Biomolecular adsorption at a silicon/water interface driven by water-structure effects

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• Daniel J. Cole, Theory of Condensed Matter (TCM) Group, Cavendish Laboratory
• Thursday 22 January 2009, 16:00-17:00
• Mott Seminar Room, Cavendish Laboratory, Department of Physics.

If you have a question about this talk, please contact Stephen Walley.

The issue of protein adsorption onto solid surfaces in a wet environment is of great importance for the design and functionalisation of materials in the context of biomedical implants. We investigate the adsorption of the extracellular matrix protein, collagen, on hydrophobic and hydrophilic silicon surfaces using all-atom molecular dynamics. Adhesion is determined by a mutual fit between the hydrophilic/hydrophobic pattern within the protein and the layered water structure at the solid/liquid interface, providing an additional driving force to the hydrophobic effect.

This talk is part of the Physics and Chemistry of Solids Group series.

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• All Cavendish Laboratory Seminars
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• Centre for Health Leadership and Enterprise
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• ME Seminar
• Mott Seminar Room, Cavendish Laboratory, Department of Physics
• Neurons, Fake News, DNA and your iPhone: The Mathematics of Information
• Physics and Chemistry of Solids Group
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