University of Cambridge > Talks.cam > Department of Pharmacology Seminar Series > Implications and molecular mechanisms of MOK, a new signaling kinase in neurodegenerative neuroinflammation

Implications and molecular mechanisms of MOK, a new signaling kinase in neurodegenerative neuroinflammation

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Dr Cintia Roodveldt

University of Seville

Biography

After graduating in Biotechnology (Universidad Nacional del Litoral, Argentina, 1999), Dr Roodveldt completed a PhD (2005, The Weizmann Institute of Science, Israel; Dan S. Tawfik’s lab) in the field of ā€˜enzyme evolution and emergence of new enzyme functions’. She then undertook a Postdoc at Prof. Chris M. Dobson’s lab (University of Cambridge, 2006-2009), investigating the ā€˜molecular mechanisms of Hsp70 chaperone system and a-synuclein aggregates linked to Parkinson’s disease’.

In 2009 she joined David Pozo’s lab, a neuroimmunology lab, at CABIMER Center (Seville, Spain) and started a new line of research on the effect of protein aggregates in innate immunity. Since 2012, and having attained competitive tenure track positions (e.g. ā€˜Ramón y Cajal’ Researcher), they have led a research team studying the ā€˜mechanisms of microglial neuroinflammation triggered by a-synuclein aggregates and novel immunization strategies in Parkinson’. Her current research lines focus on the ā€˜identification of new signalling pathways and therapeutic targets related to immune dysregulation in neurodegenerative diseases, particularly ALS and Parkinson’.

Zoom link: https://zoom.us/j/97143593246?pwd=ckVsZFo2ZGlPei8vVGhoWXg1L0w5QT09

Meeting ID: 971 4359 3246

Passcode: LkGiwj915c

This talk is part of the Department of Pharmacology Seminar Series series.

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