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On Growth and Form: Gastrulation and Stem Cells Driving Axis Formation in Amniotes

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If you have a question about this talk, please contact Anne Herrmann .

Two processes are fundamental to the development of most animal embryos: gastrulation (forming the the basic layers of the body from an undifferentiated mass of cells) and gradual building the main body axis, fuelled by stem cell populations. I will present what we learnt in the chick about the molecular interactions specifying cell identity, the collective cell movements in the embryo, and the interplay between morphogenesis and cell fate decisions. I will also discuss what modelling approaches can be used to test whether the mechanisms already identified are enough to explain whole embryo morphogenesis, their robustness and evolvability.

This talk is part of the DAMTP BioLunch series.

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Cambridge University Engineering Department, Lecture Room 12 Clifford Allbutt Lecture Theatre, Clifford Allbutt Building (former LMB building), Addenbrooke's site Average on weekdays: 9170.16532798 kWh

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