A forward genetic approach to elucidate the microRNA and chromatin silencing pathways in Chlamydomonas reinhardtii

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• Craig Thompson
• Friday 20 May 2011, 13:30-14:00
• Department of Plant Sciences, Large Lecture Theatre.

If you have a question about this talk, please contact Suzy Stoodley.

Although forward genetic screens have identified a number of RNA silencing components, Chlamydomonas reinhardtii provides an ideal system to establish such screens. Due to its ease of mutagenesis, single tissue-type, ability to survive without small RNAs and haploid nature, a wider range of silencing mutants can be obtained through this system. Here, I present three different mutant screens established in C. reinhardtii to identify novel components of the miRNA and chromatin silencing ways and to elucidate how they work in C. reinhardtii. I also outline a reverse genetics approach to determine the mechanism of chromatin silencing in C. reinhardtii

This talk is part of the Plant Sciences Research Seminars series.

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