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"Fundamentals of a Novel Ionization Process and Implications for Materials Characterization using Mass Spectrometry"

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If you have a question about this talk, please contact Dr Nino Nikolovski .

The introduction of electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) for the mass spectrometric analysis of peptides and proteins had a dramatic impact on biochemistry. Sarah developed a new ionization technique that allows a wide variety of compounds, including peptides, proteins, and protein complexes to be transported directly from a solid-state small molecule matrix to gas-phase ions when placed into the vacuum of a mass spectrometer without the use of high voltage, a laser, or added heat. This matrix and vacuum assisted soft ionization method is suitable for the direct surface analysis of biological materials, including tissue, via mass spectrometry.

This talk is part of the Seminars at the Department of Biochemistry series.

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