Ligand-receptor interactions in proteins and membranes

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• P-L Chau, Bioinformatique Structurale, Institut Pasteur, Paris
• Friday 17 February 2006, 14:15-15:15
• IRC in Superconductivity Seminar Room, Cavendish Laboratory.

If you have a question about this talk, please contact Duncan Simpson.

My research investigate how small ligands interact with protein receptors and cell membranes, using as model systems, respectively, the interaction between general anaesthetic (GA) molecules and the gamma-butyric amino acid (GABA) type A receptor, and that between GA and phospholipids. In this project, I apply theoretical methods such as molecular modelling and molecular dynamics, and experimental methods such as neutron reflectometry and Brewster angle microscopy, to define the factors which control these ligand-receptor interactions.

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