Abstract

Every organ harbours adult stem cells which have the potential for long-term replication, together with the capacities of self-renewal and multi-lineage differentiation. These stem cells function in tissue homeostasis and contribute to regeneration in response to injury. Many cancers are caused by transforming mutations occurring in tissue-specific progenitor cells. Tumours are also organised in a cellular hierarchy, with the so-called cancer stem cells being at the apex. Dr Behrens’ major aim is to elucidate the molecular mechanisms governing stem cell functions in the context of tumour development. Building on his PhD and postdoctoral expertise in animal models of cancer and neurodegeneration, Dr Behrens set up his laboratory at the Cancer Research UK London Research Institute in 2001, now part of the Francis Crick Institute, and has since focused on the function of stem cells in tissue homeostasis and cancer and, more recently, in diabetes.

The talk is open to the public!

Start: 18:00 1hr talk followed by a Q&A, then cheese & wine & a chat!

Where: Pfizer lecture theatre, Chemistry department

Members: Free | Non-members: £3

https://www.facebook.com/events/272385070064555/