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Konstaninou, M (Ruhr-Universitt Bochum)
Wednesday 08 July 2015, 09:40-10:20
Locally optimal designs for errors-in-variables models
⚠️ Important: Design and Analysis of Experiments
- 👤 Speaker: Konstaninou, M (Ruhr-Universitt Bochum)
- 📅 Date & Time: Wednesday 08 July 2015, 09:40 - 10:20
- 📍 Venue: Seminar Room 1, Newton Institute
Abstract
We consider the construction of locally optimal designs for nonlinear regression models when there are measurement errors in the predictors. Corresponding approximate design theory is developed for models subject to a functional error structure for both maximum likelihood and least squares estimation where the latter leads to non-concave optimisation problems. Locally D-optimal designs are found explicitly for the Michaelis-Menten, EMAX and exponential regression models and are then compared with the corresponding designs derived under the assumption of no measurement error in concrete applications.
Series This talk is part of the Isaac Newton Institute Seminar Series series.
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