BSU Seminar: "Multi-state modelling to estimate infectious disease burden"
- đ¤ Speaker: Peter Kirwan, MRC Biostatistics Unit
- đ Date & Time: Tuesday 05 November 2024, 14:00 - 15:00
- đ Venue: MRC Biostatistics Unit, East Forvie Building, Forvie Site Robinson Way Cambridge CB2 0SR.
Abstract
Despite advances in statistical methods and comprehensive public health surveillance, understanding the many facets of infectious disease burden remains a challenge. Questions persist of how fast a disease is spreading, who in society is most at risk, and which interventions might have the capability to save lives.
In this talk I will present research undertaken as part of my PhD at the MRC Biostatistics Unit, with a focus on the development and application of multi-state models to estimate infectious disease burden from observational data. Multi-state models are a flexible approach to estimating risks and lengths of stay, and capable of accounting for data biases and censoring. I will demonstrate the potential of these models to address certain limitations of classical survival analysis methods, with specific application to the HIV epidemic in England and the real-world effectiveness of SARS -CoV-2 vaccination.
Series This talk is part of the MRC Biostatistics Unit Seminars series.
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Peter Kirwan, MRC Biostatistics Unit
Tuesday 05 November 2024, 14:00-15:00