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Professor Melanie Sanford, University of Mighigan, USA
Monday 25 January 2010, 17:00-18:00
Development of New Methods for Catalytic C–H Functionalization: Critical Interplay between Catalyst Design and Mechanistic Analysis
- 👤 Speaker: Professor Melanie Sanford, University of Mighigan, USA
- 📅 Date & Time: Monday 25 January 2010, 17:00 - 18:00
- 📍 Venue: Wolfson Lecture Theatre, Department of Chemistry
Abstract
This seminar will discuss my group’s development of new transition metal catalyzed reactions for the selective functionalization of carbon–hydrogen bonds. The talk will specifically focus on detailed mechanistic investigations and studies of model high oxidation state Pd complexes as a key driver for the development of new catalysts and new reactions in this area. This will be illustrated in the context of several important transformations, including: Pd-catalyzed ligand directed C–H arylation reactions and the Pd and Pt-catalyzed direct functionalization of arenes/alkanes. In each case, mechanistic studies/model complexes have provided critical insights for the development of novel catalysts with enhanced activity and/or selectivity for the key transformation.
Series This talk is part of the Organic Chemistry series.
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