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Jan Rozman (University of Oxford)
Monday 04 September 2023, 11:30-11:50
Shape-tension coupling produces nematic order in an epithelium vertex model
- đ¤ Speaker: Jan Rozman (University of Oxford)
- đ Date & Time: Monday 04 September 2023, 11:30 - 11:50
- đ Venue: Seminar Room 1, Newton Institute
Abstract
We study the vertex model for epithelial tissue mechanics extended to include coupling between the cell shapes and tensions in cell-cell junctions [1]. This coupling represents an active force which drives the system out of equilibrium and leads to the formation of nematic order interspersed with prominent, long-lived +1 defects. The defects in the nematic ordering are coupled to the shape of the cell tiling, affecting cell areas and coordinations. This intricate interplay between cell shape, size, and coordination provides a possible mechanism by which tissues could spontaneously develop long-range polarity through local mechanical forces without resorting to long-range chemical patterning. [1] J. Rozman, R. Sknepnek, and J. M. Yeomans, arXiv preprint arXiv:2212.11037 (2022).
Series This talk is part of the Isaac Newton Institute Seminar Series series.
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