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Dr David Fell, Oxford Brookes University
Monday 30 October 2006, 13:30-14:30
Structural Analysis of Genomic Scale Metabolic Networks
- đ¤ Speaker: Dr David Fell, Oxford Brookes University
- đ Date & Time: Monday 30 October 2006, 13:30 - 14:30
- đ Venue: Shared facilities C209/210
Abstract
I will outline the principles of metabolic modelling and the distinction between kinetic and structural models. Since kinetic modelling is not yet practicable for large metabolic networks, the rest of the talk will focus on structural modelling techniques such as elementary modes analysis and enzyme subset analysis. I will illustrate the applications of these techniques, such as pathway discovery, before considering some of the issues involved in scaling up to large networks based on genome annotations and database information. Finally I will present evidence that structural analysis can complement the annotation and transcriptional study of genes for metabolic enzymes.
Series This talk is part of the European Bioinformatics Institute series.
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