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LMB Seminar: Molecular mechanisms that regulate the first cell fate decisions in human development - In Person Only

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Human embryos must successfully generate embryo-fated cells that eventually give rise to the fetus, and placental- and yolk-sac-fated cells that support continued embryonic development. Embryo-fated cells are established one week after fertilisation of an egg. We know comparatively little about this critical process in human development because human embryos are challenging to study, and few countries fund or allow such studies. My laboratory has optimised advanced molecular and imaging methods, and helped change UK and international regulation, to allow direct functional studies of human embryogenesis. We seek to use these methods to provide fundamental insights into molecular mechanisms that control early human embryonic development. We are particularly interested in understanding the mechanisms that regulate early cell fate decisions and to apply the knowledge gained to stem cell biology.

This talk is part of the MRC LMB Seminar Series series.

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