Microglial and myeloid mechanisms of resilience and repair in cerebrovascular disease
- đ¤ Speaker: Barry McColl, University of Edinburgh
- đ Date & Time: Monday 04 October 2021, 16:00 - 17:00
- đ Venue: https://zoom.us/j/95235532571?pwd=dlFPdFRXTGhVeFBXOEtyTXZrN0lxQT09
Abstract
Cerebrovascular disease is one of the most common causes of neurological mortality and morbidity worldwide. In addition to the physical consequences of acute stroke, cerebrovascular dysfunction and pathology causally contribute to cognitive impairment across the spectrum of dementias. Microglia and related myeloid cells are involved in a range of neurovascular interactions and increasing evidence suggests they mediate resilience and adaptive responses to various forms of cerebrovascular disease, both acute and chronic. In this seminar, I will describe our recent work investigating microglial mechanisms of resilience and repair in the context of cerebrovascular disease and highlight the implications for understanding and treating stroke and dementia.
Series This talk is part of the Microglia webinar series series.
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Barry McColl, University of Edinburgh
Monday 04 October 2021, 16:00-17:00