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Mechanisms of Transcriptional Repression during Development.

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If you have a question about this talk, please contact Caroline Newnham .

The aim of our research is to understand how contextual transcription factors regulate gene expression during cell fate determination and differentiation. Our central questions are: Which proteins are involved? How do these proteins interact with each other and RNA polymerase? We are currently focusing on two examples of transcriptional repression observed in the early embryonic development of Drosophila, i) repression by Groucho/TLE family proteins and ii) repression via transcriptional pausing.

This talk is part of the Genetics Seminar series.

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