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From Signaling to Movement - Mathematical and Computational Problems in Cell Motility

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MMVW02 - Collective Behaviour

Cell locomotion is essential for early development, angiogenesis, tissue regeneration, the immune response, and wound healing in multicellular organisms, and plays a very deleterious role in cancer metastasis in humans. Locomotion involves the detection and transduction of extracellular chemical and mechanical signals, integration of the signals into an intracellular signal, and the spatio-temporal control of the intracellular biochemical and mechanical responses that lead to force generation, morphological changes and direct  movement. We will discuss some of the mathematical and computational challenges that the integration of these processes poses and describe recent progress on some component processes.

This talk is part of the Isaac Newton Institute Seminar Series series.

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LB3, Lecture Block, Sidgwick Site Cambridge University Engineering Department, LR 12 Webinar & LT2, Computer Laboratory, William Gates Building.

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