![]() |
COOKIES: By using this website you agree that we can place Google Analytics Cookies on your device for performance monitoring. | ![]() |
University of Cambridge > Talks.cam > Cambridge Oncology Seminar Series > Chasing metabolic alterations in cancer
Chasing metabolic alterations in cancerAdd to your list(s) Download to your calendar using vCal
If you have a question about this talk, please contact Dr Ireena Dutta. Hutchison/MRC Research Centre Seminar From a formal scientific perspective, neoplastic transformation could be considered the reflection of the power of evolution for a fundamental scientist. The acquisition of mutations, clonal selection and evolution make tumors dynamic entities in a continuum of heterogeneity. In addition to intrinsic determinants (mutations), cancer cells also acquire behavioral changes in response to the hostile environment where they inhabit or land, which profoundly affects their fate. The highways connecting DNA alterations, extracellular changes and cell fate decisions stem from two plastic communication networks: cellular signaling and metabolic pathways. The idiosyncrasies of cancer metabolism were first noted by Otto Warburg in the nineteen twenties but the concept would not be rescued until the past decade. Together, cancer cell signaling and metabolism are the executors of many of the observed cancer mutations, providing cancer cells with the power to proliferate, survive to stress, and disseminate to distal organs. In this seminar, I will overview how alterations in cancer genes impact on metabolism and conversely, how metabolic mediators can be revealed as potential targets for cancer therapy. This talk is part of the Cambridge Oncology Seminar Series series. This talk is included in these lists:
Note that ex-directory lists are not shown. |
Other listsComputer Laboratory Digital Technology Group (DTG) Meetings Ethics of Big Data JSOCOther talksTreatment Centre Simulation Saving our bumblebees How does functional neuroimaging inform cognitive theory? Player 2 has entered the game - ways of working towards open science Adaptation in log-concave density estimation Beyond crazy: Rationality, irrationality, and conspiracy theory |