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Dr Peter Mulligan, Harvard University
Thursday 20 September 2012, 14:30-15:30
Epigenetic Regulatory Complexes in Development and Cancer
- đ¤ Speaker: Dr Peter Mulligan, Harvard University
- đ Date & Time: Thursday 20 September 2012, 14:30 - 15:30
- đ Venue: Sackler Lecture Theatre, CIMR, Level 7
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Dr Ireena Dutta
Abstract
Epigenetic regulatory factors, including enzymes and chromatin binding proteins, have been implicated in virtually every step of tumor progression and the majority of cancer sub-types. Identification of the complexes in which these regulators function has yielded insights into their mechanisms and the biological/cancer processes they regulate. My research has focused primarily on the purification and characterization of complexes of the epigenetic regulators SIRT1 and CDYL , uncovering epigenetic mechanisms in Notch pathway regulation and suppression of oncogenic transformation respectively.
Series This talk is part of the MRC Cancer Unit Seminars series.
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