University of Cambridge > Talks.cam > MRC LMB Seminar Series > Max Perutz Lecture: Five ways that viruses use to enter the animal cell

Max Perutz Lecture: Five ways that viruses use to enter the animal cell

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact Scientific Meetings Co-ordinator.

When viruses enter host cells most of them follow a stepwise program that involves attachment, activation of signaling pathways, endocytosis, penetration into the cytosol, intracellular transport, and finally uncoating of the viral genome. Since these steps depend on cellular functions, hundreds of cellular proteins inadvertently end up assisting the viruses. Using high-end light microscopy, automated siRNA and drug screening as well as biochemical and biophysical approaches, we have analyzed the cell biology of entry of viruses from different families. We find five distinct routes with penetration occurring in the plasma membrane, early endosomes, maturing and late endosomes, macropinosomes, and the ER. I will review the general concepts, and describe in more detail the entry strategies used by influenza A and vaccinia virus.

This talk is part of the MRC LMB Seminar Series series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.

 

© 2006-2024 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity