

2018-06-15 10:30: ‘Nuclear Mechanopathology & Early Cancer Diagnostics’ (Professor GS Shivashankar, Deputy Director, Mechanobiology Institute, National University of Singapore)

2018-06-21 09:30: Frontiers in paediatric cancer research (Dr Suzanne Turner, Department of Pathology)

2018-06-28 09:30: Colorectal cancer. Part 1. Presentation, Diagnosis and Intervention. Part 2. Cellular signalling networks in colon cancer and the models to study them - a basic research perspective (Mr Simon Buczacki, CRUK Cambridge Institute and Dr Marc de la Roche, Department of Biochemistry)

2018-06-28 13:00: Functional Genomics to Study Cancer (David Sabatini, Whitehead Institute)

2018-06-28 16:00: LMB Seminar Series - Kinetochore Structure (Steve Harrison)

2018-07-05 09:00: Lung Cancer. Part 1. Patient pathway and Intervention. Part 2. Lung Cancer: Futurescape (Dr Robert Rintoul, CUH and Papworth NHS Foundation Trusts, and Dr Frank McCaughan, Department of Biochemistry)

2018-07-10 13:00: Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Cancer (Cigall Kadoch, Dana-Farber Cancer Institute and Harvard Medical School)

2018-07-12 09:30: Diagnostics and patient pathways in pancreatic cancer (Mr Raaj Praseedom, Cambridge University Hospitals NHS Foundation Trust)

2018-07-19 09:30: Research frontiers and new therapeutic strategies in pancreatic cancer (Dr Tobias Janowitz, Department of Oncology)

2018-07-26 09:30: MicroRNAs as circulating biomarkers in cancer (Dr Matthew Murray, Department of Pathology)

2018-09-20 16:00: Evidence that sub-cellular oscillators may time and execute organelle biogenesis (Jordan Raff)

2018-09-27 13:00: *** Cancelled*** (Ana Pombo, MDC Berlin)

2018-10-24 11:00: Light Sleep (Gero Miesenboeck)

2018-10-25 13:00: Towards cancer screening using circulating DNA (Y M Dennis Lo, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China)

2018-11-01 16:00: LMB Seminar Series-Mycobacterium tuberculosis infection of host cells in time and space (Max Gutierrez)

2018-11-15 11:00: Reconstructing Tissue Architecture by Single Cell Genomics (Sarah Teichmann)

2018-11-15 13:00: Bridging DNA methylation dynamics and electronic health records to understand the non-coding genome (Emily Hodges, Vanderbilt Genetics Institute, USA)

2018-11-20 11:00: LMB Seminar Series-Title to follow (Carrie Partch)

2018-11-29 09:30: Introduction to the biology of metastasis (Dr Sakari Vanharanta, MRC Cancer Unit )

2018-11-29 16:00: Perutz Lecture- How synapses work:  Architecture and mechanism of neurotransmitter receptors and transporters (Eric Gouaux)

2018-12-03 11:00: LMB Seminar Series-Solving a 3D jigsaw with 1000 pieces - Structure and assembly of the nuclear pore complex (Martin Beck)

2018-12-04 11:30: ‘Executable Disease Networks: Reconstruction, Topology, Dynamics’ (Anna Niarakis, Université Paris-Saclay, Evry, France)

2019-01-03 09:30: The integrated approach to the diagnosis of haematological malignancies (Dr Mike Scott, Department of Haematology, Cambridge University Hospitals NHS Foundation Trust)

2019-01-15 11:30: THIS SEMIAR IS NOW CANCELLED  -                                                            'Cell Plasticity in Colon Carcinogenesis' (Professor Florian Greten, Institute for Tumor Biology and Experimental Therapy, Frankfurt)

2019-01-17 09:30: Systemic Anticancer Therapy (Dr Bristi Basu, Department of Oncology, Cambridge University Hospitals NHS Foundation Trust)

2019-01-30 11:00: LMB Seminar Series-Epigenetic inheritance in mammals (Anne Ferguson Smith, Department of Genetics, Wellcome Trust Senior Investigator)

2019-01-31 13:00: Genome Architecture Mapping: discovering 3D genome topology in rare cell types (Ana Pombo, Berlin Institute for Medical Systems Biology, Max Delbrueck Center for Molecular Medicine, Berlin, Germany; Humboldt University of Berlin, Berlin, Germany)

2019-02-07 09:30: Lecture Cancelled (Louisa Bellis (University of Cambridge))

2019-02-21 13:00: Epigenetic control of malignant melanoma (Emily Bernstein, Icahn School of Medicine at Mount Sinai)

2019-02-27 12:00: ‘Multi-dimensional cancer-immune cell interaction during metastasis’ (Xiang Zhang, Baylor College of Medicine, Houston, USA)

2019-02-28 09:30: Liquid biopsy biomarkers for early detection; general principles and specific examples (Dr Charlie Massie, Early Detection Programme)

2019-02-28 16:00: LMB Seminar Series - Stem cells, regeneration and organoid cultures (Meritxell Huch, Wellcome Sir Henry Dale Fellow, Member of the Department of Physiology, Development and Neuroscience)

2019-03-05 16:00: LMB Seminar Series Milstein Lecture - Intracellular Membrane Contact Sites, Lipid Dynamics and Neurodegeneration (Pietro De Camilli Departments of Neuroscience and Cell Biology, Howard Hughes Medical Institute, Kavli Institute for Neuroscince, Yale University School of Medicine)

2019-03-08 11:30: LMB Seminar Series - Animating Molecular Biology (Janet Iwasa, Assistant Professor, Biochemistry Department, University of Utah)

2019-03-14 09:30: Lecture Cancelled (Lecture Cancelled)

2019-03-14 10:30: LMB Seminar Series - ANNA KARENINA AND THE GENETICS OF COMPLEX DISEASE: DE NOVO MUTATIONS IN SCHIZOPHRENIA (Mary-Claire King, human geneticist professor, University of Washington)

2019-03-21 09:30: Demographics, Diagnosis and Treatment Pathways in Haematological Malignancies (Professor Brian Huntly, Department of Haematology)

2019-03-21 13:00: A Deep Dive into the Genome of Hypoxic Tumours (Robert Bristow, Manchester Cancer Research Research Centre, University of Manchester)

2019-03-27 00:00: LMB Seminar Series: Title tbc (Julie Ahringer, PhD FMedSci, Director, Wellcome Senior Research Fellow, Professor of Genetics and Genomics, Member of the Department of Genetics)

2019-03-27 00:00: LMB Seminar Series: Title tbc (Julie Ahringer, PhD FMedSci, Director, Wellcome Senior Research Fellow, Professor of Genetics and Genomics, Member of the Department of Genetics)

2019-03-28 09:30: The bone marrow microenvironment in myeloid malignancies (Dr Simon Mendez-Ferrer (University of Cambridge))

2019-04-03 00:00: LMB Seminar Series: Title tbc (Gerry Rubin, Vice President, HHMI, and Executive Director, Janelia Research Campus)

2019-04-03 00:00: LMB Seminar Series: Title tbc (Gerry Rubin, Vice President, HHMI, and Executive Director, Janelia Research Campus)

2019-04-05 11:00: LMB Seminar Series - Pathogen restriction and host specificity: insights from the human pathogen Salmonella Typhi (Jorge Galan, PhD, DVM, Lucille P. Markey Professor of Microbial Pathogenesis and Professor of Cell Biology; Chair, Department of Microbial Pathogenesis)

2019-04-09 11:30: ‘Mammary epithelial cell fate and tumour initiation at the single cell resolution’ (Walid Khaled, Department of Pharmacology, University of Cambridge)

2019-04-10 11:00: LMB Seminar Series - Factors and Functions of ER Membrane Contact Sites (Gia Voeltz PhD, HHMI Investigator and Professor University of Colorado at Boulder)

2019-04-11 13:00: Fire and Water are Good Servants, But Bad Masters (Tak Mak, Princess Margaret Cancer Centre, University Health Network, University of Toronto)

2019-04-26 13:00: Cellular Conversations that Control Cancer (Thea D Tlsty, University of California San Francisco (UCSF) Helen Diller Comprehensive Cancer Center and Department of Pathology, 513 Parnassus Avenue, San Francisco, CA 94143-0511)

2019-04-29 11:00: LMB Seminar Series - CryoEM of proton pumping macromolecular machines (John Rubinstein)

2019-05-03 11:00: LMB Seminar Series - Synthesis and hydrolysis of the gram-positive cell wall: revisiting old models with new data (David Rudner, Dept. of Microbiology and Immunobiology, Harvard Medical School)

2019-05-07 11:30: ‘New protagonists of the tumour microenvironment’ (Dr Ilaria Malanchi, Tumour-Host Interaction Lab,Francis Crick Institute, London )

2019-05-09 09:30: Kidney cancer: the most lethal urological malignancy (Dr Grant Stewart, Department of Surgery, Cambridge University Hospitals NHS Foundation Trust)

2019-05-16 10:30: LMB Seminar Series - Modifications of RNA: their function and role in cancer  (Tony Kouzarides, PhD FRS FMedSci, Professor of Cancer Biology, Cancer Research UK Gibb Fellow, Director of the Milner Therapeutics Institute, Member of the Department of Pathology)

2019-05-18 00:00: LMB Seminar Series: Title tbc (Nieng Yan, Professor of Molecular Biology, Princeton University)

2019-05-23 16:00: LMB Seminar Series - The 100,000 genomes project and beyond (Tim Hubbard, Professor of Bioinformatics & Head of Department, King’s College London)

2019-05-28 11:00: LMB Seminar Series - Towards a mechanistic understanding of  cellular processes by cryo-EM (Gaia Pigino, Research Group Leader at the MPI-CBG)

2019-05-30 09:30: Brain tumours: demographics, presentation, diagnosis, treatment (Mr Thomas Santarius, Cambridge University Hospitals NHS Foundation Trust)

2019-06-11 11:30: ‘Next-Generation Biopsies in Gastrointestinal Cancers’ (Dr Nicola Valeri, Institute of Cancer Research and The Royal Marsden NHS Trust)

2019-06-11 12:00: ‘Why Standard Naming and Pixel-based Contouring/Voluming are important to research in the radiation Oncology area’ (Prof Andrew Miller, Radiation Oncologist, Illawarra Cancer Care Centre, Wollongong, NSW Australia / Adjunct Professor of Informatics, School of Informatics, University of Wollongong  )

2019-06-14 10:30: LMB Seminar Series: Folding and assembly of newly synthesized proteins revealed by ribosome profiling (Bernd Bukau, Center for Molecular Biology of Heidelberg University and German Cancer Research Center)

2019-06-18 11:00: LMB Seminar Series - Structural and mechanistic studies of key components in DNA damage signalling and repair (Xiaodong Zhang)

2019-06-20 09:30: The childhood cancer genome (Dr Sam Behjati - Research Fellow in Medical Sciences and Wellcome Trust Intermediate Clinical Fellow, Department of Paediatrics and WTSI)

2019-06-20 13:00: Perturbation biology: data-driven executable models of cellular processes and the design of combination therapy (Chris Sander, Dana-Farber Cancer Institute and Harvard Medical School)

2019-06-27 09:30: Cellular signalling networks in colon cancer and the models to study them.  A basic research perspective (Dr Marc de la Roche, Lecturer - Department of Biochemistry)

2019-06-28 12:00: What next for your career in science?  (Rebecca Aarons, Jenny Gallop, Emma Gleave)

2019-07-01 11:30: ‘Combining omics data and biological knowledge to understand and treat cancer’ (Julio Saez-Rodriguez, Institute for Tumor Biology and Experimental Therapy Frankfurt)

2019-07-10 11:30: ‘Combining omics data and biological knowledge to understand and treat cancer’ (Julio Saez-Rodriguez, Heidelberg University, Faculty of Medicine & EMBL- Heidelberg University Molecular Medicine Partnership Unit)

2019-07-11 09:30: Diagnostics and patient pathways in pancreatic cancer (Dr Raaj Praseedom - Consultant HPB-Transplant Surgeon, Lead clinician for the East of England Specialist HPB Specialist Multidisciplinary Team.)

2019-07-18 16:00: LMB Seminar Series - Francis Crick Lecture - Innovation by Evolution: Bringing New Chemistry to Life (Frances Arnold, California Institute of Technology, Pasadena, U.S.A.)

2019-07-23 11:00: LMB Seminar Series - Antibodies against Ebola and Lassa: A Global Collaboration (Erica Ollmann Saphire, Professor Department of Immunology and Microbiology California Campus)

2019-07-25 09:30: MicroRNAs as circulating biomarkers in cancer (Dr Matthew Murray - Academic Consultant Paediatric Oncologist)

2019-09-03 11:30: ‘Treatment of cancer by inhibition of mtDNA gene expression’ (Nils-Göran Larsson, MD, PhD, Professor, Department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet, Stockholm )

2019-09-12 10:30: LMB Seminar Series - Organelle contact sites: a new layer in the organization of Eukaryotic cells (Benoit Kornmann, Associate professor – Dept. of Biochemistry, Oxford University, and C.W. Maplethorpe Tutorial Fellow in Bio-chemistry – St-Hugh’s College, Oxford University)

2019-09-26 13:00: TET-family dioxygenases, immune responses and cancer  (Anjana Rao, La Jolla Institute for Allergy and Immunology)

2019-10-01 11:30:  ‘Activation of transcription factor Nrf2 as a strategy to restore the cellular redox and protein homeostasis’ (Professor Albena Dinkova-Kostova,Jacqui Wood Cancer Centre, Division of Cellular Medicine, University of Dundee  )

2019-10-03 10:30: LMB Seminar Series - Kendrew Lecture - How a ubiquitin-like protein brings ubiquitylation to life (Brenda Schulman, Director at the Max Planck Institute of Biochemistry)

2019-10-11 13:00: Transcriptional dependencies in cancer (Christopher Vakoc, Cold Spring Harbor Laboratory)

2019-10-24 09:30: Tumour structure and nomenclature  (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2019-10-31 09:30: Overview of the core ideas in cancer research  (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2019-10-31 13:00: Forcing tumor initiation and progression (Valerie M Weaver, University of California, San Francisco)

2019-11-07 09:30: The mutations that drive cancer  (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2019-11-14 09:30: Introduction to the biology of metastasis (Dr Sakari Vanharanta, MRC Cancer Unit)

2019-11-21 09:00: Cancer metabolism, a hallmark of cancer- NB 9am start time (Dr Christian Frezza, MRC Cancer Unit)

2019-11-21 13:00: Cancer and ageing: Rival demons?   (Judith Campisi, Buck Institute for Research on Ageing and Lawrence Berkeley National Laboratory)

2019-11-21 16:00: LMB Seminar Series: Folding and assembly of newly synthesized proteins revealed by ribosome profiling (Bernd Bukau, Center for Molecular Biology of Heidelberg University and German Cancer Research Center)

2019-11-28 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology)

2019-12-03 11:30: ‘Cell Plasticity in Colon Carcinogenesis’ (Professor Dr Florian Greten, Institute for Tumor Biology and Experimental Therapy, Frakfurt)

2019-12-06 11:00: LMB Seminar Series: Host factors that shape influenza evolution. (Wendy Barclay)

2019-12-12 09:30: Exploring the role of the tumour microenvironment: what do other cells do? (Dr Jacqui Shields - MRC Cancer Unit)

2020-01-09 10:00: Systemic anticancer therapy (Dr Gary Doherty (University of Cambridge))

2020-01-16 09:30: Cancer Immunotherapy (Dr Christine Parkinson, Department of Oncology, Cambridge University Hospitals NHS Foundation Trust)

2020-01-23 09:30: A scientists guide to the art of radiation therapy & Neurosurgery for the Oncologist (Dr Raj Jena, Department of Onocology and Mr Adel Helmy, Department of Clinical Neuroscience CUH NHS Foundation Trust)

2020-01-27 11:00: Milstein LMB Seminar Series: Stem Cells in Silence, Action and Cancer  (Elaine Fuchs, Rebecca C. Lancefield Professor Investigator, Howard Hughes Medical Institute )

2020-02-04 13:00: Single cell whole genome sequencing approaches to model evolution in cancer (Sohrab Shah, MSKCC)

2020-02-13 09:30: The AKT inhibitor Capivasertib (AZD5363): From Discovery to Clinical Proof of Concept (Dr Barry Davies - Director, Clinical and Translational Scientific Alliances, AstraZeneca)

2020-02-20 09:30: The challenges in therapeutic targeting of the RAF-MEK-ERK signalling pathway (Dr Simon Cook, Babraham Institute)

2020-02-25 16:00: LMB Seminar: Mitochondrial Behaviour (Jodi Nunnari, Distinguished Professor, Department of Molecular and Cellular Biology, Univeristy of California, Davis)

2020-02-26 11:00: Perutz LMB Seminar Series: How our chromosomes are replicated (John Diffley, Associate Research Director, the Francis Crick Institute, London, UK)

2020-02-27 09:30: Oncological Imaging: introduction and non-radionuclide techniques & radionuclide techniques (Dr. Ferdia Gallagher Department of Radiology & Dr Luigi Aloj, Department of Nuclear Medicine, Cambridge University Hospitals NHS Foundation Trust)

2020-03-05 09:30: Introduction to the early detection of cancer and novel interventions (Professor Rebecca Fitzgerald, Early Detection Programme)

2020-03-12 09:30: The development of cancer risk susceptibility models and application to early detection (Professor Antonis Antoniou, Early Detection Programme)

2020-03-19 09:30: Biological and Clinical Features of High Grade Serous Ovarian Cancer (Dr James Brenton, CRUK Cambridge Institute)

2020-03-26 09:30: Breast cancer: demographics, presentation, diagnosis & patient pathway (Dr Richard Baird, Department of Oncology)

2020-04-02 09:30: The microenvironment in the myeloid malignancies (Dr Simon Mendez-Ferrer, Department of Haematology)

2020-04-07 11:30: CANCELLED - “Cancer genomics: from chromatin structure to new therapeutic targets” (Professor Elisa Oricchio (EPFL, Zurich))

2020-04-09 09:30: DNA repair: from mechanistic insights to therapeutic applications in cancer (Professor Steve Jackson, The Gurdon Institute)

2020-04-23 09:30: Mathematical and evolutionary approaches to cancer (Jamie Blundell, Early Detection Programme, Dept of Oncology)

2020-04-23 13:00: **** This seminar has been cancelled **** (Jim Norman, Cancer Research UK Beatson Institute)

2020-04-30 09:30: Epidemiology of Ovarian Cancer (Professor Paul Pharoah, Professor of Genetic Epidemiology )

2020-05-07 09:30: The role of transcription factors in cancer (Prof Jason Carroll, CRUK Cambridge Institute)

2020-05-14 09:30: Treatment of kidney cancer (Mr Grant Stewart, Cambridge University Hospitals)

2020-05-21 09:30: Paediatric Malignancies (Dr Amos Burke, Clinical Consultant - Department of Paediatric Haematology, Oncology and Palliative Care)

2020-05-21 13:00: **** This seminar has been cancelled **** (Ramanujan S Hegde)

2020-05-28 09:30: Artificial Intelligence for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities (Dr Namshik Han, Head of Computational Biology, Milner Therapeutics Institute)

2020-06-04 09:30: The clinical and biological basis of prostate cancer - from diagnosis to personalised therapy (Mr Vincent Gnanapragasam, Department of Surgery, Cambridge University Hospitals NHS Foundation Trust)

2020-06-11 09:30: The promise of proton therapy in Paediatric tumours  (Dr Thankamma Ajithkumar, Cambridge University Hospitals NHS Foundation Trust)

2020-06-18 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities (Dr Daniel Munoz-Espin, Group Leader, Department of Oncology.)

2020-06-25 09:30: Lung Cancer: Part 1. Patient pathway and intervention.  Part 2. Lung Cancer: Futurescape (Dr Robert Rintoul -Clinical Consultant, Cancer Research UK Cambridge Institute and Dr Frank McCaughan-Wellcome Trust Intermediate Clinical Fellow / Honorary Consultant,Department of Biochemistry School of Clinical Medicine )

2020-06-25 13:00: **** This seminar has been cancelled **** (Marica Haigis, Harvard Medical School)

2020-07-02 09:30: The biology and fundamental management of colorectal cancer (Mr Simon Buczacki, Dept Haematology (University of Cambridge))

2020-07-09 09:30: Viral Oncology (Professor John Doorbar, Department of Pathology)

2020-07-16 09:30: Diagnostics and patient pathways in pancreatic cancer ( Mr Raaj Praseedom, Consultant HPB-Transplant Surgeon, Lead clinician for the East of England Specialist HPB Specialist Multidisciplinary Team)

2020-09-08 11:00: Study virus assembly and host interactions in vitro and in cells by cryoEM and cryoET  (Peijun Zhang, Professor of Structural Biology and Wellcome Trust Investigator, University of Oxford )

2020-09-17 17:30: Therapeutic Opportunities in Glycoscience (Carolyn Bertozzi, Stanford University)

2020-09-22 16:00: RNP granules in health and disease (via Zoom) (Roy Parker, Investigator, Howard Hughes Medical Institute, Executive Director, BioFrontiers Institute, Distinguished Professor and Cech-Leinwand Endowed Chair of Biochemistry, University of Colorado Boulder,  USA)

2020-10-15 13:00: Targeting the Tumour Microenvironment (Clare Isacke, The Institute of Cancer Research)

2020-10-22 09:30: Tumour structure and nomenclature  (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2020-10-29 09:30: Overview of the core ideas in cancer research  (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2020-11-02 16:00:  How is electrical signal generated?  (Nieng Yan, Shirley M. Tilghman Professor of Molecular Biology, Princeton University, USA)

2020-11-03 16:00: The African killifish: a vertebrate model to understand aging and ‘suspended animation' (Anne Brunet, Michele and Timothy Barakett Professor of Genetics, Stanford University, USA)

2020-11-05 09:30: The mutations that drive cancer  (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2020-11-12 09:30: Introduction to the biology of metastasis  (Dr Sakari Vanharanta, MRC Cancer Unit )

2020-11-19 09:30: Cancer metabolism, a hallmark of cancer (Dr Christian Frezza, MRC Cancer Unit)

2020-11-19 13:00: The remote control of gene expression: enhancer function in development and disease (Wendy Bickmore, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh)

2020-11-26 09:30: DNA repair: from mechanistic insights to therapeutic applications in cancer (Professor Steve Jackson, The Gurdon Institute)

2020-11-26 11:00: Sir Martin Wood Prize Lecture: The emerging world of microbial rhodopsins in photobiology (Keiichi Inoue, Associate Professor, The Institute for Solid State Physics, The University of Tokyo)

2020-12-03 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology)

2020-12-08 16:00: Translation defects and neurological disease (Susan L Ackerman, PhD.  Professor, Cellular and Molecular Biology  Steven W. Kuffler Chair of Biology  University of California San Diego USA/HHMI)

2020-12-10 09:30: Exploring the role of the tumour microenvironment: what do the other cells do? (Dr Jacqui Shields, MRC Cancer Unit)

2020-12-17 10:00: Systemic anti-cancer therapy   (Dr Gary Doherty, Cambridge University Hospital NHS Foundation Trust)

2021-01-07 09:30: The bone marrow microenvironment in myeloid malignancies (Dr Simón Méndez-Ferrer, Department of Haematology)

2021-01-14 09:30: Cancer Immunotherapy (Dr Christine Parkinson,  Dept of Oncology, CUH NHS Foundation Trust)

2021-01-21 09:30: A scientist’s guide to the art of radiation therapy & Neurosurgery for the Oncologist (Dr Raj Jena, Dept of Oncology  & Mr Adel Helmy, Dept of Clinical Neuroscience, CUH NHS Foundation Trust)

2021-01-21 13:00: Molecular Imaging for the Improved Visualization and Treatment of Cancer (Jason Lewis, MSKCC)

2021-01-28 09:30: Clinical treatment and cancer stem cell biology in malignant glioma (Dr Harry Bulstrode,  Dept of Clinical Neuroscience, CUH NHS Foundation Trust)

2021-02-11 09:30: The AKT inhibitor capivasertib (AZD5363): from discovery to clinical proof concept (Dr Barry Davies,  Director, Clinical Translation Scientific Alliances, AstraZeneca)

2021-02-18 09:30: The challenges in therapeutic targeting of the RAF-MEK-ERK signalling pathway (Dr Simon Cook FRSB,   Senior Group Leader, Babraham Institute)

2021-02-25 09:30: Oncological Imaging: i. Introduction & Non-radionuclide techniques ii. Radionuclide techniques (Prof Ferdia Gallagher,  Dept of Radiology,    &  Dr Luigi Aloj,  Dept of Nuclear Medicine, CUH NHS Foundation Trust)

2021-02-25 13:00: Mechanisms and consequences of pancreatic cancer stromal evolution (Mara Sherman, Oregon Health & Science University)

2021-03-02 16:00: Rules of engagement: molecular arms races between host and viral genomes (Dr. Harmit Singh Malik, Professor, Division of Basic Sciences & HHMI Investigator, Fred Hutchinson Cancer Research Center)

2021-03-04 09:30: Mathematical and evolutionary approaches to cancer (Dr Jamie Blundell,  Early Detection Programme, Dept of Oncology)

2021-03-11 09:30: Early detection and treatment of lethal prostate cancer.  (Dr Charlie Massie,   Dept of Oncology and Dr Harveer Dev,  Clinical Lecturer Early Detection Programme)

2021-03-16 11:00: LMB Seminar: Functions of Ribosome-Associated Chaperones in Health and Disease   (Prof. Dr. Elke Deuerling, Chair of Molecular Microbiology, University of Konstanz, Germany)

2021-03-18 09:30: Paediatric malignancies: an overview (Dr Amos Burk    Clinical Consultant, Dept of Paediatric Haematology, Oncology and Palliative Care)

2021-03-18 13:00: Regulation of Protein Degradation in Cancer and Effect on Tumor Immunity (X. Shirley Liu, Dana-Farber Cancer Institute and Harvard University )

2021-03-25 09:30: Breast Cancer – demographics, presentation, diagnosis and patient pathway (Dr Richard Baird,  Dept of Oncology, CUH NHS Foundation Trust)

2021-04-15 09:30: Lung Cancer. Part 1. Patient pathway and Intervention;  Part 2: Futurescape (Dr Robert Rintoul, Royal Papworth Hospital NHS Foundation Trust  and Dr Frank McCaughan, Wellcome Trust Intermediate Clinical Fellow, Dept of Biochemistry)

2021-04-20 11:00: LMB Seminar: Molecular views into cellular functions by in-cell cryo-electron tomography (Dr Julia Mahamid, Group Leader, EMBL Heidelberg, Germany)

2021-04-22 09:30: Epidemiology of Ovarian Cancer  (Professor Paul Pharoah, Centre for Cancer Genetic Epidemiology)

2021-04-27 16:00: Perutz Lecture 2021: The coming of age of de novo protein design  (Professor David Baker, Director of the Institute for Protein Design, University of Washington, USA )

2021-04-29 09:30: The role of transcription factors in cancer ( Dr Jason Carroll, CRUK Cambridge Institute)

2021-05-06 09:30: Artificial intelligence for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities. (Dr Namshik Han, Head of Computational Biology, Milner Therapeutics Institute)

2021-05-13 09:30: Kidney cancer: the most lethal urological malignancy (Prof Grant Stewart,  Dept of Surgery, Cambridge University Hospitals NHS Foundation Trust)

2021-05-20 09:30: Frontiers in paediatric cancer research (Dr Suzanne Turner, Dept of Pathology, Cambridge University)

2021-05-20 13:00: Quality control of proteins orphaned in the cytosol (Ramanujan S Hegde, MRC LMB)

2021-05-25 16:00: LMB Seminar: Systemic regulation of brain aging and function (Tony Wyss-Coray, D. H. Chen Professor II, Stanford University, USA)

2021-05-27 09:30: The promise of proton therapy in paediatric tumours  (Dr Thankamma Ajithkumar, Consultant Clinical Oncologist, Cambridge University Hospitals NHS Foundation Trust)

2021-06-03 09:30: Biological and clinical features of high grade serous ovarian cancer ( Dr James Brenton, CRUK Cambridge Institute)

2021-06-10 09:30: Understanding Myc transcription (Dr Cathy Wilson, Department of Pharmacology)

2021-06-17 09:30: Diagnostics and patient pathways in pancreatic cancer ( Mr Raaj Praseedom, Consultant HPB-Transplant Surgeon, Lead clinician for the East of England Specialist HPB Specialist Multidisciplinary Team)

2021-06-17 13:00: Cancelled (Marcia Haigis, Harvard Medical School)

2021-06-22 11:00: LMB Seminar: Mechanisms of centriole assembly (Pierre Gönczy, Swiss Federal Institute of Technology Lausanne (EPFL), Switzerland)

2021-06-24 09:30: It takes a village: targeting the non-cancerous neighbours to fight pancreatic cancer (Dr Giulia Biffi;  Cancer Research UK Cambridge Institute)

2021-06-29 16:00: LMB Seminar: Membrane Mechanics: cryo-EM insights and challenges (Adam Frost, Associate Professor, Biochemistry and Biophysics, UCSF, USA)

2021-07-01 09:30: In vivo functional screens for modelling cancer initiation and progression (Dr Eric Rahrmann, Cancer Research UK Cambridge Institute)

2021-07-06 11:00: LMB Seminar: The biomass distribution on Earth (Ron Milo, Professor, Department of Plant and Environmental Sciences, Weizmann Institute of Science, Israel)

2021-07-15 09:30: From another lens: An anthropological perspective on cancer and care in the UK. (Dr Ignacia Arteaga Dept of Social Anthropology )

2021-07-22 09:30: Viral Oncology (Professor John Doorbar, Department of Pathology)

2021-07-27 16:00: Using stem cell technology to combat age-related neurodegenerative diseases (Sally Temple PhD, Scientific Director, Neural Stem Cell Institute, USA)

2021-09-02 13:00: Cancelled (Nikolaus Rajewsky, MDC Berlin)

2021-09-16 13:00: Cell Polarity and Organoids: New Pathways and Models for Translational Research and Cancer Immunology (Senthil Muthuswamy, Harvard Medical School)

2021-10-13 14:30: LMB Kendrew Lecture (part 1): Using AI to accelerate scientific discovery  (Demis Hassabis, Founder & CEO DeepMind, AlphaFold project lead)

2021-10-13 16:00: LMB Kendrew Lecture (part 2): Highly accurate protein structure prediction with AlphaFold (John Jumper, Research scientist and AlphaFold lead)

2021-10-14 15:00: Priming the Immune System to Provoke Checkpoints: The Path to Maintaining the Immunotherapy Momentum  (Elizabeth M Jaffee, John Hopkins)

2021-10-19 11:00: LMB Seminar: Biomolecular condensates and their implications for physiology and disease (Tony Hyman, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany)

2021-10-21 09:30: Tumour structure and nomenclature  (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2021-10-28 09:30: Overview of the core ideas in cancer research (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2021-10-29 13:00: Metabolic rewiring drives invasion and metastasis in mammary carcinoma (Jim Norman, Cancer Research UK Beatson Institute)

2021-11-02 16:00: Interplay between tissue tension and tumor immunity (Valerie Weaver, Director of the Center for Bioengineering and Tissue Regeneration and Professor in the Department of Surgery, UCSF, USA)

2021-11-04 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2021-11-11 09:30: Introduction to the biology of metastasis   (Dr Sakari Vanharanta, MRC Cancer Unit)

2021-11-15 11:00: Crick Lecture 2021: Human Immune Responses to SARS-CoV-2 Infection or Vaccination (Michel C. Nussenzweig, Zanvil A. Cohn and Ralph M. Steinman Professor, The Rockefeller University, New York, USA)

2021-11-18 09:30: Systematic anti-cancer therapy  ( Dr Gary Doherty, CUH NHS Foundation Trust)

2021-11-18 13:00: Seminar cancelled (Amos Tanay, Weizmann Institute of Science)

2021-11-25 09:30: DNA repair: translating mechanistic insights towards new cancer therapies. (Professor Steve Jackson, The Gurdon Institute )

2021-11-30 11:00: Milstein Lecture 2021: Organoids to model human diseases (Hans Clevers, Professor in Molecular Genetics, Hubrecht Institute, Utrecht, The Netherlands)

2021-12-02 09:30: Care and Cure:an Introduction to  Philosophy of Medicine (Professor Jacob Stegenga,  Department of History and Philosophy of Science:)

2021-12-09 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology)

2021-12-16 09:30: Oncological imaging: 1: Introduction and non-radionuclide techniques; 2: Radionuclide techniques (Prof Ferdia Gallagher, Department of Radiology (Cambridge University)  & Dr Luigi Aloj, Department of Nuclear Medicine, (Cambridge University Hospitals))

2021-12-16 13:00: Decoding and Recoding the Opposing Roles of Interferon and Pattern Recognition Receptor Signaling in Cancer Immunotherapy (Andy J. Minn, MD, PhD, Abramson Family Cancer Research Institute at the University of Pennsylvania)

2022-01-06 09:30: A scientist’s guide to the art of radiation therapy & Neurosurgery for the Oncologist (Dr Raj Jena, Dept of Oncology & Mr Adel Helmy, Dept of Clinical Neuroscience (CUH NHS Foundation Trust))

2022-01-13 09:30: Viral Oncology (Professor John Doorbar, Department of Pathology)

2022-01-20 09:30: Mathematical and evolutionary approaches to cancer  (Dr Jamie Blundell,  Early Detection Programme, Dept of Oncology )

2022-02-17 09:30: The challenges in therapeutic targeting of the RAF-MEK-ERK signalling pathway (Dr Simon Cook FRSB,   Senior Group Leader, Babraham Institute)

2022-02-24 09:30: Artificial Intelligence for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities (Dr Namshik Han, Head of Computational Biology, Milner Therapeutics Institute)

2022-03-03 09:30: Breast Cancer- demographics, presentation, diagnosis and patient pathway  (Dr Richard Baird,  Dept of Oncology, CUH NHS Foundation Trust)

2022-03-10 09:30: Paediatric malignancies - an overview (Dr Amos Burk    Clinical Consultant, Dept of Paediatric Haematology, Oncology & Palliative Care)

2022-03-17 09:30: The bone marrow microenvironment in myeloid malignancies (Dr Simon Mendez-Ferrer Dept of Haematology, Cambridge Stem Cell Institute)

2022-03-17 13:00: Title to be confirmed (Karen Vousden, The Crick Institute)

2022-03-24 09:30: Epidemiology of Ovarian Cancer  (Prof Paul Pharoah, Centre for Cancer Genetic Epidemiology)

2022-03-29 16:00: Max Perutz Lecture 2022: Therapeutic Opportunities in Glycoscience (Carolyn Bertozzi, Anne T. and Robert M. Bass Professor of Chemistry, Baker Family Director, Stanford ChEM-H, Howard Hughes Medical Institute Investigator, Stanford University)

2022-03-31 09:30: In vivo functional screens for modelling cancer initiation and progression (Dr Eric Rahrmann, Cancer Research UK Cambridge Institute)

2022-04-01 13:00: Deciphering the regulation and regulatory function of oncogenic transcription factors using time-resolved functional genetics (Johannes Zuber, IMP, Vienna BioCentre)

2022-04-07 09:30: Biological and Clinical features of high grade serous ovarian cancer (Dr James Brenton, CRUK Cambridge Institute)

2022-04-19 11:00: LMB Seminar:  Engineering Organoid Development (Professor Matthias Lutolf, Roche Institute for Translational Bioengineering, Basel, Switzerland and Laboratory of Stem Cell Bioengineering, EPFL, Switzerland)

2022-04-28 09:30: The role of transcription factors in cancer (Dr Jason Carroll; CRUK Cambridge Institute)

2022-04-28 13:00: Title to be confirmed (Fatima Metcha-Grigoriou, Institut Curie)

2022-05-05 09:30: The promise of proton therapy in paediatric tumours  (Dr Thankamma Ajithkumar, Consultant Clinical Oncologist, Cambridge University Hospitals NHS Foundation Trust)

2022-05-12 09:30: Frontiers in paediatric cancer research (Dr Suzannne Turner, Dept of Pathology)

2022-05-12 16:00: Kendrew Lecture 2022: Chemogenetic and optogenetic technologies for probing molecular and cellular networks (Alice Ting - Professor of Genetics, of Biology and, by courtesy, of Chemistry, Stanford University, USA and Chan Zuckerberg Biohub Investigator )

2022-05-19 09:30: Cancer resistance in the naked mole-rat, a tale of transformation (Prof Ewan St John Smith; Dept of Pathology)

2022-05-19 13:00: Cell Plasticity and Lineage Commitment in Liver Tumorigenesis (Lars Zender, University Hospital Tuebingen)

2022-05-20 09:00: Aaron Klug Memorial Symposium (Various - see Further Information)

2022-05-26 09:30: Understanding Myc Transcription (Dr Cathy Wilson, Department of Pharmacology)

2022-05-26 11:00: LMB Seminar - Using connectomes to accelerate studies of the neuronal control of behavior in Drosophila (Gerald M. Rubin, Senior Group Leader, Janelia Research Campus, HHMI, LMB Fellow)

2022-06-09 09:30: Hh signalling and the anti-tumour immune response: biology and new treatment opportunities (Dr Maike de La Roche, CRUK Cambridge Institute)

2022-06-16 09:30: CANCELLED   The impact of environmental factors on cancer ( Dr Elisabete Silva,  Brunel University London)

2022-06-23 09:30: Cell differentiation and tumour initiation - two sides of the coin ( Dr Walid Khaled Dept of Pharmacology/ Cambridge Stem Cell Institute )

2022-06-30 09:30: Kidney cancer: The most lethal urological malignancy (Prof Grant Stewart,  Dept of Surgery, Cambridge University Hospitals NHS Foundation Trust)

2022-07-07 09:30: Pancreatic Cancer: Challenges, Models and Therapeutic Opportunities (Dr Giulia Biffi;  Cancer Research UK Cambridge Institute)

2022-07-14 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities (Dr Daniel Muñoz-Espin; Department of Oncology)

2022-07-14 12:00: Mitochondria and Cancer - lessons learned dissecting cellular and molecular interactions (Marica Haigis, Harvard Medical School)

2022-07-21 09:30: Lung Cancer. Part 1. Patient pathway and Intervention;  Part 2: Futurescape (Professor Robert Rintoul (Papworth Hospital and Dr Frank McCaughan (Dept of Biochemistry))

2022-07-26 10:00: Milstein Lecture 2022 - mRNA Cancer Vaccines (Ugur Sahin, M.D., Professor Translational Oncology & Immunology, Johannes Gutenberg University Mainz, Co-founder, CEO BioNTech, Germany)

2022-07-26 11:30: Milstein Lecture 2022 - Project Lightspeed – The discovery of the first Covid-19 mRNA Vaccine (Özlem Türeci, M.D., Professor Personalized Cancer Immunotherapy, Johannes Gutenberg University Mainz, Co-founder, CMO BioNTech, Germany)

2022-09-08 11:00: LMB Seminar: Encoding tissue morphogenesis with genetics, mechanics and geometry (Professor Thomas Lecuit, Group leader at IBDM and Turing Center for living systems, Marseille. Professor at Collège de France, Paris)

2022-09-15 13:00: This seminar has been cancelled - we apologise for any inconvenience caused.  Thank you (Nikolaus Rajewsky, MDC Berlin)

2022-09-27 11:00: Regulation of mRNA translation and decay (David Bartel, Professor of Biology, MIT, HHMI, and Whitehead Institute)

2022-10-13 13:00: Probing the rate limitation of a cancer driver mutation (Hans-Reimer Rodewald, DKFZ)

2022-10-18 11:00: LMB Seminar: Cryo-ET reveals sarcomere structures at molecular resolution (Prof. Dr. Stefan Raunser, Director, Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund)

2022-10-20 09:30: Tumour  pathology, structure and nomenclature   (Dr. Paul Edwards (University of Cambridge))

2022-10-27 09:30: Core ideas in cancer research 1: genes and genetic instability (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2022-11-03 09:30: Core ideas in cancer research 2: cell biology (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2022-11-03 11:00: Crick Lecture 2022: Neurobiology of Social and Sickness Behaviors (Catherine Dulac, Higgins Professor of Molecular and Cellular Biology, Lee and Ezpeleta Professor of Arts and Sciences, Howard Hughes Medical Institute Investigator, Department of Molecular and Cellular Biology, Harvard University)

2022-11-09 11:30: New Frontiers in PKA Signaling (Susan Taylor, Professor of Chemistry and Biochemistry and a Professor of Pharmacology at the University of California, San Diego)

2022-11-10 09:30: The mutations that drive cancer (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2022-11-17 09:30:  Simulating medicine: testing- speculations about medical science and clinical practice   (Prof Jacob Stagenga, Department of History and Philosophy of Science: )

2022-11-17 13:00: This seminar has been cancelled - we apologise for any inconvenience caused.  Thank you (Louis Chesler, ICR)

2022-11-24 09:30: Cancer stem cells, evolution and heterogeneity (Professor Brian Huntly, Department of Haematology)

2022-11-29 16:00: LMB Seminar: Mechanism and regulation P element transposition in Drosophila  (Donald Rio, Professor of Biochemistry, Biophysics and Structural Biology, Dept. of Molecular and Cell Biology, University of California, Berkeley, USA)

2022-12-01 09:30: Cancer metabolism, a hallmark of cancer (Prof Christian Frezza, CECAD Research Center, University Hospital Cologne)

2022-12-08 09:30: DNA repair: translating mechanistic insights towards new cancer therapies.  (Prof Steve Jackson; The Gurdon Institute )

2022-12-08 10:00: LMB Seminar: Structural basis of how the BIRC6/SMAC complex regulates apoptosis and autophagy (Tim Clausen, Research Institute of Molecular Pathology (IMP))

2022-12-08 13:00: Title to be confirmed (Serena Nik-Zainal, MRC Cancer Unit)

2022-12-15 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities (Dr Daniel Muñoz-Espin; Department of Oncology / Early Cancer Institute)

2023-01-12 09:30: The role of transcription factors in cancer. (Prof Jason Carroll, CRUK Cambridge Institute)

2023-01-17 11:00: LMB Seminar: Engineering a bacteria for lung therapy (Prof. Luis Serrano)

2023-01-19 09:30: In vivo functional screens for modelling cancer initiation and progression  (Dr Eric Rahrmann, Cancer Research UK Cambridge Institute)

2023-01-26 09:30: The development of cancer risk prediction models and their applications to prevention and early detection ( Prof Antonis Antoniou,  Dept of Public Health and Primary Care)

2023-01-26 10:30: Milstein Lecture 2023: Understanding the Hox timer by Using mammalian Pseudo-Embryos (Denis Duboule, Collège de France, Paris France, Federal Institute of Technology (EPFL), Lausanne, Switzerland)

2023-02-02 09:30: Cancer virology   (Professor John Doorbar, Department of Pathology)

2023-02-16 09:30: TALK CANCELLED   (Prof Rebecca Fitzgerald, Early Cancer Institute)

2023-02-23 09:30: Experimental cancer genetics  (Dr David Adams, Wellcome Sanger Institute)

2023-02-23 13:00: Tumor genomes shed light into somatic mutational processes and cancer vulnerabilities (Nuria Lopez-Bigas)

2023-03-02 09:30: Hh signalling and the anti-tumour immune response: biology and new treatment opportunities (Dr Maike de La Roche, CRUK Cambridge Institute)

2023-03-09 09:30: How do cells acquire drug resistance mutations? (Dr Jon Houseley, Babraham Institute)

2023-03-16 09:30: Immune Regulation in Inflammation and Cancer (Dr Rahul Roychoudhuri)

2023-03-23 09:30: The two hit hypothesis and other simple theories of cancer (Dr Jamie Blundell, Early Cancer Institute)

2023-03-23 13:00: A DNA methylation atlas of normal human cell types (Tommy Kaplan, the Hebrew University of Jerusalem)

2023-03-30 09:30: Artificial Intelligence in Cancer (Dr Michael Boemo, Dept of Pathology)

2023-04-20 09:30: Machine learning: applications to cancer ( Dr Mireia Crispin, Department of Oncology)

2023-04-20 13:00: Stressing out our immune system in chronic infection and cancer (Susan Kaech)

2023-04-27 09:30: Toolkit in Cancer Research: in vitro modelling and spatial phenotyping (Dr John Lizhe Zhuang; Early Cancer Institute and Dept of Oncology)

2023-05-04 09:30: Shedding light on tumour physiology ( Dr Mariam-Eleni Oraiopoulou; research associate VISION Lab  CRUK Cambridge Institute )

2023-05-04 13:00: Small Cell Lung Cancer from biology to biomarkers (Caroline Dive, CRUK Manchester Institute)

2023-05-09 09:30: Kidney cancer (Dr James Jones; Cambridge University Hopitals NHSFT)

2023-05-09 09:30: Kidney cancer (Dr James Jones; Cambridge University Hospitals NHSFT)

2023-05-09 16:00: LMB Seminar: The Extraordinary Life and Legacy of Sir John C. Kendrew (Professor Paul Wassarman, Mount Sinai, New York)

2023-05-11 09:30: Understanding Myc Transcription (Dr Catherine Wilson; Dept of Pharmacology)

2023-05-15 11:00: LMB Seminar: Tissue genomics: High throughout tools for measuring and perturbing tissues (Fei Chen)

2023-05-18 09:30: Single cell RNA seq. and application in cancer research (Dr. Walid Khaled  and Dr Sara Pensa (Cambridge Stem Cell Institute))

2023-05-18 13:00: Seminar cancelled (Polly Fordyce, Stanford University)

2023-05-25 09:30: A scientists guide to the art of radiation therapy & Neurosurgery for the oncologist  (Dr Raj Jena Dept of Oncology and Cambridge University Hospitals; Mr Adel Helmy, Dept of Clinical Neuroscience)

2023-06-01 09:30: Cancer resistance in the naked mole-rat: tales of transformation and more! ( Prof Ewan St John Smith, Dept of Pharmacology)

2023-06-08 09:30: Biological and Clinical features of high grade serous ovarian cancer (Prof James Brenton, CRUK Cambridge Institute and Cambridge University Hospitals NHSFT)

2023-06-12 11:00: LMB Seminar: Blending Proteins: Democratising Access to Beautiful Molecular Landscapes (Brady Johnston)

2023-06-15 09:30: Nutrition and cancer prevention  (Prof Martin Wiseman, World Cancer Research Fund International and Visiting Professor in Human Nutrition Southampton University )

2023-06-15 13:00: Title to be confirmed (Nikolaus Rajewsky)

2023-06-19 11:00: LMB Seminar: What do we know about (your) antibodies? Novel insights from novel techniques in mass spectrometry (Albert Heck, University of Utrecht, The Netherlands)

2023-06-22 09:30: Kidney cancer: an introduction (Dr James Jones; Cambridge University Hopitals NHSFT)

2023-06-29 09:30: The promise of proton therapy in paediatric tumours  (Dr Thankamma Ajithkumar, Consultant Clinical Oncologist, Cambridge University Hospitals NHS Foundation Trust)

2023-07-03 11:00: LMB Seminar: Single-molecule studies reveal the dynamics of replication origin licensing (Stephen P. Bell, MIT, Dept. of Biology and HHMI)

2023-07-06 09:30: Early stage cancer clinical trials (Dr Simon Pacey, Cambridge University Hospital, Dept of Oncology)

2023-07-10 11:00: LMB Seminar: Decoding the role of solute carriers in health and disease (Professor Simon Newstead)

2023-07-13 09:30: Pancreatic Cancer - The clinical challenge;   Why the microenvironment matters during progression and treatment (Dr Giulia Biffi and Dr Bristi Basu; CRUK Cambridge Institute / Oncology Dept and Cambridge University Hospitals)

2023-07-20 09:30: Paediatric malignancies (Dr Amos Burke    Clinical Consultant, Dept of Paediatric Haematology, Oncology & Palliative Care)

2023-07-27 09:30: Curing cancer with AI – hype or hope? (Prof Richard Gilbertson, CRUK Cambridge Institute and Director of CRUK Cambridge Centre)

2023-09-12 11:00: LMB Seminar: Talking to cells: biomolecular ultrasound for imaging and control of cellular function in intact organisms (Mikhail G. Shapiro, Max Delbrück Professor, Caltech)

2023-09-18 13:00: Updates and opportunities offered by whole genome sequencing on the Cambridge Biomedical Research Campus (Serena Nik-Zainal, Early Cancer Institute, University of Cambridge)

2023-10-02 13:00: How cilia signal (Jeremy Reiter, UCSF)

2023-10-19 09:30: Tumour  pathology, structure and nomenclature ( Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2023-10-26 09:30: Core ideas in cancer research 1: genes and genetic instability (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2023-10-30 11:00: Kendrew Lecture 2023: Cryo-electron tomography or the power of seeing the whole picture (Wolfgang Baumeister, Max Planck Institute of Biochemistry, Germany)

2023-11-02 09:30: Core ideas in cancer research 2: cell biology (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2023-11-06 13:00: First in human evaluation of CDK9 inhibition with KB-0742 in solid tumors (Richard Cutler PhD, Kronos Bio, Inc.)

2023-11-07 11:00: LMB Seminar: Pharmacological Adaptation of Proteostasis to Ameliorate Aging-associated Degenerative Diseases (Jeffery W. Kelly, The Scripps Research Institute)

2023-11-09 09:30: The mutations that drive cancer  (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2023-11-16 09:30: Precision oncology: a philosophical perspective (Dr Benjamin Chin-Yee, Haematologist (Western University, Canada);  MA in History and Philosophy of Science.)

2023-11-20 11:00: Perutz Lecture 2023: Decoding the protein dance (Prof. Dr. Paola Picotti, Associate Professor for Molecular Systems Biology, Institute of Molecular Systems Biology, ETH Zurich)

2023-11-20 13:00: Seminar Cancelled (Karen Vousden)

2023-11-23 09:30: DNA repair: translating mechanistic insights towards new cancer therapies.  (Prof Steve Jackson, CRUK Cambridge Institute )

2023-11-27 11:00: Crick Lecture 2023: Innovating metagenomics to explore the strange world of archaeal extrachromosomal elements (Jill Banfield, University of California, Berkeley)

2023-11-30 09:30: Cancer stem cells, evolution and heterogeneity  (Professor Brian Huntly, Department of Haematology)

2023-12-04 11:00: LMB Seminar: Power to the protein: analyse, signal and protect with bacterial superglues (Professor Mark Howarth, University of Cambridge)

2023-12-07 09:30: Hypoxia, HIFs and cancer (Prof Margaret Ashcroft, Department of Medicine )

2023-12-11 11:00: *CANCELLED* LMB Seminar: Alpha-Synuclein and its aggregation in neurodegenerative diseases (Prof Maria Grazia Spillantini, Professor of Molecular Neurology, University of Cambridge)

2023-12-14 09:30: Cancer metabolism, a hallmark of cancer   (Prof Christian Frezza  CECAD Research Center, University Hospital Cologne)

2023-12-14 11:30: Mapping stromal heterogeneity and immunosuppression in breast cancer (Fatima Mechta-Grigoriou)

2024-01-11 09:30: Hh signalling and the anti-tumour immune response: biology and new treatment opportunities (Dr Maike de La Roche, Cancer Research UK Cambridge Institute )

2024-01-15 11:00: LMB Seminar: From regeneration to homeostasis: tissue-scale decision making (Pros. Prisca Liberali)

2024-01-18 09:30: Cancer Immunology and Immunotherapy (Prof Rahul Roychoudhuri, Department of Pathology)

2024-01-25 09:30: Steroid hormone regulation of  cancer immunity ( Dr Bidesh Mahata, Department of Pathology)

2024-01-29 11:00: LMB Seminar: The allosteric landscape of a protein (Ben Lehner FRS FMedSci, Head of Generative and Synthetic Genomics, Wellcome Sanger Institute, Cambridge, UK, ICREA Professor, Systems and Synthetic Biology, CRG, Barcelona, ES)

2024-02-01 09:30: Redefining metastasis: what we know and where we are going ( Dr Eric Rahrmann, Cancer Research UK Cambridge Institute. )

2024-02-05 11:00: LMB Seminar: Cell volume and dry mass across time scales in cultured mammalian cells: from milliseconds in migrating and circulating cells to homeostasis during cycles of growth and division (Matthieu Piel, Institut Curie)

2024-02-15 12:00: "Meet the Expert": How to survive and thrive as an entrepreneur  (Dr Jason Mellad, Co-Founder and CEO of Startcodon.  )

2024-02-15 13:00: Deciphering Developmental Disorders  (Matthew Hurles, Sanger Institute)

2024-02-22 09:30: The development of cancer risk prediction models and their applications to prevention and early detection  ( Prof Antonis Antoniou,  Department of Public Health and Primary Care.  )

2024-02-26 11:00: CANCELLED: LMB Seminar: New therapeutic modalities based on pseudo-natural peptides, products, and neobiologics (Prof. Hiroaki Suga, Ph.D, The University of Tokyo, Graduate School of Science, Department of Chemistry)

2024-02-29 09:30: Frontiers in paediatric cancer research  (Professor Suzanne Turner, Department of Pathology)

2024-03-07 09:30: Fluorogenetic interrogation of epigenetic pathways (Dr Iva Tchasovnikarova,  Gurdon Institute and Department of Biochemistry. )

2024-03-14 09:30: The role of transcription factors in cancer (Prof Jason Carroll, CRUK Cambridge Institute)

2024-03-21 09:30: Clonal haematopoiesis, early detection and pre-leukemia to leukemia development (Prof Elisa Laurenti,   Wellcome-MRC Cambridge Stem Cell Institute.  )

2024-04-04 11:00: LMB Seminar: Biosynthesis and degradation of the underappreciated green polymer cyanophycin (Martin Schmeing, Ph.D., James McGill Professor, Department of Biochemistry and Directeur, Centre de recherche en biologie structurale, McGill University)

2024-04-11 09:30: Understanding the cancer genome base-by-base (Dr David Adams, Wellcome Sanger Institute)

2024-04-11 11:00: LMB Seminar: Super-resolution imaging of transcription in living cells (Ibrahim Cissé, Department of Biological Physics, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany)

2024-04-18 09:30: The role of radiation in cancer care: a spotlight on cancers of the oesophagus, head and neck   (Dr Gill Barnett; Dept of Oncology and Strangeways Research Laboratory; Dr Christopher Jones, Dept of Oncology and Cambridge University Hospitals )

2024-04-18 13:00: Towards Rational Combination Therapies: Understanding tumor evolution during therapy response  and resistance (Anna Obenauf, IMP Vienna)

2024-04-25 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities (Dr Daniel Munoz Espin, Early Cancer Institute and Dept of Oncology)

2024-05-02 09:30: Biological and clinical insights from genome-wide association studies of cancer (Dr Siddhartha Kar, Early Cancer Institute and Department of Oncology)

2024-05-03 13:00: Modelling and Targeting the Tumour Microenvironment of High-Grade Serous Ovarian Cancer (Professor Frances Balkwill OBE, FMedSci, Centre for Tumour Microenvironment, Barts Cancer Institute, Queen Mary University of London, UK)

2024-05-07 16:00: LMB Seminar: Evading ageing: Mitochondrial and proteostatic adaptations in oocytes  (Elvan Boke,  Group Leader, Centre for Genomic Regulation (CRG), Barcelona, Spain )

2024-05-09 09:30: Cancer resistance in the naked mole-rat: tales of transformation and more! (Prof Ewan St John Smith,  Department of Pharmacology)

2024-05-16 09:30: Cancer virology (Prof John Doorbar, Department of Pathology)

2024-05-16 13:00: Title to be confirmed (KJ Patel, MRC WIMM, Oxford)

2024-05-23 09:30: Targeted Protein Degradation tools for novel therapeutic strategies in cancer (Dr Catherine Lindon, Dept of Pharmacology)

2024-05-30 09:30: The two-hit hypothesis and other mathematical models of cancer (Dr Jamie Blundell, Early Cancer Institute and Department of Oncology)

2024-06-03 11:00: LMB Seminar: Identification of alternative pathways for metabolism or cell death using haploid genetics (Thijn Brummelkamp, Netherlands Cancer Institute/Oncode Institute)

2024-06-06 09:30: TODAY'S TALK CANCELLED DUE TO SICKNESS Machine learning: applications to cancer (Dr Mireia Crispin Ortuzar, Early Cancer Institute and Department of Oncology)

2024-06-13 09:30: Does reconstructing the past history of kidney cancer help predict clinical behaviour? (Dr Tom Mitchell; Early Cancer Institute and Dept of Surgery)

2024-06-17 11:00: LMB Seminar: Mechanosensing in cancer invasion and metastasis (Laura M Machesky, Sir William Dunn Professor of Biochemistry, University of Cambridge)

2024-06-20 09:30: Early cancer trials (Dr Simon Pacey, Cambridge University Hospitals, Dept of Oncology)

2024-06-20 14:00: The Biology of Drug Resistance in Lung Cancer (Katerina Politi, Yale School of Medicine)

2024-06-27 09:30: A scientists guide to the art of radiation therapy   and   Neurosurgery for the oncologist  ( Dr Raj Jena,  Cambridge University Hospitals and Department of Oncology;  Mr Adel Helmy, Department of Clinical Neuroscience)

2024-07-01 11:00: LMB Seminar: Separate yet connected: mitochondrial and nuclear genome stability (Agnel Sfeir)

2024-07-04 09:30: Pancreatic cancer - the clinical challenge;  Why the microenvironment matters during pancreatic cancer progression and treatment (Dr Bristi Basu, Cambridge University Hospitals NHS FT and Dept of Oncology; Dr Giulia Biffi, Cancer Research UK Cambridge Institute)

2024-07-11 09:30: Translating the biology of epigenetics into clinical applications for cancer (Dr Harveer Dev,  Early Cancer Institute, Cambridge University Hospitals and Department of Oncology.)

2024-07-18 09:30: Leveraging the Virtuous Cycle: Clinical Trials - Translational Science - Basic Science (Prof Jean Abraham;  Director, Cambridge Breast Cancer Research Unit, Cambridge University Hospitals  and Department of Oncology)

2024-09-05 13:00: Identifying therapeutic opportunities in the metabolic crosstalk between the tumour and the host (Professor Karen Vousden, The Francis Crick Institute)

2024-09-09 11:00: LMB Seminar: Laser phase plate in cryo-EM and cryo-ET (Holger Müller)

2024-09-16 11:00: LMB Seminar: Linking nanoscale synapse organization, function and plasticity (Dr Daniel Choquet - University of Bordeux Institute for Interdisciplinary Neuroscience and the Bordeaux Imaging Center)

2024-09-23 11:00: LMB Seminar: Feedback control of mitosis in the context of the kinetochore (Andrea Musacchio, Director, Department of Mechanistic Cell Biology, Max-Planck-Institute of Molecular Physiology)

2024-09-30 11:00: Francis Crick Lecture 2024: Neuronal circuits for body movements - In Person Only (Silvia Arber)

2024-10-03 10:30: CANCELLED - LMB Seminar: RNA Meets DNA: Dangerous Liaisons in the Genome (Karlene Cimprich - Stanford University School of Medicine, Department of Biochemistry)

2024-10-14 11:00: LMB Seminar: Molecular mechanisms that regulate the first cell fate decisions in human development - In Person Only (Kathy Niakan)

2024-10-17 13:00: Senescent secretome shenanigans:  Differential therapeutic benefit for breast cancer dictated by distinct extracellular vesicle-mediated inflammatory response (Dr Karen Crasta, Principal Investigator at the National University of Singapore, Centre for Healthy Longevity and Department of Physiology. )

2024-10-24 09:30: Tumour  pathology, structure and nomenclature (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2024-10-31 09:30: Core ideas in cancer research 1: genes and genetic instability (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2024-11-04 11:00: 2024 John Kendrew Lecture: Wiring Specificity of Neural Circuits - In Person Only (Liqun Luo)

2024-11-07 09:30: Core ideas in cancer research 2: cell biology (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2024-11-11 11:00: 2024 Max Perutz Lecture: Antisense Modulation of RNA Splicing for Rare Disease Therapy - In Person Only (Adrian R. Krainer, Ph.D., St. Giles Foundation Professor, Cold Spring Harbor Laboratory)

2024-11-14 09:30: The mutations that drive cancer  (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2024-11-14 13:00: Seminars in Cancer (Andrea Sottoriva, ICR and Human Technopole, Milan)

2024-11-14 13:00: Endogenous Formaldehyde as a driver for clonal haematopoiesis and in pervasive DNA base adduction  (Professor KJ Patel, Director of the MRC Molecular Haematology Unit and MRC WIMM at the University of Oxford)

2024-11-21 09:30: Hypoxia, HIFs and cancer (Prof Margaret Ashcroft, Department of Medicine )

2024-11-25 11:00: LMB Seminar: Metabolism, Cellular Decisions and the Language That Unites Them (Jared Rutter)

2024-11-28 09:30: DNA repair: translating mechanistic insights towards new cancer therapies.  (Prof Sir Steve Jackson, CRUK Cambridge Institute )

2024-12-05 09:30: Machine learning: applications to cancer (Dr Mireia Crispin Ortuzar, Early Cancer Institute and Department of Oncology)

2024-12-05 13:00: Origins and consequences of gene dosage mutations in cancer (Professor Sam Aparicio, University of British Columbia)

2024-12-09 11:00: 2024 Milstein Lecture: 11am Centrioles in homeostasis, disease and evolution: tiny organelles, multiple and critical functions - IN PERSON ONLY (Mónica Bettencourt Dias)

2024-12-12 09:30: Understanding the cancer genome base-by-base (Dr David Adams, Wellcome Sanger Institute)

2024-12-13 13:00: Understanding Mechanisms of Microenvironment-Mediated Therapy Resistance (Professor Michael Hemann, Koch Institute for Integrative Research at MIT)

2024-12-19 09:30: Cancer metabolism, a hallmark of cancer   (Prof Christian Frezza  CECAD Research Center, University Hospital Cologne)

2025-01-09 09:30: Cancer stem cells, evolution and heterogeneity  (Professor Brian Huntly, Department of Haematology & Cambridge Stem Cell Institute)

2025-01-16 09:30: Hh signalling and the anti-tumour immune response: biology and new treatment opportunities (Dr Maike de La Roche, Cancer Research UK Cambridge Institute )

2025-01-23 09:30: Cancer Immunology and Immunotherapy (Prof Rahul Roychoudhuri, Dept of Pathology)

2025-01-23 13:00: Telomere to mitochondria signaling prevents age-associated cancer initiation (Jan Karlseder, Salk Institute for Biological Studies)

2025-01-27 11:00: LMB Seminar - The immune system of bacteria - IN PERSON ONLY (Rotem Sorek, Weizmann Institute of Science)

2025-01-30 09:30: Steroid hormone regulation of  cancer immunity (Dr Bidesh Mahata, Dept of Pathology)

2025-02-10 11:00: LMB Seminar - Alpha-Synuclein and its aggregation: Past, Present and Future (Maria Grazia Spillantini, University of Cambridge, Dept of Clinical Neurosciences)

2025-02-13 09:30: Frontiers in paediatric cancer research  (Prof Suzanne Turner; Dept of Pathology)

2025-02-19 11:00: The Francis Crick Lecture 2025 - The DNA Quadruplex Helix (Shankar Balasubramaniam, University of Cambridge)

2025-02-20 09:30: The role of transcription factors in cancer (Prof Jason Carroll, CRUK Cambridge Institute)

2025-02-27 09:30: Systems immunology and variation in the human immune system (Professor Adrian Liston)

2025-03-03 11:00: LMB Seminar - Cryo-OrbiSIMS – high resolution mass spectrometry imaging in the native biological state (Ian Gilmore, National Physical Laboratory)

2025-03-06 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities (Dr Daniel Munoz Espin, Early Cancer Institute and Dept of Oncology)

2025-03-10 11:00: LMB Seminar - One or two membranes? Investigating the transition between monoderm and diderm cell envelopes across the Tree of Bacteria - IN PERSON ONLY (Simonetta Gribaldo, Intstitut Pasteur)

2025-03-13 09:30: Cancer virology (Prof John Doorbar, Department of Pathology)

2025-03-20 09:30: Biological and clinical insights from genome-wide association studies of cancer (Dr Siddhartha Kar, Early Cancer Institute )

2025-03-20 13:00: Understanding and intercepting somatic clonal evolution in blood (George Vassiliou, CSCI Cambridge)

2025-03-27 09:30: Revealing the Unseen: AI's Role in Novel Target Discovery  for High Unmet Needs Areas Through Multi-Omics Integrationce for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities (Dr Namshik Han, Head of Computational Research & AI, Milner Therapeutics Institute)

2025-04-03 09:30: Mutational signatures: From bytes to bedside (Professor Serena Nik-Zainal)

2025-04-07 11:00: LMB Seminar - Higher Order Transient structures and the principle of dynamic connectivity in membrane signaling (Rod MacKinnon - Rockefeller University)

2025-04-07 15:00: LMB Seminar - How small molecules rescue a folding disease:  principles learned from the ion channel CFTR  (Jue Chen - Rockefeller University)

2025-04-08 11:30: LMB Seminar - Transmission of Misfolded Proteins in Neurodegenerative Disorders: A Common Mechanism of Disease Progression (Virginia Man-Yee Lee, Center for Neurodegenerative Disease Research, University of Pennsylvania)

2025-04-10 09:30: Myc in Cancer and Regeneration (Dr Catherine Wilson, Dept of Pharmacology)

2025-04-24 10:00: César Milstein Lecture: Mechanisms driving the rapid evolution of genomes (David Pellman - Dana-Faber Cancer Institute, Harvard University)

2025-04-24 13:00: Homologous recombination deficiency in cancer: prevalence, diagnosis and novel targeting approaches (Simon Powell, MSKCC)

2025-05-01 09:30: Targeted Protein Degradation tools for novel therapeutic strategies in cancer (Dr Catherine Lindon, Dept of Pharmacology)

2025-05-08 09:30: Decoding genomic chaos - a pancancer compendium of chromosomal instability (Professor Florian Markowetz, Cancer Research UK Cambridge Institute)

2025-05-15 09:30: The two-hit hypothesis and other mathematical models of cancer (Prof Jamie Blundell; Early Cancer Institute)

2025-05-19 11:00: LMB Seminar - Blueprints of Life: Understanding the Sex Chromosomes (James Turner, The Francis Crick Institute)

2025-05-22 09:30: Oncogene-induced senescence and tumour initiation (Prof Masashi Narita, Cancer Research UK Cambridge Institute)

2025-05-29 09:30: From lab to clinic: an introduction to translational research  (Dr James Jones; Cambridge University Hospitals and  Department of Oncology )

2025-06-05 09:30: Early cancer trials (Dr Simon Pacey, Cambridge University Hospitals, Dept of Oncology)

2025-06-12 09:30: The role of radiation in cancer care: a spotlight on cancers of the oesophagus, head and neck   (Dr Gill Barnett and Dr Christopher Jones, Cambridge University Hospital & Dept of Oncology )

2025-06-19 09:30: Overview of treatment for non-small cell lung cancer (Dr Huiqi Yang and Dr Nicola Thompson, Cambridge University Hopitals Trust)

2025-06-19 13:00: Hope in Hard Places: Bridging the Cancer Care Gap in Resource Limited Settings: Lessons and Innovations from the Uganda Cancer Institute (Dr Nixon Niyonzima, Uganda Cancer Institute)

2025-06-26 09:30:  Transmissible cancers (Prof Elizabeth Murchison,  Department of Veterinary Medicine.  )

2025-06-26 10:00: LMB Seminar - Fast and slow pathways of ribosomal subunit association (Joachim Frank, Columbia University)

2025-06-30 11:00: LMB Seminar - Cellular response to genetic change (Andy Fire - Stanford University School of Medicine)

2025-07-03 09:30: The promise of proton therapy in Paediatric tumours (Dr Thankamma Ajithkumar,  Cambridge University Hospitals and Department of Oncology.  )

2025-07-07 11:00: CANCELLED LMB Seminar - In vitro reconstitution of minimal cytoskeletal systems (Marileen Dogterom - TU Delft, Delft University of Technology)

2025-07-10 09:30: Pancreatic cancer - the clinical challenge;  Why the microenvironment matters during pancreatic cancer progression and treatment (Dr Kiran Purushothaman, Cambridge University Hospitals NHS FT and Dept of Oncology;  Dr Gianluca Mucciolo CRUK Cambridge Institute (Biffi Lab))

2025-07-10 13:00: Seminar cancelled - Spatial mapping of breast cancer tumour microenvironment in Black British and White British women (Professor Kairbaan Hodivala-Dilke, Centre for Tumour Microenvironment, 2 Barts Cancer Institute, a Cancer Research UK of Excellence, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK)

2025-07-17 09:30: A scientists guide to the art of radiation therapy   and   Neurosurgery for the oncologist  (Dr Raj Jena and Mr Adel Helmy;  Cambridge University Hospitals; Departments of Oncology/ Clinical Nuroscience)

2025-07-22 11:00: LMB Seminar - Modulation of TREM2 function and its role in anti-Amyloid immunotherapeutic approaches (Christian Haass - Ludwig Maximilian University of Munich)

2025-07-24 09:30: Patenting, translating & commercialising research (Prof Rebecca Fitzgerald,  Early Cancer Institute and Dept of Oncology)

2025-09-01 11:00: LMB Seminar - Mechanisms of Translational Control: From Viral Hijacking to Codon-Dependent mRNA Surveillance - In person only (Takuhiro Ito, RIKEN Center for Integrative Medical Sciences)

2025-09-15 11:00: LMB Seminar - The structures and mechanisms that maintain ciliary proteostasis - In person only (Alan Brown, Harvard Medical School)

2025-09-17 11:00: LMB Seminar - Ribosome Upside Down: Co-translational Protein Biogenesis at the Tunnel Exit - In person only (Nenad Ban - ETH Zürich)

2025-09-18 13:00: Next generation medicine: towards eliminating the invisible in ovarian cancer (Professor Ahmed Ahmed, University of Oxford)

2025-09-29 11:00: LMB Seminar - De-novo discovery of macrocyclic peptides and pseudo-natural products for therapeutic innovation (Hiroaki Suga - The University of Tokyo)

2025-10-13 11:00: LMB Seminar - Quorum Sensing Across Domains: From Viruses to Bacteria to Eukaryotes (Bonnie Bassler, Princeton University)

2025-10-16 13:00: Unique Biology and Clinical Impact in Invasive Lobular Carcinoma (Steffi Oesterreich, University of Pittsburgh)

2025-10-23 09:30: Tumour  pathology, structure and nomenclature (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2025-10-24 14:00: Spatial mapping of breast cancer tumour microenvironment in Black British and White British women (Professor Kairbaan Hodivala-Dilke, Centre for Tumour Microenvironment, Barts Cancer Institute, Queen Mary University of London)

2025-10-30 09:30: Core ideas in cancer research 1: genes and genetic instability (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2025-11-03 11:00: LMB Seminar - How the physical sciences can empower biology: Applications of single molecule fluorescence to the biosciences (David Klenerman, University of Cambridge)

2025-11-06 09:30: Core ideas in cancer research 2: cell biology (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2025-11-13 09:30: The mutations that drive cancer  (Dr Paul Edwards, Emeritus Reader in Cancer Biology)

2025-11-20 09:30: Hypoxia, HIFs and cancer (Prof Margaret Ashcroft, Department of Medicine )

2025-11-20 13:00: Targeting the interplay between oncogenic RAS signaling and tumour immune evasion  in lung cancer (Professor Julian Downward, Francis Crick Institute)

2025-11-27 09:30: Cancer stem cells, evolution and heterogeneity  (Professor Brian Huntly, Department of Haematology & Cambridge Stem Cell Institute)

2025-12-04 09:30: DNA repair: translating mechanistic insights towards new cancer therapies.  (Professor Sir Steve Jackson, Cancer Research UK Cambridge Institute)

2025-12-11 09:30: Cancer Immunology and Immunotherapy (Prof Rahul Roychoudhuri, Dept of Pathology)

2025-12-12 13:00: Seminars in Cancer (Andrea Sottoriva, Human Technopole)

2026-01-08 09:30: Cancer metabolism through the lens of Otto Warburg  (Prof Christian Frezza  CECAD Research Center, University Hospital Cologne)

2026-01-15 09:30: Hh signalling and the anti-tumour immune response: biology and new treatment opportunities (Dr Maike de La Roche, Cancer Research UK Cambridge Institute )

2026-01-19 11:00: Max Perutz Lecture - Transport through nuclear pores (Dirk Görlich, Max Planck Institute for Multidisciplinary Sciences)

2026-01-22 09:30: Systems immunology and variation in the human immune system (Professor Adrian Liston, Dept of Pathology)

2026-01-26 11:00: LMB Seminar - New Perspectives on CDKs and Cell Cycle Control (Sir Paul Nurse, The Crick Institute)

2026-01-29 09:30: The role of transcription factors in cancer (Prof Jason Carroll, CRUK Cambridge Institute)

2026-01-29 13:00: Seminars in Cancer (Santiago Zelenay, CRUK Manchester Institute )

2026-02-12 09:30: Cancer virology (Prof John Doorbar, Department of Pathology)

2026-02-19 09:30: Frontiers in paediatric cancer research  (Prof Suzanne Turner)

2026-02-26 09:30: Machine learning: applications to cancer (Dr Mireia Crispin Ortuzar, Early Cancer Institute and Department of Oncology)

2026-02-26 13:00: A complex TiME: How aging drives  tumor progression (Ashani T. Weeraratna, PhD, John Hopkins)

2026-03-05 09:30: The two-hit hypothesis and other mathematical models of cancer (Prof Jamie Blundell;  Early Cancer Institute and Department of Oncology)

2026-03-09 11:00: Francis Crick Lecture - From Cell Atlases to Medicines, with AI (Aviv Regev, Head of Genentech R&ED)

2026-03-12 09:30: Targeted Protein Degradation tools for novel therapeutic strategies in cancer (Dr Catherine Lindon, Dept of Pharmacology)

2026-03-19 09:30: Role of cellular senescence in cancer and ageing: therapeutic opportunities. (Dr Daniel Munoz Espin, Early Cancer Institute and Dept of Oncology)

2026-03-26 09:30: Biological and clinical insights from genome-wide association studies of cancer (Dr Siddhartha Kar, Early Cancer Institute and Dept of Oncology)

2026-03-27 11:00: LMB Seminar - Reconstructing biomolecular condensates for translation (Ruth Lehmann, Whitehead Institute, MIT)

2026-04-01 09:30: Title to be confirmed (Prof Greg Hannon, Cancer Research UK Cambridge Institute)

2026-04-01 09:30: Title to be confirmed (Prof Greg Hannon, Cancer Research UK Cambridge Institute)

2026-04-16 09:30: Mutational signatures: From bytes to bedside (Prof Serena Nik-Zainal, NIHR Research Professor in Genomic Medicine and Bioinfromatics)

2026-04-16 13:00: Seminars in Cancer (Antoine Molaro, iGReD)

2026-04-23 09:30: Decoding genomic chaos - a pancancer compendium of chromosomal instability (Professor Florian Markowetz, Cancer Research UK Cambridge Institute)

2026-04-27 11:00: LMB Seminar - Mechanisms of mRNA packaging and export (Clemens Plaschka, Research Institute of Molecular Pathology, Vienna)

2026-04-30 09:30: From lab to clinic: an introduction to translational research  (Dr James Jones; Cambridge University Hospitals and  Department of Oncology )

2026-05-11 11:00: César Milstein Lecture - Title TBC (Edith Heard, Director General of EMBL and Collège de France)

2026-05-14 09:30: Overview of treatment for non-small cell lung cancer (Dr Huiqi Yang and Dr Nicola Thompson, Cambridge University Hopitals Trust)

2026-05-14 13:00: Seminars in Cancer (Francisco X. Real, CNIO, Madrid)

2026-05-18 11:00: John Kendrew Lecture - Title TBC (Elena Conti, Max Planck Institute of Biochemistry)

2026-05-21 09:30: The role of radiation in cancer care: a spotlight on cancers of the oesophagus, head and neck   (Dr Gill Barnett; Dept of Oncology; Dr Christopher Jones, Dept of Oncology and Cambridge University Hospitals )

2026-06-04 09:30: Using Light for Cancer Detection (Dr  Danielle Harper; Dept of Oncology and Early Cancer Institute )

2026-06-11 09:30: Early cancer clinical trials (Dr Simon Pacey, Cambridge University Hospitals, Dept of Oncology)

2026-06-18 09:30: Pancreatic cancer - the clinical challenge;  Why the microenvironment matters during pancreatic cancer progression and treatment (Dr Kiran Purusothaman, CUH and Dept of Oncology; Dr Wenlong Li, Biffi Lab, CRUK Cammbridge Institute)

2026-06-18 13:00: Seminars in Cancer (Tyler Jacks, PhD, Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology)

2026-06-25 09:30: Clonal haematopoiesis, early detection and pre-leukemia to leukemia development  (Prof Elisa Laurenti, Cambridge Stem Cell Institute and Dept of Haematology)

2026-06-29 11:00: Max Perutz Lecture - Title TBC (Reinhard Lührmann, Max Planck Institute for Biophysical Chemistry)

2026-07-02 09:30: A scientists guide to the art of radiation therapy   and   Neurosurgery for the oncologist  (Dr Raj Jena and Mr Adel Helmy;  Cambridge University Hospitals; Departments of Oncology/ Clinical Nuroscience)