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A genomic Odyssey of predicting drug response: is Ulysses home yet?

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  • UserDr Federico Innocenti, UNC Institute for Pharmacogenomics and Individualized Therapy
  • ClockTuesday 06 November 2012, 16:00-17:00
  • HouseCRI Lecture Theatre.

If you have a question about this talk, please contact Mala Jayasundera.

Genomic explorations into the heritable genetic basis of the interindividual differences in drug response have recently started. The most comprehensive approach utilized so far has been the application of genome-wide association studies (GWAS) to patients phenotyped with a variety of clinical endpoints. Using oncology as the case model, this presentation will describe 1) the current status of GWAS in oncology, with a focus on heritable markers, 2) the journey of finding associations that have a plausible biological and mechanistic basis, 3) the clinical implications of improving therapies in oncology by using heritable genetic information.

This talk is part of the Cambridge Oncology Seminar Series series.

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