Abstract

Theme: Adaptive Brain Computations

Abstract: Maladaptive emotional memories contribute to the persistence of numerous mental health disorders, including post-traumatic stress disorder (PTSD), drug addiction and obsessive-compulsive disorder (OCD). Using rodent behavioural models of the psychological processes relevant to these disorders, it is possible to identify potential treatment targets for the development of new therapies, including those based upon disrupting the reconsolidation of maladaptive emotional memories. Using examples from rodent models relevant to multiple mental health disorders, this talk will consider some of the opportunities and challenges that this approach provides.

Biorgraphy:Amy Milton is a University Professor in Behavioural Neuroscience in the Department of Psychology at the University of Cambridge, and Director of the Cambridge MiND (Memories in Neuropsychiatric Disorders) Lab. Her research focuses on the neurochemical and molecular mechanisms underlying memory reconsolidation, and their exploitation to develop new treatments for mental health disorders. She also has a strong interest in the development of translationally relevant models of mental health disorders, and facilitating dialogue between basic and clinical neuroscientists working in mental health. Amy’s research, funded by the Medical Research Council, the Wellcome Trust and the Biotechnology and Biological Sciences Research Council, has applications to mental health disorders including drug addiction, post-traumatic stress disorder, and obsessive-compulsive disorder.

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